Results 91 to 100 of about 21,470 (214)
BMC Cell Biology, 2011 Background DYT1 dystonia is an autosomal dominant neurological condition caused by a mutation that removes a single glutamic acid residue (ΔE) from the torsinA (torA) AAA+ protein.
Jeong Danielle Y +3 more
doaj +1 more source
Artist Space Development: Making the Case [PDF]
, 2008 Based on case studies, discusses the challenges advocates of artist space development face, the arguments they make to garner support, the strategic approaches they take, and what they achieve in making artist space a priority in community ...
Florence Kabwasa-Green +1 more
core
Advanced Science, EarlyView.Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma +15 more
wiley +1 more source
Completely positive maps on modules, instruments, extremality problems, and applications to physics
, 2012 Convex sets of completely positive maps and positive semidefinite kernels are considered in the most general context of modules over $C^*$-algebras and a complete charaterization of their extreme points is obtained.
Busch P +7 more
core +1 more source
Advanced Science, EarlyView.Diabetes is an independent risk factor for gallstones. It upregulates CXCR2 expression in hepatic neutrophils, stimulating the formation of NETs that disrupt hepatocellular tight junctions and the liver‐bile barrier. NETs enter bile to accelerate gallstone development, while sarcosine inhibits CXCR2 and NETs production, effectively reducing diabetes ...
Chao Shi +10 more
wiley +1 more source
Advanced Science, EarlyView.Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao +3 more
wiley +1 more source
Recapitulation of molecular regulators of nuclear motion during cell migration
Cell Adhesion & Migration, 2019 Cell migration is a highly orchestrated cellular event that involves physical interactions of diverse subcellular components. The nucleus as the largest and stiffest organelle in the cell not only maintains genetic functionality, but also actively ...
Alexandra Sneider +3 more
doaj +1 more source
Recent advances in understanding the biological roles of the plant nuclear envelope
Nucleus, 2020 The functional organization of the plant nuclear envelope is gaining increasing attention through new connections made between nuclear envelope-associated proteins and important plant biological processes.
Norman Reid Groves +5 more
doaj +1 more source
, 2018 LINC-NIRVANA (LN) is a high resolution, near infrared imager that uses a multiple field-of-view, layer-oriented, multi-conjugate AO system, consisting of four multi-pyramid wavefront sensors (two for each arm of the Large Binocular Telescope, each ...
Arcidiacono, C. +16 more
core +1 more source
Advanced Science, EarlyView.Cyclic nucleotide‐gated (CNG) and hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels share substantial sequence and structural similarity but differ markedly in ion conductance and K+ selectivity. Microsecond‐scale atomistic MD simulations qualitatively reproduced the conductance differences observed in single‐channel recordings and ...
Haoran Liu +3 more
wiley +1 more source