Results 181 to 190 of about 2,488,943 (332)

High-linear energy transfer radiation disrupts natural killer cell surveillance of senescent intestinal cells in the mouse intestine. [PDF]

Mol Biomed
Kumar S, Suman S, Li HH, Angdisen J, Datta K, Fornace AJ.   +5 more
europepmc   +1 more source

Dual-storage phosphor proton therapy dosimetry: Simultaneous quantification of dose and linear energy transfer. [PDF]

Med Phys, 2021
Setianegara J, Mazur TR, Yang D, Li HH.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Reduced beam time and distal linear energy transfer with mini-ridge filters in pencil beam scanning proton therapy. [PDF]

Phys Imaging Radiat Oncol
O'Grady F, Stephenson L, Janson M, Rao AD, Chawla AK, Fan J, Wang P.   +6 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Evaluation of radiophotoluminescent glass dosimeter response for therapeutic spot scanning proton beam: suggestion of linear energy transfer-based correction. [PDF]

J Appl Clin Med Phys, 2021
Nagata J, Yasui K, Omachi C, Toshiyuki T, Shimizu H, Aoyama T, Hayashi N.   +6 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Unravelling the impact of linear energy transfer on micronuclei induction from proton and photon irradiation. [PDF]

Sci Rep
Heaven CJ, Warmenhoven JW, Chadwick AL, Santina E, Honeychurch J, Schmidt CK, Kirkby KJ, Merchant MJ, Henthorn NT.   +8 more
europepmc   +1 more source

Linear energy transfer weighted beam orientation optimization for intensity-modulated proton therapy. [PDF]

Med Phys, 2021
Gu W, Ruan D, Zou W, Dong L, Sheng K.
europepmc   +1 more source

Robust intensity‐modulated proton therapy to reduce high linear energy transfer in organs at risk

Medical Physics (Lancaster), 2017
Y. An, J. Shan, Samir H. Patel, W. Wong, S. Schild, Xiaoning Ding, M. Bues, Wei Liu   +7 more
semanticscholar   +1 more source