Results 261 to 270 of about 2,488,943 (332)

Robust Optimization for Intensity-Modulated Proton Therapy to Redistribute High Linear Energy Transfer (LET) from Nearby Critical Organs to Tumors in Head and Neck Cancer.

International Journal of Radiation Oncology, Biology, Physics, 2020
PURPOSE We propose linear-energy-transfer (LET)-guided robust optimization in intensity-modulated proton therapy (IMPT) for head-and-neck (H&N) cancer. This method simultaneously considers LET and physical dose distributions of tumors and organs-at-risk (
Chenbin Liu, Samir H. Patel, J. Shan, S. Schild, C. Vargas, W. Wong, Xiaoning Ding, M. Bues, Wei Liu   +8 more
semanticscholar   +1 more source

Linear energy transfer of proton clusters

Physics in Medicine and Biology, 2011
In conventional particle accelerators, protons are produced in long pulses, in which the average inter-proton distance is in the order of tens of centimeters or more. Therefore, the radiobiology of conventionally accelerated protons is primarily governed by the interaction of a single proton with the cell.
E, Fourkal, I, Velchev, C-M, Ma, J, Fan
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Spatial correlation of linear energy transfer and relative biological effectiveness with suspected treatment related toxicities following proton therapy for intracranial tumors.

Medical Physics (Lancaster), 2019
PURPOSE The enhanced relative biological effectiveness (RBE) at the end of the proton range might increase the risk of radiation-induced toxicities.
Jakob Ödén, I. Toma-Dasu, P. Witt Nyström, E. Traneus, A. Dasu   +4 more
semanticscholar   +1 more source

Introducing Proton Track-End Objectives in Intensity Modulated Proton Therapy Optimization to Reduce Linear Energy Transfer and Relative Biological Effectiveness in Critical Structures.

International Journal of Radiation Oncology, Biology, Physics, 2019
PURPOSE We propose the use of proton track-end objectives in intensity modulated proton therapy (IMPT) optimization to reduce the linear energy transfer (LET) and the relative biological effectiveness (RBE) in critical structures.
E. Traneus, Jakob Ödén
semanticscholar   +1 more source

On the revised concept of linear energy transfer

Radiation and Environmental Biophysics, 1995
The quantities linear energy transfer or restricted linear energy transfer are utilized in calculations that link absorbed dose to the fluence distribution of a radiation field. The computations provide approximations to absorbed dose in terms of the intermediate quantity cema or reduced cema.
J, Chen, A M, Kellerer, H H, Rossi
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Irradiation of Atactic Polystyrene: Linear Energy Transfer Effects

The Journal of Physical Chemistry B, 2008
Atactic glassy polystyrene (PS) has been irradiated in anoxic conditions by electron and ion beams. The induced modifications were followed, in situ, by Fourier transform infrared spectroscopy (FTIR). In-film modifications and hydrocarbon gas release were followed.
Ferry, Muriel, Ngono-Ravache, Yvette, Picq, Virginie, Balanzat, Emmanuel   +3 more
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Fluorescent resonant excitation energy transfer in linear polyenes

The Journal of Chemical Physics, 2010
We have studied the dynamics of excitation transfer between two conjugated polyene molecules whose intermolecular separation is comparable to the molecular dimensions. We have employed a correlated electron model that includes both the charge-charge, charge-bond, and bond-bond intermolecular electron repulsion integrals.
Das, Mousumi, Ramasesha, Suryanarayanasastry   +1 more
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Analytical linear energy transfer calculations for proton therapy

Medical Physics, 2003
As the relative biological effectiveness of protons depends on the linear energy transfer (LET), simple methods for LET calculations are desired for the optimization of proton therapy. This work provides an analytical model for the LET on the central axis of broad proton beams in water, which can also be applied to spread-out Bragg peaks. For realistic
Jan J, Wilkens, Uwe, Oelfke
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Hybrid 3D analytical Linear Energy Transfer calculation algorithm based on pre-calculated data from Monte Carlo simulations.

Medical Physics (Lancaster), 2019
PURPOSE The dose-averaged linear-energy-transfer (LETd ) for intensity-modulated proton therapy (IMPT) calculated by 1D analytical models deviates from more accurate but time-consuming Monte-Carlo (MC) simulations.
W. Deng, Xiaoning Ding, J. Younkin, Jiajian Shen, M. Bues, S. Schild, Samir H. Patel, Wei Liu   +7 more
semanticscholar   +1 more source

A Spatially Restricted Linear Energy Transfer Equation

Radiation Research, 1992
An analytical expression is developed for calculating the average energy deposited by an ion in a volume with dimensions less than the range of the secondary electrons produced. The expression is obtained by including two additional terms in an energy-restricted linear-energy-transfer equation. The usual energy-restricted expression accounts for energy
openaire   +2 more sources