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Obesity and its comorbidities, including type 2 diabetes and cardiovascular disease, are straining our healthcare system, necessitating the development of novel strategies for weight loss. Lifestyle modifications, such as exercise and caloric restriction,
Laura J. den Hartigh
semanticscholar +1 more source
Fatty acid esters of hydroxy fatty acids (FAHFAs) are a recently discovered class of biologically active lipids. Here we identify the linoleic acid ester of 13-hydroxy linoleic acid (13-LAHLA) as an anti-inflammatory lipid.
Matthew J. Kolar+8 more
semanticscholar +1 more source
Dietary medium chain fatty acid supplementation leads to reduced VLDL lipolysis and uptake rates in comparison to linoleic acid supplementation. [PDF]
Dietary medium chain fatty acids (MCFA) and linoleic acid follow different metabolic routes, and linoleic acid activates PPAR receptors. Both these mechanisms may modify lipoprotein and fatty acid metabolism after dietary intervention.
Daniël B van Schalkwijk+9 more
doaj +1 more source
Physicochemical properties of soybean β-conglycinin-based films affected by linoleic acid
To explore the interaction between lipids and proteins during emulsion film formation, the linoleic acid concentration effects on the physicochemical properties of soybean β-conglycinin (7S) films were studied.
Rongxue Zhou+5 more
doaj
Omega-6 vegetable oils as a driver of coronary heart disease: the oxidized linoleic acid hypothesis
The intake of omega-6 vegetable oils, particularly soybean oil, began to increase in the USA starting in the early 1900s at a time when the consumption of butter and lard was on the decline.1 This caused a more than two-fold increase in the intake of ...
J. DiNicolantonio, J. O’Keefe
semanticscholar +1 more source
Effects of conjugated linoleic acid on linoleic and linolenic acid metabolism in man [PDF]
Evidence from animal studies suggests that conjugated linoleic acid (CLA) modulates plasma and tissue appearance of newly synthesized PUFA. The effects of a 1·2g (0·5% energy) daily intake of thecis-9,trans-11 (c9,t11) isomer of CLA,trans-10,cis-12 (t10,c12) isomer of CLA or olive oil (placebo) on linoleic acid (LA) and linolenic acid (LNA) metabolism ...
Riitta Freese+4 more
openaire +2 more sources
Various fatty acyl lipid mediators are derived from dietary polyunsaturated fatty acids (PUFAs) and modulate nociception. The modern diet is rich in linoleic acid, which is associated with nociceptive hypersensitivities and may present a risk factor for ...
Nada Birkic+4 more
doaj +1 more source
Omega-3 α-linolenic acid and omega-6 linoleic acid are essential fatty acids for health maintenance of human and animals because they are not synthesized in vivo.
Kang-Sig Kim, Hum-Dai Park
doaj +1 more source
Conjugated Linoleic Acid: Potential Health Benefits as a Functional Food Ingredient.
Conjugated linoleic acid (CLA) has drawn significant attention since the 1980s for its various biological activities. CLA consists mainly of two isomers, cis-9,trans-11 and trans-10,cis-12, and the mixture of these two (CLA mix or 50:50) has been ...
Jun Ho Kim+3 more
semanticscholar +1 more source
Atheroprotective effects of conjugated linoleic acid.
Atherosclerosis, the underlying cause of heart attack and strokes, is a progressive dyslipidaemic and inflammatory disease where monocyte-derived macrophage cells play a pivotal role.
R. Bruen, S. Fitzsimons, O. Belton
semanticscholar +1 more source