Results 21 to 30 of about 76,830 (260)

Purification of oleic acid and linoleic acid

open access: yesJournal of Lipid Research, 1983
To permit kinetic studies of the reactivity of unsaturated fatty acids towards oxygen radicals, it is essential to remove traces of hydroperoxides and other conjugated lipid impurities commonly present in commercial samples.
R L Arudi, M W Sutherland, B H Bielski
doaj   +1 more source

A dual, concentration-dependent absorption mechanism of linoleic acid by rat jejunum in vitro.

open access: yesJournal of Lipid Research, 1979
Linoleic acid absorption was studied using everted rat jejunal sacs. At low concentrations (42-1260 microM), the relationship between linoleic acid concentration and its absorption rate fitted best to a rectangular hyperbola.
S L Chow, D Hollander
doaj   +1 more source

Reaction of linoleic acid hydroperoxide with thiobarbituric acid.

open access: yesJournal of Lipid Research, 1978
The linoleic acid hydroperoxide obtained by enzymatic peroxidation of linoleic acid was found to react with thiobarbituric acid to yield a red pigment. The optimum pH for the reaction was found to be 4.0.
H Ohkawa, N Ohishi, K Yagi
doaj   +1 more source

Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells

open access: yesLipids in Health and Disease, 2012
Objectives Hepatic inflammation and degeneration induced by lipid depositions may be the major cause of nonalcoholic fatty liver disease. In this study, we tried to investigate the effects of saturated and unsaturated fatty acids on hepatoma cell ...
Zhang Yong   +4 more
doaj   +1 more source

Exploration of the Mechanism of Linoleic Acid Metabolism Dysregulation in Metabolic Syndrome

open access: yesGenetics Research, 2022
We aimed to explore the mechanism of the linoleic acid metabolism in metabolic syndrome (MetS). RNA-seq data for 16 samples with or without MetS from the GSE145412 dataset were collected.
Yan Wen, Yawen Shang, Qing Wang
doaj   +1 more source

Direct effects of linoleic and linolenic acids on bovine uterine function using in vivo and in vitro studies

open access: yesThe Journal of Reproduction and Development, 2021
The aim of the present study was to evaluate the effects of continuous administration of linoleic acid or linolenic acid into the intra-uterine horn, ipsilateral to the corpus luteum, on the duration of the estrous cycle and plasma progesterone (P4 ...
Ryosuke SAKUMOTO   +2 more
doaj   +1 more source

Linoleic acid exhibits anti-proliferative and anti-invasive activities in endometrial cancer cells and a transgenic model of endometrial cancer

open access: yesCancer Biology & Therapy
Emerging evidence has provided considerable insights into the integral function of reprogramming fatty acid metabolism in the carcinogenesis and progression of endometrial cancer. Linoleic acid, an essential fatty acid with the highest consumption in the
Jianqing Qiu   +11 more
doaj   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

Effect of Linoleic Acid on Cholesterol Levels in a High-Fat Diet-Induced Hypercholesterolemia Rat Model

open access: yesMetabolites, 2022
Cardiovascular disease is the leading cause of morbidity and mortality worldwide, accounting for almost one-third of all deaths. The risk factors for developing this disease include high levels of serum total cholesterol (TC), triglycerides (TG), and low-
Nurul Adila Azemi   +5 more
doaj   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez   +6 more
wiley   +1 more source

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