Results 41 to 50 of about 107,686 (309)

Conjugated linoleic acid supplementation reduces peripheral blood mononuclear cell interleukin-2 production in healthy middle-aged males.

, 2007
Conjugated linoleic acid (CLA) refers to geometric and positional isomers of linoleic acid. Animal studies have shown that CLA modulates the immune system and suggest that it may have a therapeutic role in inflammatory disorders.
Nugent, Anne P, Cashman, Kevin D, Doyle, Lorna, Mullen, Anne, Cashman, Kevin D., Moloney, Fiona, Roche, Helen M., Nugent, Anne P., Roche, Helen M   +8 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Linoleic acid exhibits anti-proliferative and anti-invasive activities in endometrial cancer cells and a transgenic model of endometrial cancer

Cancer Biology & Therapy
Emerging evidence has provided considerable insights into the integral function of reprogramming fatty acid metabolism in the carcinogenesis and progression of endometrial cancer. Linoleic acid, an essential fatty acid with the highest consumption in the
Jianqing Qiu, Ziyi Zhao, Hongyan Suo, Sarah E. Paraghamian, Gabrielle M. Hawkins, Wenchuan Sun, Xin Zhang, Tianran Hao, Beor Deng, Xiaochang Shen, Chunxiao Zhou, Victoria Bae-Jump   +11 more
doaj   +1 more source

Hydrogenation alternatives: effects of trans fatty acids and stearic acid versus linoleic acid on serum lipids and lipoproteins in humans.

Journal of Lipid Research, 1992
The objective of this study was to compare the effects of linoleic acid (cis,cis-C18:2(n-6)) and its hydrogenation products elaidic (trans-C18:1(n-9)) and stearic acid (C18:0) on serum lipoprotein levels in humans.
PL Zock, MB Katan
doaj   +1 more source

Inactivation of Enzymes by Linoleic Acid Hydroperoxides and Linoleic Acid

Agricultural and Biological Chemistry, 1970
The inactivation of the enzymes by linoleic acid hydroperoxides (LAHPO) was tested in connection with the toxicity of oxidized fat. At the same time, the inhibition of enzyme activities by linoleic acid was also tested. Ribonuclease (RNase), trypsin, chymotrypsin and pepsin which are considered to be simple proteins and not to be SH-enzymes were chosen
MATSUSHITA, Setsuro, KOBAYASHI, Masayo, NITTA, YUKI   +2 more
openaire   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Metabolism of U13C-labeled linoleic acid in lactating women

Journal of Lipid Research, 1998
Long chain polyunsaturated fatty acids are nutritionally important constituents of breast milk. The origin of these fatty acids in milk has not been clearly identified.
H. Demmelmair, M. Baumheuer, B. Koletzko, K. Dokoupil, G. Kratl   +4 more
doaj   +1 more source

Exploration of the Mechanism of Linoleic Acid Metabolism Dysregulation in Metabolic Syndrome

Genetics Research, 2022
We aimed to explore the mechanism of the linoleic acid metabolism in metabolic syndrome (MetS). RNA-seq data for 16 samples with or without MetS from the GSE145412 dataset were collected.
Yan Wen, Yawen Shang, Qing Wang
doaj   +1 more source

Effect of Linoleic Acid on Cholesterol Levels in a High-Fat Diet-Induced Hypercholesterolemia Rat Model

Metabolites, 2022
Cardiovascular disease is the leading cause of morbidity and mortality worldwide, accounting for almost one-third of all deaths. The risk factors for developing this disease include high levels of serum total cholesterol (TC), triglycerides (TG), and low-
Nurul Adila Azemi, Ahmad Khusairi Azemi, Luqman Abu-Bakar, Vigneswari Sevakumaran, Tengku Sifzizul Tengku Muhammad, Noraznawati Ismail   +5 more
doaj   +1 more source

Myosin-cross-reactive antigen (MCRA) protein from Bifidobacterium breve is a FAD-dependent fatty acid hydratase which has a function in stress protection [PDF]

, 2011
peer-reviewedBackground The aim of this study was to determine the catalytic activity and physiological role of myosin-cross-reactive antigen (MCRA) from Bifidobacterium breve NCIMB 702258. MCRA from B.
Cornelia Göbel, Liavonchanka, Alena, Fitzgerald, Gerald F, Gerald F Fitzgerald, STANTON, CATHERINE, Gobel, Cornelia, Eva Rosberg-Cody, Alena Liavonchanka, Feussner, Ivo, Goebel, Cornelia, O'Sullivan, Orla, O\u27Sullivan, Orla, Ivo Feussner, Ross, R. Paul, R Paul Ross, Rosberg-Cody, Eva, Fitzgerald, Gerald F., Catherine Stanton, Ross, R Paul, Orla O'Sullivan, R Ross   +20 more
core   +1 more source