Results 41 to 50 of about 169,891 (305)

Linoleic acid exhibits anti-proliferative and anti-invasive activities in endometrial cancer cells and a transgenic model of endometrial cancer

Cancer Biology & Therapy
Emerging evidence has provided considerable insights into the integral function of reprogramming fatty acid metabolism in the carcinogenesis and progression of endometrial cancer. Linoleic acid, an essential fatty acid with the highest consumption in the
Jianqing Qiu, Ziyi Zhao, Hongyan Suo, Sarah E. Paraghamian, Gabrielle M. Hawkins, Wenchuan Sun, Xin Zhang, Tianran Hao, Beor Deng, Xiaochang Shen, Chunxiao Zhou, Victoria Bae-Jump   +11 more
doaj   +1 more source

Hydrogenation alternatives: effects of trans fatty acids and stearic acid versus linoleic acid on serum lipids and lipoproteins in humans.

Journal of Lipid Research, 1992
The objective of this study was to compare the effects of linoleic acid (cis,cis-C18:2(n-6)) and its hydrogenation products elaidic (trans-C18:1(n-9)) and stearic acid (C18:0) on serum lipoprotein levels in humans.
PL Zock, MB Katan
doaj   +1 more source

Effect of Linoleic Acid on Cholesterol Levels in a High-Fat Diet-Induced Hypercholesterolemia Rat Model

Metabolites, 2022
Cardiovascular disease is the leading cause of morbidity and mortality worldwide, accounting for almost one-third of all deaths. The risk factors for developing this disease include high levels of serum total cholesterol (TC), triglycerides (TG), and low-
Nurul Adila Azemi, Ahmad Khusairi Azemi, Luqman Abu-Bakar, Vigneswari Sevakumaran, Tengku Sifzizul Tengku Muhammad, Noraznawati Ismail   +5 more
doaj   +1 more source

Starch and oil in the donor cow diet and starch in substrate differently affect the in vitro ruminal biohydrogenation of linoleic and linolenic acids [PDF]

, 2011
Trans isomers of fatty acids exhibit different health properties. Among them, trans-10,cis-12 conjugated linoleic acid has negative effects on milk fat production and can affect human health.
A. Troegeler-Meynadier, A. Zened, Akraim, Baumgard, Choi, Destaillats, Enjalbert, F. Enjalbert, Fuentes, Gervais, Glasser, Griinari, Griinari, Griinari, Harfoot, Ip, Jouany, Kalscheur, Kemp, Kemp, L. Cauquil, Legendre, Loisel, Loor, Loor, Lourenço, M.C. Nicot, Michelland, Moate, Park, Piperova, Pottier, Privé, Roy, S. Combes, Shingfield, Tricon, Troegeler-Meynadier, Troegeler-Meynadier, Van Nevel, Wallace, Weimer, Winkler, Y. Farizon, Yang   +44 more
core   +2 more sources

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Metabolism of U13C-labeled linoleic acid in lactating women

Journal of Lipid Research, 1998
Long chain polyunsaturated fatty acids are nutritionally important constituents of breast milk. The origin of these fatty acids in milk has not been clearly identified.
H. Demmelmair, M. Baumheuer, B. Koletzko, K. Dokoupil, G. Kratl   +4 more
doaj   +1 more source

An agronomic evaluation of new safflower (Carthamus tinctorius L.) germplasm for seed and oil yields under Mediterraean climate conditions [PDF]

, 2019
Interest in oilseed crops for agro-industrial research and development projects has increased in the Mediterranean area, in recent years. Saffloower (Carthamus tinctorius L.) is of potential interest for agriculture mainly due to fatty acid content ...
La Bella S, Lazzeri L, Leto C, Licata M, Matteo R, Tuttolomondo T   +5 more
core   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Comparison of PUFA profiles in the blood and in follicular fluid and its association with follicular dynamics after PGF2α induced luteolysis in dairy cows [PDF]

, 2016
The objectives of the present study were to examine the fatty acid (FA) profiles in serum and in the follicular fluid (FF) and the association between polyunsaturated fatty acid level (PUFA) and follicular growth dynamics following induced luteolysis in ...
Adamov, Nikola, Atanasov, Branko, Davkov, Filip, Dovenski, Toni, Hajrulai-Musliu, Zehra, Hostens, Miel, Opsomer, Geert, Uzunov, Risto, Velev, Romel   +8 more
core   +3 more sources

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source