Results 41 to 50 of about 76,830 (260)

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

Conjugated linoleic acid as a novel insecticide targeting the agricultural pest Leptinotarsa decemlineata.

PLoS ONE, 2019
The Colorado Potato Beetle, Leptinotarsa decemlineata, is a major agricultural pest of solanaceous crops in the United States. Historically, a multitude of insecticides have been used to control problematic populations.
Justin Clements, Russell L Groves, JoAnn Cava, Caroline C Barry, Scott Chapman, Jake M Olson   +5 more
doaj   +1 more source

Concentration of trans-vaccenic and rumenic acids in the milk from grazing cows supplemented with palm oil, rice bran or whole cottonseed

Revista Brasileira de Zootecnia, 2014
The changes in the concentration of trans-vaccenic (C18:1t-11) and rumenic (C18:2c-9,t-11) acids in the milk from cows grazing on Pennisetum clandestinum, fed a supplement containing palm oil, rice bran or whole cottonseed were evaluated.
Gastón Adolfo Castaño, Martha Lucía Pabón, Juan Evangelista Carulla   +2 more
doaj   +1 more source

The Oleic/Linoleic Acid Ratio in Olive (Olea europaea L.) Fruit Mesocarp Is Mainly Controlled by OeFAD2-2 and OeFAD2-5 Genes Together With the Different Specificity of Extraplastidial Acyltransferase Enzymes

Frontiers in Plant Science, 2021
Fatty acid composition of olive oil has an important effect on the oil quality to such an extent that oils with a high oleic and low linoleic acid contents are preferable from a nutritional and technological point of view.
M. Luisa Hernández, M. Dolores Sicardo, Angjelina Belaj, José M. Martínez-Rivas   +3 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Inclusion of fresh forage in the ration for dairy cows: effects on CLA and trans C18:1 isomers content of milk fat

Italian Journal of Animal Science, 2010
Milk fat is the richest natural source of conjugated linoleic acid (CLA) isomers. The 9-cis, 11-trans CLA isomer (rumenic acid, RA) origins from two pathways: as an intermediate of the rumen biohydrogenation process of linoleic acid or as the product of ...
P. Secchiari, M. Antongiovanni, M. Mele, M. Del Viva, A. Serra   +4 more
doaj   +1 more source

Metarhizium anisopliae Mitigates the Phytotoxicity of Lead and Nanoplastics on Rice by Modifying Physiological, Transcriptomic, Metabolomic Activities, and Soil Microbiome

Advanced Science, EarlyView.
Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng, Qi Yan, Muhammad Umair Hassan, Muhammad Imran, Fasih Ullah Haider, Jianfeng Liang, Xingmin Wang, Shaukat Ali   +7 more
wiley   +1 more source

Radiohomogeneity of H3- and C14-labeled linoleic acid in vivo

Journal of Lipid Research, 1965
A mixture of linoleic acid-1-C14 and linoleic acid labeled with H3 in the chain was administered to rats, and the H3/C14 ratio in the linoleic acid recovered from liver and adipose tissue of the rat was compared with that in the administered mixture ...
Demetrios Sgoutas, Moon Ja Kim, Fred A. Kummerow   +2 more
doaj   +1 more source

Genome-Wide Association Analysis-Based Mining of Quality Genes Related to Linoleic and Linolenic Acids in Soybean

Agriculture, 2023
Soybean fat contains five principal fatty acids, and its fatty acid composition and nutritional value depend on the type of soybean oil, storage duration, and conditions.
Jiabao Wang, Lu Liu, Qi Zhang, Tingting Sun, Piwu Wang   +4 more
doaj   +1 more source

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

Advanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang, Yuting Liu, Shufan Jiang, Zilin Fang, Mengda Jiang, Xiaofeng Tao, Tianyi Zhu, Jipeng Li, Sijie Fang, Xuefei Song, Yinwei Li, Jing Sun, Chuanjun Tong, Zhengrun Gao, Huifang Zhou, Xianqun Fan   +15 more
wiley   +1 more source