Cerebral lipid accumulation in Chanarin–Dorfman Syndrome [PDF]
Chanarin-Dorfman Syndrome (CDS) is caused by a defect in the CGI-58/ABHD5 gene resulting in a deficiency of CGI-58 and in intracellular accumulation of triacylglycerol in skin and liver. Patients are mainly characterized by congenital ichthyosis, but the clinical phenotype is very heterogeneous. Distinct brain involvement has never been described.
Huigen, C.D.G. +12 more
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Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation [PDF]
Microglia become increasingly dysfunctional with aging and contribute to the onset of neurodegenerative disease (NDs) through defective phagocytosis, attenuated cholesterol efflux, and excessive secretion of pro-inflammatory cytokines. Dysfunctional microglia also accumulate lipid droplets (LDs); however, the mechanism underlying increased LD load is ...
Bailey A. Loving +6 more
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Comparative proteomics profile of lipid-cumulating oleaginous yeast: an iTRAQ-coupled 2-D LC-MS/MS analysis. [PDF]
Accumulation of intracellular lipid in oleaginous yeast cells has been studied for providing an alternative supply for energy, biofuel. Numerous studies have been conducted on increasing lipid content in oleaginous yeasts.
Jiahua Shi +3 more
doaj +1 more source
A transcriptional regulatory module controls lipid accumulation in soybean.
Soybean (Glycine max) is one of the most important oilseed crops. However, limited information is known about the regulatory mechanism of oil accumulation in soybean.
Long Lu +17 more
semanticscholar +1 more source
Increased FAT/CD36 cycling and lipid accumulation in myotubes derived from obese type 2 diabetic patients. [PDF]
BACKGROUND: Permanent fatty acid translocase (FAT/)CD36 relocation has previously been shown to be related to abnormal lipid accumulation in the skeletal muscle of type 2 diabetic patients, however mechanisms responsible for the regulation of FAT/CD36 ...
Celine Aguer +6 more
doaj +1 more source
Fungal Lipids: The Biochemistry of Lipid Accumulation [PDF]
derived from agricultural products, and the remainder coming from animal and marine sources. It is essential to find new sources for oil and protein supplement with concern to the nutritional problems accompanying the rapid growth of world's population.
openaire +2 more sources
Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells [PDF]
Wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control.
Ant, Thomas H. +9 more
core +3 more sources
Introduction: The occurrence of fatty liver disease, resulting from the accumulation of excessive fat within the liver, has been showing a significant and rapid increase.
Yun-Mi Kang +6 more
doaj +1 more source
Total Lipid and Fatty Acid Composition in Male and Female Larvae of Indian-Meal Moth and Almond Moth (Lepidoptera: Pyralidae) [PDF]
The total body lipid and fatty acid composition of last instar larvae of the Indian-meal moth, Plodia interpunctella, and almond moth, Cadra cautella, reared on a turkey mash diet was determined. Male P.
Cutkomp, L. K, Subramanyam, Bh.
core +3 more sources
Ectopic lipid accumulation in skeletal muscle and liver drives the pathogenesis of diabetes mellitus type 2 (DMT2). Mild hyperbilirubinaemia has been repeatedly suggested to play a role in the prevention of DMT2 and is known for its capacity to shape an ...
Claudia A. Hana +18 more
doaj +1 more source

