Results 41 to 50 of about 38,606 (200)
Mechanisms of Membrane Curvature Generation in Membrane Traffic
Membranes, 2012 During the vesicular trafficking process, cellular membranes undergo dynamic morphological changes, in particular at the vesicle generation and fusion steps.
Hye-Won Shin +2 more
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Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry
Scientific Reports, 2021 SARS-CoV-2 spike proteins are responsible for the membrane fusion event, which allows the virus to enter the host cell and cause infection. This process starts with the binding of the spike extramembrane domain to the angiotensin-converting enzyme 2 ...
Alessandra Luchini +11 more
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Frontiers in Molecular Biosciences, 2021 The fusion pore is the initial narrow connection that forms between fusing membranes. During vesicular release of hormones or neurotransmitters, the nanometer-sized fusion pore may open-close repeatedly (flicker) before resealing or dilating irreversibly,
Joerg Nikolaus +12 more
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Biomolecules, 2023 Mitochondria are highly dynamic organelles that constantly undergo fusion and fission events to maintain their shape, distribution and cellular function.
Anaïs Vlieghe +5 more
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A Dynamic Model of Fusion Pores in Lipid Bilayers [PDF]
Biophysical Journal, 2012 Biological membranes remodel and change shape in processes like endocytosis, exocytosis, hemifusion, and the expansion of fusion pores. Since the length scale of these processes is generally quite small, computational models are needed to resolve the time course of the membrane.
Ryham, Rolf +3 more
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Molecular Dynamics Investigation of Lipid-Specific Interactions with a Fusion Peptide
BiomoleculesThe HIV-1 fusion peptide, which is a short hydrophobic peptide from the gp41 coat glycoprotein that participates in the infection of a cell, interacts with model lipid bilayer membranes in a concentration-dependent manner.
William T. Heller
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Alpha-Synuclein Continues to Enhance SNARE-Dependent Vesicle Docking at Exorbitant Concentrations
Frontiers in Neuroscience, 2019 Recently, Parkinson’s disease-associated α-synuclein (αS) has emerged as an important regulator for SNARE-dependent vesicle fusion. However, it is controversial if excessive accumulation of αS, even in the absence of aggregation, impairs ...
Brenden J. D. Hawk +2 more
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Atomic Force Microscope Studies of the Fusion of Floating Lipid Bilayers [PDF]
Biophysical Journal, 2007 This study investigated the fusion of apposing floating bilayers of egg L-alpha-phosphatidylcholine (egg PC) or 1,2-dimyristoyl-sn-glycero-3-phosphocholine. Atomic force microscope measurements of fusion forces under different compression rates were acquired to reveal the energy landscape of the fusion process under varied lipid composition and ...
Abdulreda, Midhat H., Moy, Vincent T.
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Vesicle Fusion Observed by Content Transfer across a Tethered Lipid Bilayer [PDF]
Biophysical Journal, 2011 Synaptic transmission is achieved by exocytosis of small, synaptic vesicles containing neurotransmitters across the plasma membrane. Here, we use a DNA-tethered freestanding bilayer as a target architecture that allows observation of content transfer of individual vesicles across the tethered planar bilayer.
Rawle, Bob +4 more
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Frontiers in Molecular Biosciences, 2022 Hemagglutinin (HA) mediated fusion of influenza virus envelope with host lipid membrane is a critical step warrantying virus entry to the cell. Despite tremendous advances in structural biology methods, the knowledge concerning the details of HA2 subunit
Michal Michalski, Piotr Setny
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