Results 41 to 50 of about 107,533 (320)

Two modes of fusogenic action for influenza virus fusion peptide.

open access: yesPLoS Computational Biology, 2023
The entry of influenza virus into the host cell requires fusion of its lipid envelope with the host membrane. It is catalysed by viral hemagglutinin protein, whose fragments called fusion peptides become inserted into the target bilayer and initiate its ...
Michal Michalski, Piotr Setny
doaj   +1 more source

A Coiled-Coil Peptide Shaping Lipid Bilayers upon Fusion [PDF]

open access: yesBiophysical Journal, 2016
A system based on two designed peptides, namely the cationic peptide K, (KIAALKE)3, and its complementary anionic counterpart called peptide E, (EIAALEK)3, has been used as a minimal model for membrane fusion, inspired by SNARE proteins. Although the fact that docking of separate vesicle populations via the formation of a dimeric E/K coiled-coil ...
Rabe, M.   +10 more
openaire   +5 more sources

Single-molecule study of full-length NaChBac by planar lipid bilayer recording. [PDF]

open access: yesPLoS ONE, 2017
Planar lipid bilayer device, alternatively known as BLM, is a powerful tool to study functional properties of conducting membrane proteins such as ion channels and porins.
Andrew Jo   +4 more
doaj   +1 more source

Leaflet Tensions Control the Spatio-Temporal Remodeling of Lipid Bilayers and Nanovesicles

open access: yesBiomolecules, 2023
Biological and biomimetic membranes are based on lipid bilayers, which consist of two monolayers or leaflets. To avoid bilayer edges, which form when the hydrophobic core of such a bilayer is exposed to the surrounding aqueous solution, a single bilayer ...
Reinhard Lipowsky   +7 more
doaj   +1 more source

Microcavity supported lipid membranes: versatile platforms for building asymmetric lipid bilayers and for protein recognition [PDF]

open access: yes, 2019
Microcavity supported lipid bilayers (MSLB) are contact-free membranes suspended across aqueousfilled pores that maintain the lipid bilayer in a highly fluidic state and free from frictional interactions with substrate.
Berselli, Guilherme   +4 more
core   +1 more source

Voltage Sensing in Bacterial Protein Translocation [PDF]

open access: yes, 2020
The bacterial channel SecYEG efficiently translocates both hydrophobic and hydrophilic proteins across the plasma membrane. Translocating polypeptide chains may dislodge the plug, a half helix that blocks the permeation of small molecules, from its ...
Bondar, Ana-Nicoleta   +5 more
core   +1 more source

Streamlined Fabrication of Hybrid Lipid Bilayer Membranes on Titanium Oxide Surfaces: A Comparison of One- and Two-Tail SAM Molecules

open access: yesNanomaterials, 2022
There is broad interest in fabricating cell-membrane-mimicking, hybrid lipid bilayer (HLB) coatings on titanium oxide surfaces for medical implant and drug delivery applications.
Tun Naw Sut   +5 more
doaj   +1 more source

Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. [PDF]

open access: yes, 2012
The molecular underpinnings of synaptic vesicle fusion for fast neurotransmitter release are still unclear. Here, we used a single vesicle-vesicle system with reconstituted SNARE and synaptotagmin-1 proteoliposomes to decipher the temporal sequence of ...
Brunger, Axel T   +13 more
core   +1 more source

Optimal Detection of Fusion Pore Dynamics Using Polarized Total Internal Reflection Fluorescence Microscopy

open access: yesFrontiers in Molecular Biosciences, 2021
The fusion pore is the initial narrow connection that forms between fusing membranes. During vesicular release of hormones or neurotransmitters, the nanometer-sized fusion pore may open-close repeatedly (flicker) before resealing or dilating irreversibly,
Joerg Nikolaus   +12 more
doaj   +1 more source

A criterion to identify the equilibration time in lipid bilayer simulations [PDF]

open access: yesPapers in Physics 4, 040005 (2012), 2012
With the aim of establishing a criterion for identifying when a lipid bilayer has reached steady state using the molecular dynamics simulation technique, lipid bilayers of different composition in their liquid crystalline phase were simulated in aqueous solution in presence of CaCl$_2$ as electrolyte, at different concentration levels.
arxiv   +1 more source

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