Results 61 to 70 of about 38,606 (200)

Dual action of BPC194: a membrane active peptide killing bacterial cells. [PDF]

PLoS ONE, 2013
Membrane active peptides can perturb the lipid bilayer in several ways, such as poration and fusion of the target cell membrane, and thereby efficiently kill bacterial cells.
Gemma Moiset, Anna D Cirac, Marc C A Stuart, Siewert-Jan Marrink, Durba Sengupta, Bert Poolman   +5 more
doaj   +1 more source

Lysozyme interaction with negatively charged lipid bilayers: protein aggregation and membrane fusion [PDF]

Soft Matter, 2012
We report on the interaction of hen egg-white lysozyme (HEWL) with lipid vesicles in terms of surface-induced protein conformational variation and subsequent aggregation. In particular, we investigated the variations of the secondary structure of native lysozyme in the presence of liposomes with different surface charge density, resulting from ...
AL KAYAL, TAMER, NAPPINI, SILVIA, RUSSO, EDDA, BERTI, DEBORA, BUCCIANTINI, MONICA, STEFANI, MASSIMO, BAGLIONI, PIERO   +6 more
openaire   +1 more source

Structure and Topology of the Influenza Virus Fusion Peptide in Lipid Bilayers [PDF]

Journal of Biological Chemistry, 1995
The secondary structure of a 20-amino acid length synthetic peptide corresponding to the N terminus of the second subunit of hemagglutinin (HA2) of influenza virus A/PR8/34 and its interaction with phospholipid bilayers are investigated using ESR, Fourier transform infrared (FTIR), and CD spectroscopy.
Lüneberg, J, Martin, Isabelle, Nüssler, F, Ruysschaert, Jean Marie, Herrmann, A.   +4 more
openaire   +2 more sources

Plasticity of Influenza Haemagglutinin Fusion Peptides and Their Interaction with Lipid Bilayers [PDF]

Biophysical Journal, 2005
A detailed molecular dynamics study of the haemagglutinin fusion peptide (N-terminal 20 residues of the HA2 subunits) in a model bilayer has yielded useful information about the molecular interactions leading to insertion into the lipids. Simulations were performed on the native sequence, as well as a number of mutant sequences, which are either ...
Vaccaro, Loredana, Cross, Karen, Kleinjung, Jens, Strauss, Suzana, Thomas, David, Warthon, Stephen, Skehel, John, Fraternali, Franca   +7 more
openaire   +3 more sources

A novel technique using hydrophilic polymers to promote axonal fusion

Neural Regeneration Research, 2016
The management of traumatic peripheral nerve injury remains a considerable concern for clinicians. With minimal innovations in surgical technique and a limited number of specialists trained to treat peripheral nerve injury, outcomes of surgical ...
Ravinder Bamba, D Colton Riley, Nathaniel D Kelm, Mark D Does, Richard D Dortch, Wesley P Thayer   +5 more
doaj   +1 more source

Implicit solvent systematic coarse-graining of dioleoylphosphatidylethanolamine lipids: From the inverted hexagonal to the bilayer structure.

PLoS ONE, 2019
Lamellar and hexagonal lipid structures are of particular importance in the biological processes such as membrane fusion and budding. Atomistic simulations of formation of these phases and transitions between them are computationally prohibitive, hence ...
Saeed Mortezazadeh, Yousef Jamali, Hossein Naderi-Manesh, Alexander P Lyubartsev   +3 more
doaj   +1 more source

Phospholipid - from Model Membrane to Industrial Application

CHIMIA, 1985
The phospholipid bilayer has been shown to be a fundamental, structural element of biological membranes. An attempt is made here to briefly summarize the main physico-chemical properties of phospholipids necessary to understand their functional role in ...
Helmut Hauser
doaj   +1 more source

Intracellular Vesicle Fusion Requires a Membrane-Destabilizing Peptide Located at the Juxtamembrane Region of the v-SNARE

Cell Reports, 2019
Summary: Intracellular vesicle fusion is mediated by soluble N-ethylmaleimide sensitive factor attachment protein receptors (SNAREs) and Sec1/Munc18 (SM) proteins. It is generally accepted that membrane fusion occurs when the vesicle and target membranes
Shailendra S. Rathore, Yinghui Liu, Haijia Yu, Chun Wan, MyeongSeon Lee, Qian Yin, Michael H.B. Stowell, Jingshi Shen   +7 more
doaj   +1 more source

Large Nanodiscs: A Potential Game Changer in Structural Biology of Membrane Protein Complexes and Virus Entry

Frontiers in Bioengineering and Biotechnology, 2020
Phospho-lipid bilayer nanodiscs have gathered much scientific interest as a stable and tunable membrane mimetic for the study of membrane proteins. Until recently the size of the nanodiscs that could be produced was limited to ~ 16 nm. Recent advances in
Krishna M. Padmanabha Das, Krishna M. Padmanabha Das, William M. Shih, William M. Shih, Gerhard Wagner, Mahmoud L. Nasr   +5 more
doaj   +1 more source

Strain-promoted cycloadditions in lipid bilayers triggered by liposome fusion

, 2023
Due to the variety of roles served by the cell membrane, its composition and structure are complex, making it difficult to study. Bioorthogonal reactions, such as the strain promoted azide–alkyne cycloaddition (SPAAC), are powerful tools for exploring the function of biomolecules in their native environment but have been largely unexplored within the ...
Coline Jumeaux, Christopher Spicer, Patrick Charchar, Philip Howes, Margaret Holme, Li Ma, Nicholas Rose, Harunur Rashid, Irene Yarovsky, Molly Stevens   +9 more
openaire   +1 more source