Results 51 to 60 of about 630,739 (251)

Coarse-grained simulation of transmembrane peptides in the gel phase [PDF]

open access: yes, 2013
We use Dissipative Particle Dynamics simulations, combined with parallel tempering and umbrella sampling, to investigate the potential of mean force between model transmembrane peptides in the various phases of a lipid bilayer, including the low ...
Allen, Michael P.   +6 more
core   +1 more source

Light Scattering By Optically-Trapped Vesicles Affords Unprecedented Temporal Resolution Of Lipid-Raft Dynamics

open access: yesScientific Reports, 2017
A spectroscopic technique is presented that is able to identify rapid changes in the bending modulus and fluidity of vesicle lipid bilayers on the micrometer scale, and distinguish between the presence and absence of heterogeneities in lipid-packing ...
Liam Collard   +6 more
doaj   +1 more source

Brownian Motion at Lipid Membranes: A Comparison of Hydrodynamic Models Describing and Experiments Quantifying Diffusion within Lipid Bilayers

open access: yesBiomolecules, 2018
The capability of lipid bilayers to exhibit fluid-phase behavior is a fascinating property, which enables, for example, membrane-associated components, such as lipids (domains) and transmembrane proteins, to diffuse within the membrane.
Stephan Block
doaj   +1 more source

Lipids modulate the increase of BK channel calcium sensitivity by the β1 subunit. [PDF]

open access: yesPLoS ONE, 2014
Co-expression of the auxiliary β1 subunit with the pore forming α subunit of BK dramatically alters apparent calcium sensitivity. Investigation of the mechanism underlying the increase in calcium sensitivity of BK in smooth muscle has concentrated on the
Chunbo Yuan   +3 more
doaj   +1 more source

Quantifying intermolecular interactions as a basis of domain formation in membranes [PDF]

open access: yes, 2006
Within the last two decades the field of membrane biology has witnessed an increased interest in the function and organization of membrane lipids with a particular focus on the possibility of these to demix into separate domains.
Tsamaloukas, Alekos D.
core   +1 more source

Penetration of HIV-1 Tat47–57 into PC/PE Bilayers Assessed by MD Simulation and X-ray Scattering

open access: yesMembranes, 2015
The interactions of the basic, cell-penetrating region (Y47GRKKRRQRRR57) of the HIV-1 Tat protein with dioleoylphosphatidylcholine (DOPC) bilayers were previously assessed by comparing experimental X-ray diffuse scattering with atomistic molecular ...
Chris Neale   +3 more
doaj   +1 more source

Micromachined glass apertures for artificial lipid bilayer formation in a microfluidic system [PDF]

open access: yes, 1998
The use of spark assisted chemical engraving (SACE) to produce glass apertures that are suitable for the formation of artificial bilayer lipid membranes is described.
Uttamchandani, D.G.   +288 more
core   +2 more sources

Strain-promoted cycloadditions in lipid bilayers triggered by liposome fusion [PDF]

open access: yes, 2023
Due to the variety of roles served by the cell membrane, its composition and structure are complex, making it difficult to study. Bioorthogonal reactions, such as the strain promoted azide–alkyne cycloaddition (SPAAC), are powerful tools for exploring ...
Patrick, Charchar   +9 more
core   +2 more sources

Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling. [PDF]

open access: yes, 2011
Transmembrane α-helices play a key role in many receptors, transmitting a signal from one side to the other of the lipid bilayer membrane. Bacterial chemoreceptors are one of the best studied such systems, with a wealth of biophysical and mutational data
Judith P Armitage   +12 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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