Results 111 to 120 of about 1,416,231 (245)
Influence of process variables on the properties of simvastatin self-emulsifying granules obtained through high shear wet granulation [PDF]
, 2015 Improvements of the oral bioavailability of lipophilic drugs can be obtained using lipidic formulations such as the self-emulsifying drug delivery systems.
Benda L. +5 more
core +1 more source
PLoS Pathogens, 2018 Lipid droplet (LD) formation occurs during infection of macrophages with numerous intracellular pathogens, including Mycobacterium tuberculosis. It is believed that M.
M. Knight +4 more
semanticscholar +1 more source
Caenorhabditis elegans DBL-1/BMP Regulates Lipid Accumulation via Interaction with Insulin Signaling
G3: Genes, Genomes, Genetics, 2018 Metabolic homeostasis is coordinately controlled by diverse inputs. Understanding these regulatory networks is vital to combating metabolic disorders. The nematode Caenorhabditis elegans has emerged as a powerful, genetically tractable model system for ...
James F. Clark +4 more
doaj +1 more source
Fluorescent visualization of a spreading surfactant
, 2010 The spreading of surfactants on thin films is an industrially and medically important phenomenon, but the dynamics are highly nonlinear and visualization of the surfactant dynamics has been a long-standing experimental challenge.
Adele M Lichtenberger +6 more
core +1 more source
Ferritin in the fungus Phycomyces [PDF]
, 1971 The iron-protein ferritin has been purified from mycelium, sporangiophores, and spores of the fungus Phycomyces blakesleeanus. It has a protein-to-iron ratio of 5, a sedimentation coefficient of 55S, a buoyant density in CsCl of 1.82 g/cm3, and the ...
David, Charles N., Easterbrook, Kenneth
core +4 more sources
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
Nature Communications, 2018 Nascent lipid droplet (LD) formation occurs in the endoplasmic reticulum (ER) membrane but it is not known how sites of biogenesis are determined. We previously identified ER domains in S. cerevisiae containing the reticulon homology domain (RHD) protein
Amit S. Joshi +6 more
semanticscholar +1 more source
Pex3 promotes formation of peroxisome-peroxisome and peroxisome-lipid droplet contact sites
Scientific ReportsPeroxisomes are ubiquitous organelles that mediate central metabolic functions, such as fatty acid β-oxidation, as well as diverse tissue- and organism-specific processes.
Lucía Amado +9 more
doaj +1 more source
Cryo–electron microscopy structure of the lipid droplet–formation protein seipin
bioRxiv, 2018 Sui et al. report the cryo-EM structure of the conserved luminal domain of the lipid droplet (LD)-formation protein seipin. The structure reveals key features of this domain and suggest a new model for seipin’s role in LD formation.
X. Sui +8 more
semanticscholar +1 more source
Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress [PDF]
, 2018 Aim. Nonalcoholic steatohepatitis (NASH) is the consequence of insulin resistance, fatty acid accumulation, oxidative stress, and lipotoxicity.We hypothesize that an increase in the inflammatory adipokine NOV decreases antioxidant Heme Oxygenase 1 (HO- 1)
Abraham, Nader G. +13 more
core +1 more source