Effect of substrates on the cyclic AMP-dependent lipolytic reaction of hormone-sensitive lipase.
Journal of Lipid Research, 1994 Cyclic AMP-dependent activation of hormone-sensitive lipase (HSL) stimulated lipolysis of [3H]triolein emulsified with gum arabic, but not that of endogenous lipid droplets from rat fat cells.
H Okuda, C Morimoto, T Tsujita
doaj +1 more source
Hepatitis C virus budding at lipid droplet-associated ER membrane visualized by 3D electron microscopy. [PDF]
, 2008 The original publication is available at www.springerlink.comInternational audienceThe mechanisms underlying hepatitis C virus (HCV) morphogenesis remain elusive, but lipid droplets have recently been shown to be important organelles for virus production.
Blanchard, Emmanuelle +3 more
core +3 more sources
Lipid droplets and the host–pathogen dynamic: FATal attraction?
Journal of Cell Biology, 2021 Bosch et al. discuss the role of lipid droplets as a front-line defense in the immune system.
M. Bosch, M. Sweet, R. Parton, A. Pol
semanticscholar +1 more source
Cell, 2009 Lipid droplets (LDs) are universal cellular organelles that specialize in the storage of neutral lipids, such as sterol esters and triacylglycerols (see Essay by Farese and Walther, this issue). As such, they provide the main cellular reservoir for lipids of energy storage and membrane synthesis, and they protect cells from the lipotoxic effects of ...
Krahmer, N. +3 more
openaire +3 more sources
Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes.
Journal of Lipid Research, 1995 Immunocytochemistry was used to determine the intracellular location of perilipins in adipocytes and the occurrence of these proteins in tissues involved in triacylglycerol metabolism.
E.J. Blanchette-Mackie +8 more
doaj +1 more source
Microsomal Triglyceride Transfer Protein (MTP) Associates with Cytosolic Lipid Droplets in 3T3-L1 Adipocytes. [PDF]
PLoS ONE, 2015 Lipid droplets are intracellular energy storage organelles composed of a hydrophobic core of neutral lipid, surrounded by a monolayer of phospholipid and a diverse array of proteins.
Joseph D Love +7 more
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Optimizing adipogenic transdifferentiation of bovine mesenchymal stem cells: a prominent role of ascorbic acid in FABP4 induction [PDF]
, 2020 Adipocyte differentiation of bovine adipose-derived stem cells (ASC) was induced by foetal bovine serum (FBS), biotin, pantothenic acid, insulin, rosiglitazone, dexamethasone and 3-isobutyl-1-methylxanthine, followed by incubation in different media to ...
Aschenbach, Jörg R. +6 more
core +1 more source
Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense
Science, 2020 Cells drop a bomb on pathogens Lipid droplets (LDs) accumulate in cells to serve as lipid storage organelles. They are also an attractive source of nutrients for many pathogens. Bosch et al.
M. Bosch +26 more
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Pathophysiology of Lipid Droplets in Neuroglia
Antioxidants, 2021 In recent years, increasing evidence regarding the functional importance of lipid droplets (LDs), cytoplasmic storage organelles in the central nervous system (CNS), has emerged.
T. Smolič, R. Zorec, N. Vardjan
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Lipid droplets as endogenous intracellular microlenses
Light: Science & Applications, 2021 Using a single biological element as a photonic component with well-defined features has become a new intriguing paradigm in biophotonics. Here we show that endogenous lipid droplets in the mature adipose cells can behave as fully biocompatible ...
Xixi Chen +8 more
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