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Lipid droplets control mitogenic lipid mediator production in human cancer cells [PDF]

open access: yesMolecular Metabolism, 2023
Objectives: Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids and precursors of oxygenated lipid mediators with diverse functions, including the control of cell growth, inflammation and tumourigenesis.
Eva Jarc Jovičić   +13 more
doaj   +4 more sources

Sex Hormone–Dependent Lipid Mediator Formation in Male and Female Mice During Peritonitis [PDF]

open access: yesFrontiers in Pharmacology, 2022
Introduction: Sex differences in inflammation are obvious and contribute to divergences in the incidence and severity of inflammation-related diseases that frequently preponderate in women. Lipid mediators (LMs), mainly produced by lipoxygenase (LOX) and
Fabiana Troisi   +10 more
doaj   +4 more sources

Distinct immune profiles of HIV‐infected subjects are linked to specific lipid mediator signature [PDF]

open access: yesImmunity, Inflammation and Disease, 2022
Introduction: To date, with no prophylactic human immunodeficiency virus (HIV) vaccine available, HIV incidence rates remain undefeated. Despite full virological suppression, HIV+ individuals exhibit a higher rate of cardiovascular disorders and cancers ...
Magdalena Sips   +6 more
doaj   +2 more sources

From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution

open access: yesActa Pharmaceutica Sinica B, 2021
Chronic inflammation results from excessive pro-inflammatory signaling and the failure to resolve the inflammatory reaction. Lipid mediators orchestrate both the initiation and resolution of inflammation.
Tran Thi Van Anh   +17 more
doaj   +3 more sources

Effects of flaxseed supplementation on omega-6 to omega-3 fatty acid ratio, lipid mediator profile, proinflammatory cytokines and stress indices in laying hens

open access: yesJournal of Applied Animal Research, 2021
Although polyunsaturated fatty acids (PUFAs) have gained attention because of their physiological effects on inflammation and stress, their derivatives, termed lipid mediators, have been rarely examined, especially in laying hens. In this study, we aimed
Sang-Mok Lee   +8 more
doaj   +2 more sources

The Lipid Mediator Resolvin D1 Reduces the Skin Inflammation and Oxidative Stress Induced by UV Irradiation in Hairless Mice

open access: yesFrontiers in Pharmacology, 2018
UV irradiation-induced oxidative stress and inflammation contribute to the development of skin diseases. Therefore, targeting oxidative stress and inflammation might contribute to reduce skin diseases.
Priscila Saito   +12 more
doaj   +3 more sources

Phytochemical Characterization of Cannabis sativa L. Chemotype V Reveals Three New Dihydrophenanthrenoids That Favorably Reprogram Lipid Mediator Biosynthesis in Macrophages [PDF]

open access: yesPlants, 2022
The growing general interest surrounding Cannabis sativa L. has led to a renewal in breeding and resulted in an impressive variability of chemotypical characteristics that required the division of cannabis into different recognized chemotypes.
Stefano Salamone   +6 more
doaj   +2 more sources

The impact of the soluble epoxide hydrolase cascade on periodontal tissues

open access: yesFrontiers in Dental Medicine, 2023
Periodontitis is a chronic inflammatory disease with complex pathogenesis. Uncontrolled inflammation is driven by the immune system in response to accumulation of oral biofilm that leads to alveolar bone loss, bleeding, increased periodontal probing ...
Henrique Ballassini Abdalla   +2 more
doaj   +1 more source

Bioactive lipids as biomarkers of adverse reactions associated with apheresis platelet concentrate transfusion

open access: yesFrontiers in Immunology, 2023
Platelet concentrate (PC) transfusion seeks to provide haemostasis in patients presenting severe central thrombocytopenia or severe bleeding. PCs may induce adverse reactions (AR) that can occasionally be severe (SAR).
Anne-Claire Duchez   +25 more
doaj   +1 more source

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