Energetics of lipid bilayers with applications to deformations induced by inclusions [PDF]
A new energy for the description of large deformations of lipid bilayers is formulated with mathematical rigor. This energy is derived by considering the smectic A liquid crystalline nature of lipid bilayers and the coupling between the deformations of ...
De Vita, R., Stewart, Iain W.
core +4 more sources
Omega-3 Polyunsaturated Fatty Acids and the Intestinal Epithelium—A Review
Epithelial cells (enterocytes) form part of the intestinal barrier, the largest human interface between the internal and external environments, and responsible for maintaining regulated intestinal absorption and immunological control.
Luke A. Durkin +2 more
doaj +1 more source
Lipid Mediators in Inflammatory Disorders [PDF]
During the past few decades, intensive collaborative research in the fields of chronic and acute inflammatory disorders has resulted in a better understanding of the pathophysiology and diagnosis of these diseases. Modern therapeutic approaches are still not satisfactory and shock, sepsis and multiple organ failure remain the great challenge in ...
Heller, Axel R. +3 more
openaire +3 more sources
Regulatory Roles of Phospholipase A2 Enzymes and Bioactive Lipids in Mast Cell Biology
Lipids play fundamental roles in life as an essential component of cell membranes, as a major source of energy, as a body surface barrier, and as signaling molecules that transmit intracellular and intercellular signals.
Yoshitaka Taketomi, Makoto Murakami
doaj +1 more source
Arachidonate 15-lipoxygenase type B: Regulation, function, and its role in pathophysiology
As a lipoxygenase (LOX), arachidonate 15-lipoxygenase type B (ALOX15B) peroxidizes polyenoic fatty acids (PUFAs) including arachidonic acid (AA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and linoleic acid (LA) to their corresponding fatty
Yvonne Benatzy +5 more
doaj +1 more source
Periodontitis is a chronic inflammatory disease induced by dysbiotic dental biofilms. Management of periodontitis is primarily anti-bacterial via mechanical removal of bacterial biofilm.
Chun-Teh Lee, Gena D. Tribble
doaj +1 more source
Lipid droplets and lipid mediators in viral infection and immunity [PDF]
AbstractLipid droplets (LDs) contribute to key pathways important for the physiology and pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids, protein sequestration, removal of toxic lipids and cellular communication; however, recent advancements in the field show these organelles as essential for various cellular
Ebony A Monson +4 more
openaire +3 more sources
Pro-Resolving Mediators in Regulating and Conferring Macrophage Function
Macrophages are central in coordinating the host response to both sterile and infective insults. Clearance of apoptotic cells and cellular debris is a key biological action preformed by macrophages that paves the way to the resolution of local ...
Jesmond Dalli, Charles N. Serhan
doaj +1 more source
Synthesis, Structural Confirmation, and Biosynthesis of 22-OH-PD1n-3 DPA
PD1n-3 DPA belongs to the protectin family of specialized pro-resolving lipid mediators. The protectins are endogenously formed mediators that display potent anti-inflammatory properties and pro-resolving bioactivities and have attracted interest in drug
Jannicke Irina Nesman +5 more
doaj +1 more source
Associations between Plasma Lipid Mediators and Chronic Daily Headache Outcomes in Patients Randomized to a Low Linoleic Acid Diet with or without Added Omega-3 Fatty Acids [PDF]
A previous report showed that 12-week lowering of dietary omega-6 linoleic acid (LA) coupled with increased omega-3 polyunsaturated fatty acid (PUFA) intake (H3-L6 diet) reduced headache frequency and improved quality of life in patients with chronic ...
Faurot, Keturah R +19 more
core +1 more source

