Results 31 to 40 of about 926,787 (298)
The Peroxisome Proliferator-activated Receptor γ (PPARγ) Controls Natural Protective Mechanisms against Lipid Peroxidation in Amyotrophic Lateral Sclerosis [PDF]
, 2012 Recent evidence highlights the peroxisome proliferator-activated receptors (PPARs) as critical neuroprotective factors in several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). To gain new mechanistic insights into the role of
Maggi, Adriana +8 more
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Frontiers in Immunology, 2022 BackgroundNeuroinflammatory response contributes to early neurological deterioration (END) and unfavorable long-term functional outcome in patients with acute ischemic stroke (AIS) who recanalized successfully by endovascular thrombectomy (EVT), but ...
Jiheng Hao +20 more
doaj +1 more source
Lipid metabolism and HCV infection [PDF]
, 2010 Chronic infection by hepatitis C virus (HCV) can lead to severe liver disease and is a global healthcare problem. The liver is highly metabolically active and one of its key functions is to control the balance of lipid throughout the body.
Boulant, Steeve +11 more
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Frontiers in Immunology, 2021 The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation via their roles in ...
Stephania Libreros +6 more
doaj +1 more source
Maresin 1 repletion improves muscle regeneration after volumetric muscle loss
eLife, 2023 The acute traumatic or surgical loss of skeletal muscle, known as volumetric muscle loss (VML), is a devastating type of injury that results in exacerbated and persistent inflammation followed by fibrosis.
Jesus A Castor-Macias +12 more
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Understanding the connection between platelet-activating factor, a UV-induced lipid mediator of inflammation, immune suppression and skin cancer. [PDF]
, 2016 Lipid mediators of inflammation play important roles in several diseases including skin cancer, the most prevalent type of cancer found in the industrialized world.
Ullrich, S. E., DAMIANI, Elisabetta
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Molecules, 2023 Intense exposure to UVB radiation incites excessive production of reactive oxygen species (ROS) and inflammation. The resolution of inflammation is an active process orchestrated by a family of lipid molecules that includes AT-RvD1, a specialized ...
Cristina P. B. Melo +12 more
doaj +1 more source
Lipid mediators and allergic diseases [PDF]
Annals of Allergy, Asthma & Immunology, 2013 To review the basic science and translational relevance of lipid mediators in the pathobiology of allergic diseases.PubMed was searched for articles using the key terms lipid mediator, prostaglandin, prostanoid, leukotriene, thromboxane, asthma, and allergic inflammation.Articles were selected based on their relevance to the goals of this review ...
Laura B, Fanning, Joshua A, Boyce
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Fracture healing and lipid mediators [PDF]
BoneKEy Reports, 2014 Lipid mediators regulate bone regeneration during fracture healing. Prostaglandins and leukotrienes are well-known lipid mediators that regulate inflammation and are synthesized from the Ω-6 fatty acid, arachidonic acid. Cyclooxygenase (COX-1 or COX-2) and 5-lipoxygenase (5-LO) catalyze the initial enzymatic steps in the synthesis of prostaglandins and
J Patrick, O'Connor +3 more
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Hyperoxic Exposure Caused Lung Lipid Compositional Changes in Neonatal Mice
, 2020 Treatments with supplemental oxygen in premature infants can impair lung development, leading to bronchopulmonary dysplasia (BPD). Although a stage-specific alteration of lung lipidome occurs during postnatal lung development, whether neonatal hyperoxia,
Hongwei Yao +4 more
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