Results 41 to 50 of about 333,930 (355)
Spartin-mediated lipid transfer facilitates lipid droplet turnover
Proceedings of the National Academy of Sciences, 2023 AbstractLipid droplets (LDs) are organelles critical for energy storage and membrane lipid homeostasis, whose number and size are carefully regulated in response to cellular conditions. The molecular mechanisms underlying lipid droplet biogenesis and degradation, however, are not well understood.
Neng Wan +6 more
openaire +3 more sources
Occurrence and biological activity of palmitoleic acid isomers in phagocytic cells
Journal of Lipid Research, 2018 Recent studies have highlighted the role of palmitoleic acid [16:1n-7 (cis-9-hexadecenoic acid)] as a lipid hormone that coordinates cross-talk between liver and adipose tissue and exerts anti-inflammatory protective effects on hepatic steatosis and ...
Alma M. Astudillo +6 more
doaj +1 more source
Temperature and time-dependent effects of delayed blood processing on oxylipin concentrations in human plasma. [PDF]
, 2019 BACKGROUND:Oxidized derivatives of polyunsaturated fatty acids, collectively known as oxylipins, are labile bioactive mediators with diverse roles in human physiology and pathology.
Gibson, Robert A +8 more
core +1 more source
Journal of Applied Animal Research, 2021 Although polyunsaturated fatty acids (PUFAs) have gained attention because of their physiological effects on inflammation and stress, their derivatives, termed lipid mediators, have been rarely examined, especially in laying hens. In this study, we aimed
Sang-Mok Lee +8 more
doaj +1 more source
Fracture healing and lipid mediators [PDF]
BoneKEy Reports, 2014 Lipid mediators regulate bone regeneration during fracture healing. Prostaglandins and leukotrienes are well-known lipid mediators that regulate inflammation and are synthesized from the Ω-6 fatty acid, arachidonic acid. Cyclooxygenase (COX-1 or COX-2) and 5-lipoxygenase (5-LO) catalyze the initial enzymatic steps in the synthesis of prostaglandins and
J Patrick, O'Connor +3 more
openaire +2 more sources
The ethanolamide metabolite of DHA, docosahexaenoylethanolamine, shows immunomodulating effects in mouse peritoneal and RAW264.7 macrophages: evidence for a new link between fish oil and inflammation [PDF]
, 2011 Several mechanisms have been proposed for the positive health effects associated with dietary consumption of long-chain n-3 PUFA (n-3 LC-PUFA) including DHA (22 : 6n-3) and EPA (20 : 5n-3).
Attya, M. +8 more
core +3 more sources
Lipid mediators and allergic diseases [PDF]
Annals of Allergy, Asthma & Immunology, 2013 To review the basic science and translational relevance of lipid mediators in the pathobiology of allergic diseases.PubMed was searched for articles using the key terms lipid mediator, prostaglandin, prostanoid, leukotriene, thromboxane, asthma, and allergic inflammation.Articles were selected based on their relevance to the goals of this review ...
Laura B, Fanning, Joshua A, Boyce
openaire +2 more sources
Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients [PDF]
, 2008 Introduction: Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood.
Behrendt, Heidrun +7 more
core +2 more sources
Lipid mediators in diabetic nephropathy [PDF]
Fibrogenesis & Tissue Repair, 2014 The implications of lipid lowering drugs in the treatment of diabetic nephropathy have been considered. At the same time, the clinical efficacy of lipid lowering drugs has resulted in improvement in the cardiovascular functions of chronic kidney disease (CKD) patients with or without diabetes, but no remarkable improvement has been observed in the ...
Srivastava, Swayam +3 more
openaire +2 more sources
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source