Results 11 to 20 of about 47,375 (257)

Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila

iScience, 2021
Summary: The endoplasmic reticulum (ER)-resident transmembrane protein kinase/RNase Ire1 is a conserved sensor of the cellular unfolded protein response and has been implicated in lipid homeostasis, including lipid synthesis and transport, across species.
Peng Zhao, Ping Huang, Tongfu Xu, Xiaoxiang Xiang, Ying Sun, Jingqi Liu, Cheng Yan, Lei Wang, Jiamei Gao, Shang Cui, Xiangdong Wang, Lixing Zhan, Haiyun Song, Jingnan Liu, Wei Song, Yong Liu   +15 more
doaj   +1 more source

Activated autophagy-lysosomal pathway in dairy cows with hyperketonemia is associated with lipolysis of adipose tissues

Journal of Dairy Science, 2022
: Activated autophagy-lysosomal pathway (ALP) can degrade virtually all kinds of cellular components, including intracellular lipid droplets, especially during catabolic conditions.
Hao Yu, Minghe Fan, Xiying Chen, Xiuhuan Jiang, Juan J. Loor, Ahmad Aboragah, Cai Zhang, Hongxu Bai, Zhiyuan Fang, Taiyu Shen, Zhe Wang, Yuxiang Song, Xinwei Li, Guowen Liu, Xiaobing Li, Xiliang Du   +15 more
doaj   +1 more source

Genome-wide exploration of the GDSL-type esterase/lipase gene family in rapeseed reveals several BnGELP proteins active during early seedling development

Frontiers in Plant Science, 2023
The Gly-Asp-Ser-Leu (GDSL)-type esterase/lipase proteins (GELP) are one of the most important families of lipolytic enzymes and play prominent roles in seed germination and early seedling establishment through mobilizing the lipids stored in seeds ...
Yahui Ding, Liwen Xing, Jiamin Xu, Teng Jiang, Xiuhua Tang, Yaxuan Wang, Shuhua Huang, Wenfang Hao, Xiaona Zhou, Yanfeng Zhang, Chang Gen Xie   +10 more
doaj   +1 more source

Mobilization of Storage Reserves in Dalbergia spruceana Benth. (Fabaceae) Seeds During Germination at Different Temperatures

Floresta e Ambiente, 2023
Temperature may affect the mobilization and hydrolysis of storage reserves for energy production during seed germination. This study investigated germination performance and reserve mobilization in Dalbergia spruceana Benth.
Clenes Cunha Lima, Eduardo Euclydes Lima Borge, Ely Simone Cajueiro Gurgel   +2 more
doaj   +1 more source

Primary Tumor Fluorine‐18 Fluorodeoxydglucose (18F‐FDG) Is Associated With Cancer-Associated Weight Loss in Non-Small Cell Lung Cancer (NSCLC) and Portends Worse Survival

Frontiers in Oncology, 2022
AimTo investigate the diagnostic potential of and associations between tumor 18F‐FDG uptake on PET imaging and cancer-associated weight loss.Methods774 non-small cell lung cancer (NSCLC) patients with pre-treatment PET evaluated between 2006 and 2014 ...
Santiago Olaechea, Bhavani S. Gannavarapu, Christian Alvarez, Anne Gilmore, Brandon Sarver, Donglu Xie, Rodney Infante, Puneeth Iyengar   +7 more
doaj   +1 more source

Tumor necrosis factor-α promotes lipolysis and reduces insulin sensitivity by activating nuclear factor kappa B and c-Jun N-terminal kinase in primary bovine adipocytes

Journal of Dairy Science, 2022
: Sustained lipolysis and insulin resistance increase the risk of metabolic dysfunction in dairy cows during the transition period. Proinflammatory cytokines are key regulators of adipose tissue metabolism in nonruminants, but biological functions of ...
Xiliang Du, Mingchao Liu, Wenjun Tai, Hao Yu, Xue Hao, Juan J. Loor, Qianming Jiang, Zhiyuan Fang, Xinxing Gao, Minghe Fan, Wenwen Gao, Lin Lei, Yuxiang Song, Zhe Wang, Cai Zhang, Guowen Liu, Xinwei Li   +16 more
doaj   +1 more source

Fatty Acid Profiles of Serum Lipid Fractions Change Minimally in Sled Dogs Before and After Short Bouts of Exercise

Frontiers in Veterinary Science, 2021
Although emerging data suggests a greater influence of gluconeogenic precursors, endurance sled dogs have long appeared to rely heavily on fatty acid oxidation for sustained energy production. However, much of the research investigating lipid utilization
James R. Templeman, Luciano Trevizan, David W. L. Ma, Anna K. Shoveller   +3 more
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Mobilization efficiency is critically regulated by fat via marrow PPARδ

Haematologica, 2021
The mobilization efficiency of hematopoietic stem/progenitor cells from bone marrow (BM) to circulation by granulocyte colony-stimulating factor (G-CSF) is dramatically dispersed in humans and mice with no mechanistic lead for poor mobilizers.
Tomohide Suzuki, Shinichi Ishii, Masakazu Shinohara, Yuko Kawano, Kanako Wakahashi, Hiroki Kawano, Akiko Sada, Kentaro Minagawa, Michito Hamada, Satoru Takahashi, Tomoyuki Furuyashiki, Nguan Soon Tan, Toshimitsu Matsui, Yoshio Katayama   +13 more
doaj   +1 more source

Early effects of feeding excess vitamin A: mechanism of fatty liver production in rats

Journal of Lipid Research, 1969
Oral administration of vitamin A (30,000 IU daily for 2 days) to young rats caused a marked increase in hepatic glycogen, cholesterol, and glycerides, while hepatic phospholipid content remained almost unaltered.In an examination of the pathogenesis of ...
Vishwa Nath Singh, Malathy Singh, T.A. Venkitasubramanian   +2 more
doaj   +1 more source

Diacylglycerol transport in the insect fat body: evidence of involvement of lipid droplets and the cytosolic fraction

Journal of Lipid Research, 2001
In this report we show the existence of a distinct pool of fat body diacylglycerol (DG) that can be distinguished from the bulk DG. This is a dynamic pool of DG that uses FA entering the fat body from the hemolymph, whereas the bulk DG uses the fatty ...
Estela L. Arrese, Justin L. Gazard, Matthew T. Flowers, Jose L. Soulages, Michael A. Wells   +4 more
doaj   +1 more source