Exploration of bivalent ligands targeting putative mu opioid receptor and chemokine receptor CCR5 dimerization [PDF]
, 2016 Modern antiretroviral therapies have provided HIV-1 infected patients longer lifespans and better quality of life. However, several neurological complications are now being seen in these patients due to HIV-1 associated injury of neurons by infected ...
Arnatt, Christopher K. +10 more
core +2 more sources
Safety Aspects of Iron in Food [PDF]
, 2001 During the last decades efforts regarding dietary iron supply focused mostly on the prevention of deficiencies, especially during growth and pregnancy.
Schümann, Klaus
core +1 more source
Lipid Mobilizer Hormone in Triton Hyperlipemia.
Experimental Biology and Medicine, 1967 SummaryTests were performed on baseline and periodic blood samples obtained from rabbits treated with intramuscular injections of Triton WR-1339. The ensuing hyper-lipemia was characterized by marked elevation in total fatty acids, triglycerides, cholesterol, lipid phosphorus, and total lipids. Paper electrophoresis revealed a concomitant increase in β-
C J, Zarafonetis, G L, Brody, L, Dabich
openaire +2 more sources
ACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins
Journal of Lipid Research, 2007 Previous studies in nonhuman primates revealed a striking positive correlation between liver cholesteryl ester (CE) secretion rate and the development of coronary artery atherosclerosis.
Ryan E. Temel +3 more
doaj +1 more source
Alzheimer’s disease-associated peptide Aβ42 mobilizes ER Ca2+ via InsP3R-dependent and -independent mechanisms [PDF]
, 2013 Dysregulation of Ca2+ homeostasis is considered to contribute to the toxic action of the Alzheimer’s Disease (AD) associated Amyloid β-peptide (Aβ). Ca2+ fluxes across the plasma membrane and release from intracellular stores have both been reported to ...
Amijee, Hozeefa +5 more
core +3 more sources
, 2017 How does a mother supply a key building block of the brain required for neurodevelopment to her fetus in pregnancy? The critical requirement of docosahexaenoic acid (DHA) for fetal brain development, and the poor efficiency of its synthesis in humans, is
Freeman, Dilys J., Meyer, Barbara J.
core
Metabolic interactions between vitamin A and conjugated linoleic acid [PDF]
, 2014 Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner.
BANNI, SEBASTIANO +7 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Complex Interplay of Insulin Resistance and Metabolic Inflammation in Transition Dairy Cows
AnimalsDuring the transition period, dairy cows exhibit heightened energy requirements to sustain fetal growth and lactogenesis. The mammary gland and the growing fetus increase their demand for glucose, leading to the mobilization of lipids to support the ...
Kaixi Qiao +6 more
doaj +1 more source
Insulin response and changes in composition of non-esterified fatty acids in blood plasma of middle-aged men following isoenergetic fatty and carbohydrate breakfasts [PDF]
, 2000 It was previously shown that a high plasma concentration of non-esterified fatty acids (NEFA) persisted after a fatty breakfast, but not after an isoenergetic carbohydrate breakfast, adversely affecting glucose tolerance.
Carpenter, KLH +5 more
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