Results 51 to 60 of about 1,515,713 (252)

Reconfigurable Au Nanoparticle Monolayers on Regenerated Cellulose Hydrogels: Highly Sensitive SERS Detection of Polystyrene Micro/Nanoplastics With Interpretable Deep Learning

Advanced Functional Materials, EarlyView.
A regenerated cellulose (RC) hydrogel‐based SERS substrate integrating a Marangoni‐transferred gold nanoparticle self‐assembled monolayer (Au‐SAM) is fabricated. Reswelling‐induced hotspot formation enhances polystyrene micro/nanoplastics (PS MNPs) detection in complex matrices, providing reproducible, high‐throughput SERS signals across diverse ...
Youngho Jeon, Yu‐Jin Jeon, Suji Lee, Jeseong Kim, Dae‐Hyun Jung, Jungmok You   +5 more
wiley   +1 more source

Putrescine modulates antioxidant defense response in wheat under high temperature stress

Biologia Plantarum, 2012
Effects of putrescine (Put) on responses of wheat (Triticum aestivum) seedlings or detached tillers at mid-milky stage to high temperature (HT) stress were investigated. The heat tolerant cv.
B. Asthir, A. Koundal, N. S. Bains
doaj   +1 more source

Additional antiepileptic mechanisms of levetiracetam in lithium-pilocarpine treated rats. [PDF]

PLoS ONE, 2013
Several studies have addressed the antiepileptic mechanisms of levetiracetam (LEV); however, its effect on catecholamines and the inflammatory mediators that play a role in epilepsy remain elusive.
Muhammad Y Al-Shorbagy, Bahia M El Sayeh, Dalaal M Abdallah   +2 more
doaj   +1 more source

A Modular Liver–Microbial Microfluidic Platform to Evaluate Therapeutic and Adverse Effects of Microbial Metabolites

Advanced Healthcare Materials, EarlyView.
This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan, In Young Hwang, Nanthini Jayabalan, Hui Ling Lee, Louis Jun Ye Ong, Chwee Teck Lim, Matthew Wook Chang, Yi‐Chin Toh   +7 more
wiley   +1 more source

Ferrostatin-1 inhibits osteoclast differentiation and prevents osteoporosis by suppressing lipid peroxidation

Journal of Orthopaedic Surgery and Research
Background Osteoporosis (OP) is a systemic disease characterized by low bone mass. New progress has been made in the study of OP, such as lipid peroxidation. However, the role of lipid peroxides in osteoclast differentiation is still unclear.
Wenbo Xu, Shiyan Lv, Xiaoyan Wang, Chengchao Song, Chunyang Xi, Jinglong Yan   +5 more
doaj   +1 more source

Circulating Lipid Peroxides Associate with More Aggressive Tumor Phenotypes and Increased Risks of Recurrence and Mortality in Breast Cancer Patients

Medical Sciences
Background/Objectives: Breast cancer is the most common neoplasm among women and remains the leading cause of cancer-related mortality in the female population worldwide.
Julia Fernandes Gois Orrutéa, Rafaela Oliveira Matos, João Paulo Araújo Pinto, André Cherubini Cechinel, Bruna Yukie Koizumi, Rafael Gomes Paz, Rafaella Frederico Almeida, Janaína Carla da Silva, Tatiane Renata Fagundes, Daniel Rech, Guilherme Welter Wendt, Carolina Panis   +11 more
doaj   +1 more source

Lipid peroxides induce expression of catalase in cultured vascular cells

Journal of Lipid Research, 2000
Various forms of oxidized low-density lipoproteins (Ox-LDL) are thought to play a major role in the development of atherosclerosis. The lipid components of Ox-LDL present a plethora of proatherogenic effects in in vitro cell culture systems, suggesting ...
Olivier Meilhac, Mimi Zhou, Nalini Santanam, Sampath Parthasarathy   +3 more
doaj   +1 more source

Macrophage Membrane‐Camouflaged Nanozyme Microneedles Restore Immunovascular Homeostasis Through SPP1‐ApoE Signaling in Diabetic Wounds

Advanced Healthcare Materials, EarlyView.
Macrophage membrane‐coated Cu/Zn‐MOF nanozyme microneedles (MNs) reprogram the diabetic wound microenvironment through localized, minimally invasive delivery. By suppressing M1‐like macrophage activation while promoting extracellular matrix deposition and angiogenesis, this biomimetic platform accelerates diabetic wound repair.
Qipeng Wu, Yuan Xiong, Li Lu, Han Wang, Hui Hu, Mohammad‐Ali Shahbazi, Guohui Liu, Bobin Mi   +7 more
wiley   +1 more source

CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis

Cell Reports
Summary: Ferroptosis is an iron-dependent cell death mechanism characterized by the accumulation of toxic lipid peroxides and cell membrane rupture.
Kamakoti P. Bhat, Jinchu Vijay, Caroline K. Vilas, Jyoti Asundi, Jun Zou, Ted Lau, Xiaoyu Cai, Musaddeque Ahmed, Michal Kabza, Julie Weng, Jean-Philippe Fortin, Aaron Lun, Steffen Durinck, Marc Hafner, Michael R. Costa, Xin Ye   +15 more
doaj   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

Advanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang, Yi‐Ke Lin, Wei‐Li Chen, Ta‐Ching Chen, Jiashing Yu   +4 more
wiley   +1 more source