Measurement of Fe(2+)-induced Lipid Peroxidation of Mitochondria used Thiobarbituric Acid Method under the Acetic Acid Conditions [PDF]
Mitochondrial lipid peroxidations were usually detected by the thiobarbituric acid (TBA) color reaction under the acidic conditions with hydrochloric and trichloroacetic acids. The time response curve of Fe(2+)-induced lipid peroxidation, accompanied the
Yamamoto, Goki
core +1 more source
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti+8 more
wiley +1 more source
Capillary electrophoresis to monitor the oxidative modification of low density lipoproteins
A procedure has been developed that uses high performance capillary electrophoresis to monitor the changes in the electrophoretic mobility of low density lipoproteins (LDL) resulting from Cu2+-catalyzed lipid peroxidation.
Joseph Stocks, Norman E. Miller
doaj +1 more source
Vitamin E requirements of adult domestic cats (Felis catus) fed diets containing high levels of fish oil : a thesis presented in partial fulfilment of the requirement for the degree of Master of Nutritional Sciences at Massey University, Palmerston North, New Zealand [PDF]
The vitamin E (α-tocopherol) requirement of adult cats fed diets containing high levels of fish oil was investigated. Thirty-two (16 male, 16 female) adult domestic cats (Felis catus) were randomly allocated to four groups according to sex and fed one of
Wu, Yuben
core
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley +1 more source
Additional antiepileptic mechanisms of levetiracetam in lithium-pilocarpine treated rats. [PDF]
Several studies have addressed the antiepileptic mechanisms of levetiracetam (LEV); however, its effect on catecholamines and the inflammatory mediators that play a role in epilepsy remain elusive.
Muhammad Y Al-Shorbagy+2 more
doaj +1 more source
Meat and cancer: haemoglobin and haemin in a low calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats [PDF]
High intake of red meat, but not of white meat, is associated with an increased risk of colon cancer. However, red meat does not promote cancer in rodents.
Corpet, Denis E.+4 more
core +4 more sources
ABSTRACT Objective Neurodegeneration with brain iron accumulation (NBIA) comprises rare genetic disorders characterized by predominantly extrapyramidal symptoms and iron deposition in the basal ganglia. Conventional magnetic resonance imaging (MRI) detects qualitative changes but cannot accurately quantify iron accumulation. Quantitative susceptibility
Özge Uygun+21 more
wiley +1 more source
Lipid peroxides induce expression of catalase in cultured vascular cells
Various forms of oxidized low-density lipoproteins (Ox-LDL) are thought to play a major role in the development of atherosclerosis. The lipid components of Ox-LDL present a plethora of proatherogenic effects in in vitro cell culture systems, suggesting ...
Olivier Meilhac+3 more
doaj +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao+10 more
wiley +1 more source