The proppin Bcas3 and its interactor KinkyA localize to the early phagophore and regulate autophagy [PDF]
, 2021 To resolve the signaling mechanisms that mediate the starvation-induced processes of Dictyostelium sporulation and encystation, we performed insertional mutagenesis on cells harboring an mRFP-tagged spore gene.
Schaap, Pauline, Yamada, Yoko
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Effects of Three Lipidated Oxytocin Analogs on Behavioral Deficits in CD38 Knockout Mice
Brain Sciences, 2017 Oxytocin (OT) is a nonapeptide that plays an important role in social behavior. Nasal administration of OT has been shown to improve trust in healthy humans and social interaction in autistic subjects.
Stanislav M. Cherepanov +9 more
doaj +1 more source
Regulation of ERK2 activity by dynamic S-acylation
Cell Reports, 2023 Summary: Extracellular signal-regulated kinases (ERK1/2) are key effector proteins of the mitogen-activated protein kinase pathway, choreographing essential processes of cellular physiology.
Saara-Anne Azizi +3 more
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New developments in probing and targeting protein acylation in malaria, leishmaniasis and African sleeping sickness [PDF]
, 2017 Infections by protozoan parasites, such as Plasmodium falciparum or Leishmania donovani, have a significant health, social and economic impact and threaten billions of people living in tropical and sub-tropical regions of developing countries worldwide ...
EDWARD W. TATE +4 more
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, 2019 Autophagy depends on the E2 enzyme, Atg3, functioning in a conserved E1-E2-E3 trienzyme cascade that catalyzes lipidation of Atg8-family ubiquitin-like proteins (UBLs).
Grace, C. +5 more
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Human ATG3 binding to lipid bilayers: role of lipid geometry, and electric charge [PDF]
, 2017 Specific protein-lipid interactions lead to a gradual recruitment of AuTophaGy-related (ATG) proteins to the nascent membrane during autophagosome (AP) formation.
Alonso Izquierdo, Alicia +5 more
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Real-Time Monitoring of ATG8 Lipidation in vitro Using Fluorescence Spectroscopy
Bio-ProtocolAutophagy is an essential catabolic pathway used to sequester and engulf cytosolic substrates via a unique double-membrane structure, called an autophagosome.
Wenxin Zhang +2 more
doaj +1 more source
How to rewire the host cell: A home improvement guide for intracellular bacteria. [PDF]
, 2017 Intracellular bacterial pathogens have developed versatile strategies to generate niches inside the eukaryotic cells that allow them to survive and proliferate.
Cornejo, Elias +2 more
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Self-assembly, nematic phase formation and organocatalytic behaviour of a proline-functionalized lipopeptide [PDF]
, 2020 The self-assembly of the amphiphilic lipopeptide PAEPKI-C16 (P = proline, A = alanine, E = glutamic acid, K = lysine, I = isoleucine, C16 = hexadecyl) was investigated using a combination of spectroscopic, microscopic and scattering methods and compared ...
Aguilar, Andrea M. +7 more
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Cellular palmitoylation and trafficking of lipidated peptides
Journal of Lipid Research, 2007 Many important signaling proteins require the posttranslational addition of fatty acid chains for their proper subcellular localization and function.
Jeremiah M. Draper +2 more
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