Results 1 to 10 of about 30,733 (194)
Lipidomics unveils the complexity of the lipidome in metabolic diseases [PDF]
Clinical and Translational Medicine, 2018 Dysregulation of lipid metabolism is responsible for pathologies of human diseases including metabolic diseases. Recent advances in lipidomics analysis allow for the targeted and untargeted identification of lipid species and for their quantification in ...
Todd A. Lydic, Young-Hwa Goo
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Clinical lipidomics reveals high individuality and sex specificity of circulatory lipid signatures: a prospective healthy population study [PDF]
Journal of Lipid ResearchLipid metabolism and circulatory lipid levels are tightly associated with the (cardio)metabolic health. Consequently, MS-based lipidomics has emerged as a powerful phenotyping tool in epidemiological, human population, and in clinical intervention ...
Jessica Medina +8 more
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Accurate Quantification of Lipid Species by Electrospray Ionization Mass Spectrometry — Meets a Key Challenge in Lipidomics [PDF]
Metabolites, 2011 Electrospray ionization mass spectrometry (ESI-MS) has become one of the most popular and powerful technologies to identify and quantify individual lipid species in lipidomics. Meanwhile, quantitative analysis of lipid species by ESI-MS has also become a
Kui Yang, Xianlin Han
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Current perspectives for metabolomics and lipidomics in dyslipidemia of acne vulgaris: a mini review [PDF]
Frontiers in MedicineAcne vulgaris (AV) is a common inflammatory disorder involving the pilosebaceous unit. Many studies have reported that people with AV have higher levels of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-c ...
Liang Wu +6 more
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Analytical and Bioanalytical Chemistry, 2015 Profiling of the individual lipids in biological fluids is of great concern with respect to human health and disease; as a consequence, the task of lipid analysis and profiling has become ever increasingly important, and lipidomics has become the target of postgenomic research.
DONATO, Paola Agata Eustochia +4 more
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Evaluation of Normalization Approaches for Quantitative Analysis of Bile Acids in Human Feces
Metabolites, 2022 Quantitative analysis of bile acids in human feces can potentially help to better understand the influence of the gut microbiome and diet on human health.
Hans-Frieder Schött +5 more
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Analytical and Bioanalytical Chemistry, 2018 The state-of-art in the lipidomic analysis is summarized here to provide the overview of available sample preparation strategies, mass spectrometry (MS)-based methods for the qualitative analysis of lipids, and the quantitative MS approaches for high-throughput clinical workflows.
Michal Holčapek +2 more
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Lipidomics of Glycosphingolipids [PDF]
Metabolites, 2012 Glycosphingolipids (GSLs) contain one or more sugars that are attached to a sphingolipid moiety, usually to a ceramide, but in rare cases also to a sphingoid base. A large structural heterogeneity results from differences in number, identity, linkage, and anomeric configuration of the carbohydrate residues, and also from structural differences within ...
Farwanah, Hany, Kolter, Thomas
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Nature Communications, 2023 The circulatory lipidome is a valuable source for disease markers, but reliable marker discovery requires continuous development of lipidomic methods for large-scale clinical profiling.
Raissa Lerner +7 more
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Metabolites, 2021 Cancer metabolism is associated with the enhanced lipogenesis required for rapid growth and proliferation. However, the magnitude of dysregulation of diverse lipid species still requires significant characterization, particularly in ovarian clear cell ...
Sartaj Ahmad Mir +8 more
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