Results 21 to 30 of about 30,733 (194)
The Lipidome Fingerprint of Longevity [PDF]
Molecules, 2020 Lipids were determinants in the appearance and evolution of life. Recent studies disclose the existence of a link between lipids and animal longevity. Findings from both comparative studies and genetics and nutritional interventions in invertebrates, vertebrates, and exceptionally long-lived animal species—humans included—demonstrate that both the cell
Mariona Jové +7 more
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Biomolecules, 2021 Atherosclerosis is the main cause of cardiovascular diseases with high prevalence worldwide. A promising therapeutic strategy to reverse atherosclerotic process is to improve the athero-protective potential of high-density lipoproteins (HDL).
Laura Toma +5 more
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Frontiers in Physiology, 2013 Not all of the mysteries of life lie in our genetic code. Some can be found buried in our membranes. These shells of fat, sculpted in the central nervous system into the cellular (and subcellular) boundaries of neurons and glia, are themselves complex ...
Steffany A L Bennett +11 more
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Biomolecules, 2023 Clinical data implicate fluctuations of high levels of plasma glucose in cardiovascular diseases. Endothelial cells (EC) are the first cells of the vessel wall exposed to them.
Laura Toma +5 more
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The EMBO Journal, 2005 The cellular lipidome comprises over 1000 different lipids. Most lipids look similar having a polar head and hydrophobic tails. Still, cells recognize lipids with exquisite specificity. The functionality of lipids is determined by their local concentration, which varies between organelles, between the two leaflets of the lipid bilayer and even within ...
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Analytica Chimica Acta, 2019 The mainstream of lipidomics involves mass spectrometry-based, systematic, and large-scale studies of the structure, composition, and quantity of lipids in biological systems such as organs, cells, and body fluids. As increasingly more researchers in broad fields are beginning to pay attention to and actively learn about the lipidomic technology, some ...
Jianing Wang, Chunyan Wang, Xianlin Han
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Myocardial Lipidomics. Developments in myocardial nuclear lipidomics [PDF]
Frontiers in Bioscience, 2007 The development of electrospray ionization mass spectrometry has been critical for the analyses of lipidomes from subcellular organelles. The myocardial nuclear lipidome likely has a key role in the molecular regulation of gene expression. In fact, recent studies have suggested that specific phospholipid classes bind and regulate specific transcription
Carolyn J. Albert +4 more
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Regulation of microRNAs in high-fat diet induced hyperlipidemic hamsters
Scientific Reports, 2020 Dyslipidemia is a documented risk factor for cardiovascular diseases and other metabolic disorders. Therefore, the analysis of hyperlipidemia (HL)-related miRNAs is a potential approach for achieving new prognostic markers in lipid-metabolism related ...
Teodora Barbalata +7 more
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Plant Methods, 2018 Background Lipidomics plays an important role in understanding plant adaptation to different stresses and improving our knowledge of the genes underlying lipid metabolism.
Sunitha Shiva +5 more
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Advanced Science, 2023 AbstractLipid metabolism and signalling play pivotal functions in biology and disease development. Despite this, there is currently no optical technique available that can directly visualise the lipidome in tissues. In this study, we introduce opto-lipidomics, a new approach to optical molecular tissue imaging.
Magnus Jensen +13 more
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