Results 21 to 30 of about 57,903 (321)
Substrate-Specific Inhibition Constants for Phospholipase A2 Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics. [PDF]
, 2019 Assaying lipolytic enzymes is extremely challenging because they act on water-insoluble lipid substrates, which are normally components of micelles, vesicles, and cellular membranes.
Armando, Aaron +2 more
core +6 more sources
Toward a Standardized Strategy of Clinical Metabolomics for the Advancement of Precision Medicine [PDF]
, 2020 Despite the tremendous success, pitfalls have been observed in every step of a clinical metabolomics workflow, which impedes the internal validity of the study.
Kang, Yun Pyo +6 more
core +1 more source
Utility of mass spectrometry for the diagnosis of the unstable coronary plaque. [PDF]
, 2015 Mass spectrometry is a powerful technique that is used to identify unknown compounds, to quantify known materials, and to elucidate the structure and chemical properties of molecules.
Hassan, M, Jacob, SS, Yacoub, MH
core +1 more source
Biomolecules, 2021 Atherosclerosis is the main cause of cardiovascular diseases with high prevalence worldwide. A promising therapeutic strategy to reverse atherosclerotic process is to improve the athero-protective potential of high-density lipoproteins (HDL).
Laura Toma +5 more
doaj +1 more source
Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]
, 2018 The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela +5 more
core +1 more source
The EMBO Journal, 2005 The cellular lipidome comprises over 1000 different lipids. Most lipids look similar having a polar head and hydrophobic tails. Still, cells recognize lipids with exquisite specificity. The functionality of lipids is determined by their local concentration, which varies between organelles, between the two leaflets of the lipid bilayer and even within ...
openaire +3 more sources
Plant Methods, 2018 Background Lipidomics plays an important role in understanding plant adaptation to different stresses and improving our knowledge of the genes underlying lipid metabolism.
Sunitha Shiva +5 more
doaj +1 more source
Metabolites, 2023 There was an error in the original publication [...]
Hieu Sy Vu +17 more
doaj +1 more source
Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts
, 2020 A comprehensive characterization of the lipidome from limited starting material remains very challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid chromatography and trapped ion mobility spectrometry (TIMS).
Barsch, A. +8 more
core +1 more source
Neuronal human BACE1 knock-in induces systemic diabetes in mice [PDF]
, 2016 Acknowledgements The authors thank S. Tammireddy (Diabetes and Cardiovascular Science, University of the Highlands and Islands, Inverness, UK) for technical support with the lipidomics component. Funding We would like to thank R.
Dekeryte, Ruta +12 more
core +4 more sources