Results 21 to 30 of about 35,333 (282)

An efficient modified method for plant leaf lipid extraction results in improved recovery of phosphatidic acid

open access: yesPlant Methods, 2018
Background Lipidomics plays an important role in understanding plant adaptation to different stresses and improving our knowledge of the genes underlying lipid metabolism.
Sunitha Shiva   +5 more
doaj   +1 more source

Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release

open access: yesNature Communications, 2023
Microglial reactivity is a pathological hallmark in many neurodegenerative diseases. During stimulation, microglia undergo complex morphological changes, including loss of their characteristic ramified morphology, which is routinely used to detect and ...
Max Adrian   +9 more
doaj   +1 more source

Correction: Vu et al. Specific Changes in Arabidopsis thaliana Rosette Lipids during Freezing Can Be Associated with Freezing Tolerance. Metabolites 2022, 12, 385

open access: yesMetabolites, 2023
There was an error in the original publication [...]
Hieu Sy Vu   +17 more
doaj   +1 more source

Neuronal porosome lipidome [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2014
AbstractCup‐shaped lipoprotein structures called porosomes are the universal secretory portals at the cell plasma membrane, where secretory vesicles transiently dock and fuse to release intravesicular contents. In neurons, porosomes measure ~15 nm and are comprised of nearly 40 proteins, among them SNAREs, ion channels, the Gαo G‐protein and several ...
Lewis, Kenneth T   +3 more
openaire   +2 more sources

Mycobacterial Lipidomics

open access: yesMicrobiology Spectrum, 2014
ABSTRACTLipidomics is a distinct subspecialty of metabolomics concerned with hydrophobic molecules that organize into membranes. Most of the lipid classes present inMycobacterium tuberculosisare found only inActinobacteriaand show extreme structural diversity. This article highlights the conceptual basis and the practical challenges associated with the
Layre, Emilie   +3 more
openaire   +2 more sources

The impact of genetic stress by ATGL deficiency on the lipidome of lipid droplets from murine hepatocytes

open access: yesJournal of Lipid Research, 2013
We showed earlier that nutritional stress like starvation or high-fat diet resulted in phenotypic changes in the lipidomes of hepatocyte lipid droplets (LDs), representative for the pathophysiological status of the mouse model.
Chandramohan Chitraju   +9 more
doaj   +1 more source

Regulation of microRNAs in high-fat diet induced hyperlipidemic hamsters

open access: yesScientific Reports, 2020
Dyslipidemia is a documented risk factor for cardiovascular diseases and other metabolic disorders. Therefore, the analysis of hyperlipidemia (HL)-related miRNAs is a potential approach for achieving new prognostic markers in lipid-metabolism related ...
Teodora Barbalata   +7 more
doaj   +1 more source

Specific Changes in Arabidopsis thaliana Rosette Lipids during Freezing Can Be Associated with Freezing Tolerance

open access: yesMetabolites, 2022
While the roles of a few specific lipids in plant freezing tolerance are understood, the effect of many plant lipids remains to be determined. Acclimation of plants to non-freezing cold before exposure to freezing temperatures improves the outcome of ...
Hieu Sy Vu   +17 more
doaj   +1 more source

Recommendations for good practice in MS-based lipidomics

open access: yesJournal of Lipid Research, 2021
In the last 2 decades, lipidomics has become one of the fastest expanding scientific disciplines in biomedical research. With an increasing number of new research groups to the field, it is even more important to design guidelines for assuring high ...
Harald C. Köfeler   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy