Results 31 to 40 of about 35,333 (282)

Phenolic Compounds Exerting Lipid-Regulatory, Anti-Inflammatory and Epigenetic Effects as Complementary Treatments in Cardiovascular Diseases

Biomolecules, 2020
Atherosclerosis is the main process behind cardiovascular diseases (CVD), maladies which continue to be responsible for up to 70% of death worldwide. Despite the ongoing development of new and potent drugs, their incomplete efficacy, partial intolerance ...
Laura Toma, Gabriela Maria Sanda, Loredan Stefan Niculescu, Mariana Deleanu, Anca Volumnia Sima, Camelia Sorina Stancu   +5 more
doaj   +1 more source

A Critical Overview of HPLC-MS-Based Lipidomics in Determining Triacylglycerol and Phospholipid in Foods

Foods, 2023
With the current advancement in mass spectrometry (MS)-based lipidomics, the knowledge of lipidomes and their diverse roles has greatly increased, enabling a deeper understanding of the action of bioactive lipid molecules in plant- and animal-based foods.
JuDong Yeo, JaeYoon Kang, HyeonJin Kim, Chaeeun Moon   +3 more
doaj   +1 more source

Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress

Journal of Lipid Research, 2012
Liver steatosis can be induced by fasting or high-fat diet. We investigated by lipidomic analysis whether such metabolic states are reflected in the lipidome of hepatocyte lipid droplets (LDs) from mice fed normal chow diet (FED), fasted (FAS), or fed a ...
Chandramohan Chitraju, Martin Trötzmüller, Jürgen Hartler, Heimo Wolinski, Gerhard G. Thallinger, Achim Lass, Rudolf Zechner, Robert Zimmermann, Harald C. Köfeler, Friedrich Spener   +9 more
doaj   +1 more source

Clinical lipidomics: a new way to diagnose human diseases

Clinical and Translational Medicine, 2018
Lipidomics is a measurement of a large scale of lipid species to understand roles of their carbon atoms, dual bonds, or isomerism in the lipid molecule.
Jiapei Lv, Linlin Zhang, Furong Yan, Xiangdong Wang   +3 more
doaj   +1 more source

Advances in lipidomics [PDF]

Clinica Chimica Acta, 2020
The present article examines recently published literature on lipids, mainly focusing on research involving glycero-, glycerophospho- and sphingo-lipids. The primary aim is identification of distinct profiles in biologic lipidomic systems by ultra-high-performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS, tandem MS) with ...
Henri F. Avela, Heli Sirén
openaire   +2 more sources

Clinical lipidomics reveals high individuality and sex specificity of circulatory lipid signatures: a prospective healthy population study

Journal of Lipid Research
Lipid metabolism and circulatory lipid levels are tightly associated with the (cardio)metabolic health. Consequently, MS-based lipidomics has emerged as a powerful phenotyping tool in epidemiological, human population, and in clinical intervention ...
Jessica Medina, Nicolas Goss, Gonçalo dos Santos Correia, Rebecca Borreggine, Tony Teav, Zoltan Kutalik, Pedro Marques Vidal, Hector Gallart-Ayala, Julijana Ivanisevic   +8 more
doaj   +1 more source

Evaluating Software Tools for Lipid Identification from Ion Mobility Spectrometry–Mass Spectrometry Lipidomics Data

Molecules, 2023
The unambiguous identification of lipids is a critical component of lipidomics studies and greatly impacts the interpretation and significance of analyses as well as the ultimate biological understandings derived from measurements.
Dylan H. Ross, Jian Guo, Aivett Bilbao, Tao Huan, Richard D. Smith, Xueyun Zheng   +5 more
doaj   +1 more source

BioPAN: a web-based tool to explore mammalian lipidome metabolic pathways on LIPID MAPS [version 2; peer review: 3 approved]

F1000Research, 2021
Lipidomics increasingly describes the quantification using mass spectrometry of all lipids present in a biological sample.  As the power of lipidomics protocols increase, thousands of lipid molecular species from multiple categories can now be profiled ...
Caroline Gaud, Bebiana C. Sousa, An Nguyen, Maria Fedorova, Zhixu Ni, Valerie B. O’Donnell, Michael J.O. Wakelam, Simon Andrews, Andrea F. Lopez-Clavijo   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Rapid Movement of Palmitoleic Acid from Phosphatidylcholine to Phosphatidylinositol in Activated Human Monocytes

Biomolecules
This work describes a novel route for phospholipid fatty acid remodeling involving the monounsaturated fatty acid palmitoleic acid. When administered to human monocytes, palmitoleic acid rapidly incorporates into membrane phospholipids, notably into ...
Miguel A. Bermúdez, Alvaro Garrido, Laura Pereira, Teresa Garrido, María A. Balboa, Jesús Balsinde   +5 more
doaj   +1 more source