Results 31 to 40 of about 30,733 (194)

Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release

Nature Communications, 2023
Microglial reactivity is a pathological hallmark in many neurodegenerative diseases. During stimulation, microglia undergo complex morphological changes, including loss of their characteristic ramified morphology, which is routinely used to detect and ...
Max Adrian, Martin Weber, Ming-Chi Tsai, Caspar Glock, Olga I. Kahn, Lilian Phu, Tommy K. Cheung, William J. Meilandt, Christopher M. Rose, Casper C. Hoogenraad   +9 more
doaj   +1 more source

Correction: Vu et al. Specific Changes in Arabidopsis thaliana Rosette Lipids during Freezing Can Be Associated with Freezing Tolerance. Metabolites 2022, 12, 385

Metabolites, 2023
There was an error in the original publication [...]
Hieu Sy Vu, Sunitha Shiva, Thilani Samarakoon, Maoyin Li, Sujon Sarowar, Mary R. Roth, Pamela Tamura, Samuel Honey, Kaleb Lowe, Hollie Porras, Neema Prakash, Charles A. Roach, Morgan Stuke, Xuemin Wang, Jyoti Shah, Gary Gadbury, Haiyan Wang, Ruth Welti   +17 more
doaj   +1 more source

Mycobacterial Lipidomics

Microbiology Spectrum, 2014
ABSTRACTLipidomics is a distinct subspecialty of metabolomics concerned with hydrophobic molecules that organize into membranes. Most of the lipid classes present inMycobacterium tuberculosisare found only inActinobacteriaand show extreme structural diversity. This article highlights the conceptual basis and the practical challenges associated with the
Layre, Emilie, Al-Mubarak, Reem, Belisle, J.T., Moody, D. Branch   +3 more
openaire   +2 more sources

A Critical Overview of HPLC-MS-Based Lipidomics in Determining Triacylglycerol and Phospholipid in Foods

Foods, 2023
With the current advancement in mass spectrometry (MS)-based lipidomics, the knowledge of lipidomes and their diverse roles has greatly increased, enabling a deeper understanding of the action of bioactive lipid molecules in plant- and animal-based foods.
JuDong Yeo, JaeYoon Kang, HyeonJin Kim, Chaeeun Moon   +3 more
doaj   +1 more source

Clinical lipidomics: a new way to diagnose human diseases

Clinical and Translational Medicine, 2018
Lipidomics is a measurement of a large scale of lipid species to understand roles of their carbon atoms, dual bonds, or isomerism in the lipid molecule.
Jiapei Lv, Linlin Zhang, Furong Yan, Xiangdong Wang   +3 more
doaj   +1 more source

Lipidomics of familial longevity [PDF]

Aging Cell, 2013
SummaryMiddle‐aged offspring of nonagenarians, as compared to their spouses (controls), show a favorable lipid metabolism marked by larger LDL particle size in men and lower total triglyceride levels in women. To investigate which specific lipids associate with familial longevity, we explore the plasma lipidome by measuring 128 lipid species using ...
Gonzalez-Covarrubias, V., Beekman, M., Uh, H.W., Dane, A., Troost, J., Paliukhovich, I., Kloet, F.M. van der, Houwing-Duistermaat, J., Vreeken, R.J., Hankemeier, T., Slagboom, E.P.   +10 more
openaire   +3 more sources

Specific Changes in Arabidopsis thaliana Rosette Lipids during Freezing Can Be Associated with Freezing Tolerance

Metabolites, 2022
While the roles of a few specific lipids in plant freezing tolerance are understood, the effect of many plant lipids remains to be determined. Acclimation of plants to non-freezing cold before exposure to freezing temperatures improves the outcome of ...
Hieu Sy Vu, Sunitha Shiva, Thilani Samarakoon, Maoyin Li, Sujon Sarowar, Mary R. Roth, Pamela Tamura, Samuel Honey, Kaleb Lowe, Hollie Porras, Neema Prakash, Charles A. Roach, Morgan Stuke, Xuemin Wang, Jyoti Shah, Gary Gadbury, Haiyan Wang, Ruth Welti   +17 more
doaj   +1 more source

Lipidomics in Biomarker Research [PDF]

, 2021
AbstractLipids are natural substances found in all living organisms and involved in many biological functions. Imbalances in the lipid metabolism are linked to various diseases such as obesity, diabetes, or cardiovascular disease. Lipids comprise thousands of chemically distinct species making them a challenge to analyze because of their great ...
openaire   +3 more sources

Neuronal porosome lipidome [PDF]

Journal of Cellular and Molecular Medicine, 2014
AbstractCup‐shaped lipoprotein structures called porosomes are the universal secretory portals at the cell plasma membrane, where secretory vesicles transiently dock and fuse to release intravesicular contents. In neurons, porosomes measure ~15 nm and are comprised of nearly 40 proteins, among them SNAREs, ion channels, the Gαo G‐protein and several ...
Douglas J. Taatjes, Bhanu P. Jena, Krishna Rao Maddipati, Kenneth T. Lewis   +3 more
openaire   +3 more sources

Phenolic Compounds Exerting Lipid-Regulatory, Anti-Inflammatory and Epigenetic Effects as Complementary Treatments in Cardiovascular Diseases

Biomolecules, 2020
Atherosclerosis is the main process behind cardiovascular diseases (CVD), maladies which continue to be responsible for up to 70% of death worldwide. Despite the ongoing development of new and potent drugs, their incomplete efficacy, partial intolerance ...
Laura Toma, Gabriela Maria Sanda, Loredan Stefan Niculescu, Mariana Deleanu, Anca Volumnia Sima, Camelia Sorina Stancu   +5 more
doaj   +1 more source