Results 11 to 20 of about 8,324 (204)
Lipoarabinomannan in Active and Passive Protection Against Tuberculosis [PDF]
Frontiers in Immunology, 2019 Glycolipids of the cell wall of Mycobacterium tuberculosis (Mtb) are important immunomodulators in tuberculosis. In particular, lipoarabinomannan (LAM) has a profound effect on the innate immune response. LAM and its structural variants can be recognized
Margarida Correia-Neves +6 more
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Capillary zone electrophoresis of lipoarabinomannan by multi‐layered concentration [PDF]
Journal of Separation Science, 2022 AbstractThe present article describes a capillary zone electrophoresis method which relies on a multilayered water‐alkali solvent stacking with online ionization to enhance detection of mannose, arabinose, and their oligosaccharides, which are used as the migration profile standards but are also the distinctive structural components of ...
Eeva Marja Pitkänen +1 more
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PLoS Pathogens, 2023 The covalent modification of bacterial (lipo)polysaccharides with discrete substituents may impact their biosynthesis, export and/or biological activity.
Zuzana Palčeková +17 more
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Evaluation of lipoarabinomannan in the diagnosis of tuberculosis
The Egyptian Journal of Bronchology, 2016 Background The detection of lipoarabinomannan (LAM) antigens in body fluids has several potential advantages compared with the diagnostic methods used currently.
Ayman A. Youssef +4 more
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A Sensitive Urinary Lipoarabinomannan Test for Tuberculosis [PDF]
PLOS ONE, 2015 We have previously developed a diagnostic test for tuberculosis based on detection of mycobacterial lipoarabinomannan (LAM) in urine. The method depended on a laborious concentration step. We have now developed an easy to perform test based on a magnetic immunoassay platform, utilizing high avidity monoclonal antibodies for the detection of LAM in ...
Hamasur, Beston +4 more
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Collected Thoughts on Mycobacterial Lipoarabinomannan, a Cell Envelope Lipoglycan
Pathogens, 2023 The presence of lipoarabinomannan (LAM) in the Mycobacterium tuberculosis (Mtb) cell envelope was first reported close to 100 years ago. Since then, numerous studies have been dedicated to the isolation, purification, structural definition, and ...
Jordi B. Torrelles, Delphi Chatterjee
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Structural and functional features of Rhodococcus ruber lipoarabinomannan
Microbiology, 2003 The genusRhodococcusis part of the phylogenetic group nocardioform actinomycetes, which also includes the genusMycobacterium. Members of this phylogenetic group have a characteristic cell envelope structure, which is dominated by various complex lipids.
Gibson, Kevin +5 more
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REGULATION OF LIPOMANNAN AND LIPOARABINOMANNAN BIOSYNTHESIS IN MYCOBACTERIA [PDF]
, 2019 The integrity of the multilaminate cell envelope surrounding mycobacteria is critical for survival and pathogenesis. The prevalence of phosphatidylinositol mannosides in the cell envelope suggests an important role in the mycobacterial life cycle.
Rahlwes, Kathryn
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Identification of a lipoarabinomannan-like lipoglycan in the actinomycete Gordonia bronchialis
Archives of Microbiology, 2005 The cell envelopes of actinomycetes contain lipidated macroamphiphiles, of which the most extensively characterised are the lipoarabinomannans of mycobacteria and related bacteria. We have investigated the mycolic acid-containing actinomycete Gordonia bronchialis and identified the presence of a lipoarabinomannan-like lipoglycan.
Natalie J, Garton, Iain C, Sutcliffe
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Urine lipoarabinomannan testing for diagnosis of pulmonary tuberculosis in children: a prospective study [PDF]
The Lancet Global Health, 2014 Background: Urine tests for mycobacterial lipoarabinomannan might be useful for point-of-care diagnosis of tuberculosis in adults with advanced HIV infection, but have not been assessed in children.
Prof. Mark P Nicol, PhD +10 more
doaj +2 more sources