Results 21 to 30 of about 8,324 (204)

Urine Test Accuracy of Lipoarabinomannan in Diagnosing Pulmonary Tuberculosis in Adults: Meta-Analysis [PDF]

open access: yes, 2022
Background: Mycobacterium tuberculosis (Mt) requires non-sputum-based screening that can identify it with high sensitivity and specificity. Lipoarabinomannan (LAM) is a diagnosis of active tuberculosis (TB) in samples such as urine, both by complex ...
Ana, Kartika Febry   +4 more
core   +1 more source

Biosynthesis of Mycobacterial Lipoarabinomannan [PDF]

open access: yesJournal of Biological Chemistry, 1997
The mycobacterial lipoglycans, lipomannan (LM) and lipoarabinomannan (LAM), are potent immunomodulators in tuberculosis and leprosy. Little is known of their biosynthesis, other than being based on phosphatidylinositol (PI), and they probably originate in the phosphatidylinositol mannosides (PIMs; PIMans). A novel form of cell-free incubation involving
G S, Besra   +4 more
openaire   +2 more sources

Immunoassay with Novel Paired Antibodies for Detection of Lipoarabinomannan in the Pleural Fluid and Plasma of Patients with Tuberculous Pleurisy

open access: yesMicroorganisms, 2023
Tuberculous pleurisy (TP) is one of the most common forms of extrapulmonary tuberculosis, but its diagnosis is challenging. Lipoarabinomannan (LAM) antigen is a biomarker for Mycobacterium tuberculosis (Mtb) infection.
Zhuohong Yan   +9 more
doaj   +1 more source

Diagnostic value of the cerebrospinal fluid lipoarabinomannan assay for tuberculous meningitis: a systematic review and meta-analysis

open access: yesFrontiers in Public Health, 2023
ObjectiveThis systematic review aims to evaluate the diagnostic accuracy of cerebrospinal fluid (CSF) lipoarabinomannan (LAM) assays in detecting tuberculous meningitis (TBM).MethodsA systematic review search was conducted in PubMed and five other ...
Ya-Li Chen   +8 more
doaj   +1 more source

Biomarkers for tuberculosis: the case for lipoarabinomannan [PDF]

open access: yesERJ Open Research, 2019
Tuberculosis (TB) is considered the most onerous of infectious diseases according to recent reports from the World Health Organization. Available tests for TB diagnosis present severe limitations, and a reliable point-of-care (POC) diagnostic test does not exist.
Margarida Correia-Neves   +9 more
openaire   +4 more sources

Alere Determine-tuberculosis lipoarabinomannan positivity in disseminated non-tuberculous mycobacteria: An illustrative case series

open access: yesSouthern African Journal of HIV Medicine, 2022
Introduction: In outpatients, the World Health Organization recommends that the urine Alere Determine-tuberculosis lipoarabinomannan (AlereLAM) should be used to support the diagnosis of tuberculosis (TB) in people living with HIV (PLHIV) with CD4 counts
Riana Greyling   +2 more
doaj   +1 more source

Mannosylated Lipoarabinomannan Interacts with Phagocytes [PDF]

open access: yesEuropean Journal of Biochemistry, 1995
Infection by Mycobacterium tuberculosis first involves its adhesion to mononuclear host phagocytes. Various macrophage opsonic and non‐opsonic receptors are known to mediate this adhesion, with some specificity of mannosyl receptors for the more virulent strains. Mannosylated lipoarabinomannan, a major component of cell walls from M.
A, Venisse, J J, Fournié, G, Puzo
openaire   +2 more sources

Detection of lipoarabinomannan as a diagnostic test for tuberculosis [PDF]

open access: yesJournal of Clinical Microbiology, 1992
A coagglutination technique was established for the detection of lipoarabinomannan of Mycobacterium tuberculosis in human serum samples and evaluated for its utility in the diagnosis of tuberculosis at the Instituto Nacional de Enfermedades Respiratorias in Mexico City.
E, Sada   +3 more
openaire   +2 more sources

A systematic review of utility of urine lipoarabinomannan in detecting tuberculosis among HIV-positive tuberculosis suspects

open access: yesLung India, 2021
Sputum smear microscopy (SSM), though regarded as an inexpensive and popular method for detecting tuberculosis (TB), lacks adequate sensitivity, specifically in adult people living with HIV/AIDS (PLHIV).
Chakrapani Chatla   +4 more
doaj   +1 more source

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