Results 61 to 70 of about 8,324 (204)

Detection of lipoarabinomannan in urine for identification of active tuberculosis among HIV-positive adults in Ethiopian health centres.

, 2014
To assess the diagnostic performance of urine lipoarabinomannan (LAM) detection for TB screening in HIV-positive adults in ...
Skogmar, Sten, Björkman, Per, Balcha, Taye, Reepalu, Anton,, Skogmar, Sten,, Jemal, Zelalem H, Schön, Thomas,, Sturegard, Erik,, Tibesso, Gudeta,, Sturegård, Erik, Reepalu, Anton, Schön, Thomas, Tibesso, Gudeta, Winqvist, Niclas,, Lund University., Winqvist, Niclas, Balcha, Taye T.,, Jemal, Zelalem H.,, Bjorkman, Per,   +18 more
core   +1 more source

Feasibility of using Determine TB-LAM to diagnose tuberculosis in HIV-positive patients in programmatic conditions: a multisite study

Global Health Action, 2019
Background: Determine TB-LAM is a urine-based point-of-care assay for diagnosis of tuberculosis (TB). Objective: To assess the feasibility of using LAM to diagnose TB in adult HIV-positive patients in resource-limited settings.
Sekai Chenai Mathabire Rucker, Loide Cossa, Rebecca E. Harrison, James Mpunga, Sheila Lobo, Patrick Kisaka  Kimupelenge, Felix Mandar Kol’Ampwe, Isabel Amoros Quiles, Lucas Molfino, Elisabeth Szumilin, Oleksandr Telnov, Zibusiso Ndlovu, Helena Huerga   +12 more
doaj   +1 more source

Untersuchung von Anti‐Glykan‐Antikörpern und Erforschung ihres medizinischen Potenzials mithilfe synthetischer Glykane

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity

, 2017
The Mycobacterium tuberculosis –specific antigen lipoarabinomannan measured in the urine of HIV-negative, pulmonary TB-infected patients correlates with disease severity.
Lance Liotta, Jorge Coronel, Hannah Steinberg, Luisa Paris, Fatima Zaidi, Emanuel F. Petricoin, Michael Harpole, Daniela E. Kirwan, Alessandra Luchini, Roberto Nisini, Robert H. Gilman, Neal Saini, Ruben Magni, Robyn Araujo   +13 more
core   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Quantitative analysis of a urine-based assay for detection of lipoarabinomannan in patients with tuberculosis [PDF]

, 2010
Urinary lipoarabinomannan (LAM) detection is a promising approach for rapid diagnosis of active tuberculosis (TB). In microbiologically confirmed TB patients, quantitative LAM detection results increased progressively with bacillary burden and ...
Dorman, Susan E., Martin, Desmond J., Neil A. Martinson, Susan E. Dorman, Martinson, Neil A., Chaisson, Richard E., Ebrahim Variava, Maunank Shah, Shah, Maunank, Variava, Ebrahim, Desmond J. Martin, Richard E. Chaisson   +11 more
core   +1 more source

Lipoarabinomannan Decreases Galectin-9 Expression and Tumor Necrosis Factor Pathway in Macrophages Favoring Mycobacterium tuberculosis Intracellular Growth

Frontiers in Immunology, 2017
Lipoarabinomannan (LAM) is a lipid virulent factor secreted by Mycobacterium tuberculosis (Mtb). LAM can be found in the sputum and urine of patients with active tuberculosis.
Leslie Chávez-Galán, Lucero Ramon-Luing, Claudia Carranza, Irene Garcia, Isabel Sada-Ovalle   +4 more
doaj   +1 more source

Lipoarabinomannan Localization and Abundance during Growth of Mycobacterium smegmatis [PDF]

Journal of Bacteriology, 2011
ABSTRACTLipoarabinomannan (LAM) is a structurally heterogeneous amphipathic lipoglycan present inMycobacteriumspp. and other actinomycetes, which constitutes a major component of the cell wall and exhibits a wide spectrum of immunomodulatory effects. Analysis ofMycobacterium smegmatissubcellular fractions and spheroplasts showed that LAM and lipomannan
Rakesh K, Dhiman, Premkumar, Dinadayala, Gavin J, Ryan, Anne J, Lenaerts, Alan R, Schenkel, Dean C, Crick   +5 more
openaire   +2 more sources

SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening

Advanced Science, Volume 13, Issue 49, 3 September 2026.
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen, Jiaqi Yu, Jing Xu, Lingqi Chen, Ninghao Zhang, Wenrui Li, Runmin Zeng, Xiaomin Luo, Yiqun Chang, Jiayin Lai, Wenshi Huang, Xiaochen Liang, Ting Zhao, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Xueqin Huang, Haibo Zhou, Junxia Zheng   +20 more
wiley   +1 more source

Image_1_Anti-Lipoarabinomannan-Specific Salivary IgA as Prognostic Marker for Leprosy Reactions in Patients and Cellular Immunity in Contacts.tif

, 2018
Leprosy causes the most common peripheral neuropathy of infectious etiology, posing an important public health problem worldwide. Understanding the molecular and immunological mechanisms of nerve damage induced by M.
Mayara Ingrid de Sousa Lima (5320154), Luiz Ricardo Goulart (569752), Isabela Maria Bernardes Goulart (4621930), André Alan Nahas (5320157)   +3 more
core   +1 more source