Results 81 to 90 of about 39,706 (298)
Pediatric Investigation, EarlyView.This review discusses how early antiretroviral therapy initiation, long‐acting therapies, and prevention of mother‐to‐child transmission contribute to improved pediatric human immunodeficiency virus outcomes. Despite these advances, treatment complications and challenges in transitioning to adult care remain major barriers to lifelong management ...
Klaudia Nowak +6 more
wiley +1 more source
Berardinelli-Seip Syndrome [PDF]
, 2011 We have reported two cases of Berardinelli-syndrome in a family which is a rare autosomal recessive disorder of the adipose tissue, originally described by Berardinelli and Seip, has been reported in approximately 120 patients of various ethnic origins ...
Dal, Sameer I, Patel, Hitesh
core +1 more source
Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons
Small Science, EarlyView.This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong +4 more
wiley +1 more source
BMC PediatricsIntroduction Lipodystrophy can cause poor glycemic control in addition to cosmetic problems in children and adolescents with type 1 diabetes mellitus.
Tsehaye Alemseged +4 more
doaj +1 more source
Aging Cell, EarlyView.cTAGE5 regulates LBR trafficking between the ER and the nucleus membrane to maintain the integrity of both the ER and the nuclear envelope. cTAGE5 KO results in LBR retention in the ER, reduced stability, and subsequent disruption of nuclear envelope integrity. ABSTRACT cTAGE5/MEA6 plays a pivotal role in COPII complex assembly, ER‐to‐Golgi trafficking,
Yaqing Wang +9 more
wiley +1 more source
Partial Lipodystrophy and Dermatomyositis [PDF]
Archives of Dermatology, 1991 To the Editor. — Partial lipodystrophy (PL) is characterized by a slow and symmetrical loss of subcutaneous fatty tissue, mainly involving the upper half of the body. We report a case of PL associated with dermatomyositis. Report of a Case. — In 1978, an 11-year-old boy began to notice proximal weakness in his limbs together with facial erythema ...
Boixeda, P. (Pablo) +3 more
openaire +3 more sources
Comorbidities and Survival in Patients with Lipodystrophy: An International Chart Review Study.
Journal of Clinical Endocrinology and Metabolism, 2019 CONTEXT Limited natural history data are available in patients with non-HIV-related lipodystrophy syndromes who never received disease-specific therapies, making interpretation of benefits of novel therapies in lipodystrophy syndromes challenging ...
B. Akıncı +12 more
semanticscholar +1 more source
Insulin-like growth factors and related proteins in plasma and cerebrospinal fluids of HIV-positive individuals. [PDF]
, 2015 BackgroundClinically significant dysregulation of the insulin-like growth factor (IGF) family proteins occurs in HIV-infected individuals, but the details including whether the deficiencies in IGFs contribute to CNS dysfunction are unknown.MethodsWe ...
Choi, Namjong +4 more
core +2 more sources
Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women
Clinical Endocrinology, EarlyView.ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan +14 more
wiley +1 more source
Dyslipidemia and nutritional status in patients HIV positive with Syndrome Lipodystrophy.
Revista de Epidemiologia e Controle de Infecção, 2014 Backgound and Objectives: Lipodystrophy in HIV is adversely affect the antiretroviral therapy (HAART), characterized by redistribution of body fat, as well as metabolic changes related to lipid profile, risk factor associated with increased ...
Isameriliam Rosaulem Pereira da Silva +4 more
doaj +1 more source