Results 1 to 10 of about 75,579 (341)
DAXX drives de novo lipogenesis and contributes to tumorigenesis
Nature Communications, 2023 Cancer cells exhibit elevated lipid synthesis. In breast and other cancer types, genes involved in lipid production are highly upregulated, but the mechanisms that control their expression remain poorly understood.
Iqbal Mahmud +23 more
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Metabolites, 2021 Elucidation of the mechanism of lipogenesis and fat deposition is essential for controlling excessive fat deposition in chicken. Studies have shown that gut microbiota plays an important role in regulating host lipogenesis and lipid metabolism.
Tao Zhang +9 more
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Lipogenesis in human adipose tissue
Journal of Lipid Research, 1968 The pathways and some critical enzymes involved in lipogenesis in adipose tissue from 82 patients have been studied. Of the glucose-(14)C metabolized to lipid by isolated adipose cells, approximately 0.6% was recovered in fatty acids and the rest in glyceride-glycerol. Palmitate-1-(14)C was readily incorporated into neutral lipid.
D. J. Galton
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The role of the glucose-sensing transcription factor carbohydrate-responsive element-binding protein pathway in termite queen fertility [PDF]
Open Biology, 2016 Termites are among the few animals that themselves can digest the most abundant organic polymer, cellulose, into glucose. In mice and Drosophila, glucose can activate genes via the transcription factor carbohydrate-responsive element-binding protein ...
David Sillam-Dussès +5 more
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Animals, 2021 A ban on the use of antibiotic growth promoters (AGPs) has fueled and promoted scientific research towards the identification of reliable and effective alternatives.
Joshua J. Flees +4 more
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Serotonin Regulates Lipogenesis in Adipose Tissues through Serotonin Receptor 2A [PDF]
Endocrinology and Metabolism, 2020 Background Obesity is defined as excessive fat mass and is a major cause of many chronic diseases such as diabetes, cardiovascular disease, and cancer. Increasing energy expenditure and regulating adipose tissue metabolism are important targets for the ...
Ko Eun Shong +4 more
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Frontiers in Pharmacology, 2022 Melanoma is the most aggressive type of skin cancer with a high incidence and low survival rate. More than half of melanomas present the activating BRAF mutations, along which V600E mutant represents 70%–90%.
Lei Wang +15 more
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A newly discovered role of metabolic enzyme PCK1 as a protein kinase to promote cancer lipogenesis
Cancer Communications, 2020 Highly active lipogenesis is essential for rapid tumor growth. Sterol regulatory element‐binding protein (SREBP) is a key transcriptional factor for lipogenesis and activated by reduced sterol and oxysterol levels.
Hongfei Jiang +3 more
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Foods, 2020 Silkworm, Bombyx mori, contains high amounts of beneficial nutrients, including amino acids, proteins, essential minerals, and omega-3 fatty acids. We have previously reported a technique for producing steamed and freeze-dried mature silkworm larval ...
Da-Young Lee +6 more
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Molecules, 2019 Lipogenesis plays a critical role in the growth and metastasis of tumors, which is becoming an attractive target for anti-tumor drugs. RA-XII, one of the cyclopeptide glycosides isolated from Rubia yunnanensis, exerts anti-tumor effects on liver cancer ...
Di Guo +6 more
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