Results 31 to 40 of about 16,244 (260)

O tecido adiposo como órgão endócrino: da teoria à prática Adipose tissue as an endocrine organ: from theory to practice

open access: yesJornal de Pediatria, 2007
OBJETIVOS Mostrar os avanços na pesquisa sobre o papel fisiológico do tecido adiposo branco, ressaltando o seu papel endócrino em processos inflamatórios, no comportamento alimentar, na sensibilização à insulina e na modulação do processo de aterogênese.
Miriam Helena Fonseca-Alaniz   +3 more
doaj   +1 more source

Berberine Improves Glucose and Lipid Metabolism in HepG2 Cells Through AMPKα1 Activation

open access: yesFrontiers in Pharmacology, 2020
AimThis study is designed to investigate whether or not AMP-activated protein kinase α1 (AMPKα1) is required for natural product berberine (BBR) to improve glucose and lipid metabolism in HepG2 cells.MethodsAMPKα1 knocked-out (KO, AMPKα1-/-) cells were ...
Gang Ren   +6 more
doaj   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

open access: yesHepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso   +16 more
wiley   +1 more source

Dietary fat source affects metabolism of fatty acids in pigs as evaluated by altered expression of lipogenic genes in liver and adipose tissues

open access: yesAnimal, 2009
Little is known about pig gene expressions related to dietary fatty acids (FAs) and most work have been conducted in rodents. The aim of this study was to investigate how dietary fats regulate fat metabolism of pigs in different tissues.
P. Duran-Montgé   +3 more
doaj   +1 more source

The role of the glucose-sensing transcription factor carbohydrate-responsive element-binding protein pathway in termite queen fertility [PDF]

open access: yesOpen Biology, 2016
Termites are among the few animals that themselves can digest the most abundant organic polymer, cellulose, into glucose. In mice and Drosophila, glucose can activate genes via the transcription factor carbohydrate-responsive element-binding protein ...
David Sillam-Dussès   +5 more
doaj   +1 more source

Serotonin Regulates Lipogenesis in Adipose Tissues through Serotonin Receptor 2A [PDF]

open access: yesEndocrinology and Metabolism, 2020
Background Obesity is defined as excessive fat mass and is a major cause of many chronic diseases such as diabetes, cardiovascular disease, and cancer. Increasing energy expenditure and regulating adipose tissue metabolism are important targets for the ...
Ko Eun Shong   +4 more
doaj   +1 more source

α-lipoic acid reduces fatty acid esterification and lipogenesis in adipocytes from overweight/obese subjects

open access: yes, 2014
Objective: α-Lipoic acid (α-LA) is a natural occurring antioxidant with beneficial effects on obesity. The aim of this study was to investigate the putative effects of α-LA on triglyceride accumulation and lipogenesis in subcutaneous adipocytes from ...
Patricia Pérez-Matute   +23 more
core   +1 more source

Noninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study

open access: yesHepatology Communications, EarlyView., 2022
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk   +6 more
wiley   +1 more source

Resveratrol Anti-Obesity Effects: Rapid Inhibition of Adipocyte Glucose Utilization

open access: yesAntioxidants, 2019
Studies in animal models of diabetes and obesity have shown that resveratrol mitigates complications of metabolic diseases, beyond those resulting from oxidative stress.
Christian Carpéné   +7 more
doaj   +1 more source

Organismal Fructose Metabolism in Health and Non-Alcoholic Fatty Liver Disease

open access: yesBiology, 2020
NAFLD has alarmingly increased, yet FDA-approved drugs are still lacking. An excessive intake of fructose, especially in liquid form, is a dietary risk factor of NAFLD. While fructose metabolism has been studied for decades, it is still controversial how
Shea Skenderian   +2 more
doaj   +1 more source

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