Results 171 to 180 of about 77,919 (340)

Mass spectrometry‐based mitochondrial proteomics for cancer biomarker discovery

VIEW, EarlyView.
Figure.1 Schematic diagram of MS‐based mitochondrial proteomics for cancer biomarker discovery. The workflow highlights the integration of advanced technological platforms in mitochondrial proteomics and their application in cancer biomarker discovery.
Zheng Cao, ZiKun Song, Weijie Zhou, Xiaohui Liu, Yanling Liu, Peng R. Chen, Kun Qian   +6 more
wiley   +1 more source

Standardized Ethanol Extract of Cassia mimosoides var. nomame Makino Ameliorates Obesity via Regulation of Adipogenesis and Lipogenesis in 3T3-L1 Cells and High-Fat Diet-Induced Obese Mice [PDF]

, 2023
So-Won Heo, Kyung‐Sook Chung, Young-Seo Yoon, Soo‐Yeon Kim, Hye-Shin Ahn, Yu‐Kyong Shin, Sun-Hee Lee, Kyung‐Tae Lee   +7 more
openalex   +1 more source

Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche

Insect Science, EarlyView.
Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley   +1 more source

A randomized 3-way crossover study indicates that high-protein feeding induces de novo lipogenesis in healthy humans [PDF]

, 2019
Evelina Charidemou, Tom Ashmore, Xuefei Li, Ben D. McNally, James A. West, Sonia Liggi, Matthew Harvey, Elise Orford, Julian L. Griffin   +8 more
openalex   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

Genomic Insights into Abdominal and Intramuscular Fat Deposition in Chickens and Their Implications for Productivity Traits: A Systematic Review. [PDF]

Animals (Basel)
Kochetova O, Korytina G, Timasheva Y, Gilyazova I, Akhmetshin A, Abdeeva G, Karunas A, Khusnutdinova E, Gusev O.   +8 more
europepmc   +1 more source

Androgen induces 3′UTR shortening of de novo lipogenesis genes by alternative polyadenylation in prostate cancer cells [PDF]

Weijie Sun, Fei Liang, Hui Zhao, Yun-Mei Wang, Zhongyin Zhou, Hui Xu, Hang Liu, Dong Tang, Anlong Xu, Yonggui Fu, Zhiheng Li, Jun Ouyang, Newton O. Otecko, Benxia Hu, Tengfei Ma, Xin Li, Dong-Dong Wu, Hui Zhao, Ya‐Ping Zhang   +18 more
openalex   +1 more source

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.

Cell Metabolism, 2019
J. Lally, Sarani Ghoshal, D. DePeralta, O. Moaven, Lan Wei, Ricard Masia, Derek J. Erstad, N. Fujiwara, Vivian Leong, Vanessa P. Houde, Alexander E. Anagnostopoulos, Alice Wang, Lindsay A. Broadfield, R. Ford, R. Foster, J. Bates, H. Sun, Ting Wang, Henry Liu, A. Ray, A. Saha, J. Greenwood, Sathesh Bhat, G. Harriman, Wenyan Miao, J. Rocnik, W. Westlin, P. Muti, T. Tsakiridis, H. J. Harwood, R. Kapeller, Y. Hoshida, K. Tanabe, G. Steinberg, B. Fuchs   +34 more
semanticscholar   +1 more source

System level network data and models attack cancer drug resistance

British Journal of Pharmacology, EarlyView.
Drug resistance is responsible for >90% of cancer related deaths. Cancer drug resistance is a system level network phenomenon covering the entire cell. Small‐scale interactomes and signalling network models of drug resistance guide directed drug development.
Márk Kerestély, Dávid Keresztes, Levente Szarka, Borbála M. Kovács, Klára Schulc, Dániel V. Veres, Peter Csermely   +6 more
wiley   +1 more source

Targeting lipogenesis promotes the synergistic effect of the selective HDAC6 inhibitor ITF3756 with bortezomib in colon cancer cells. [PDF]

Front Pharmacol
Franzò M, Zichittella C, Di Liberto D, Pratelli G, Affranchi F, Notaro A, Giuliano M, Emanuele S.   +7 more
europepmc   +1 more source