The impact of de novo lipogenesis on predicting survival and clinical therapy: an exploration based on a multigene prognostic model in hepatocellular carcinoma. [PDF]
Zhou X +14 more
europepmc +1 more source
Epigenetic Mechanisms in Childhood Obesity
Abstract Epigenetic mechanisms, including DNA methylation, histone modification, and activity of noncoding RNAs (nc RNAs), affect the regulation of gene expression. These mechanisms are regulated by numerous environmental factors and are critical at specific windows of biological development, when organs and systems plasticity is increased.
Guadalupe León‐Reyes +3 more
wiley +1 more source
Regulation of adipogenesis by nucleotides. [PDF]
Pinette JA +3 more
europepmc +1 more source
Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso +5 more
wiley +1 more source
The designer cytokine IC7Fc attenuates atherosclerosis development by targeting hyperlipidemia in mice. [PDF]
In Het Panhuis W +29 more
europepmc +1 more source
Lipogenesis in the rabbit: influence of age and nutrition
Florence Gondret
openalex +1 more source
The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin +6 more
wiley +1 more source
Effects of Fructose on Features of Steatotic Liver Disease in HepG2 Cells. [PDF]
Howes MT, King J, Rosengren RJ.
europepmc +1 more source
This study evaluated the combined effects of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on bone repair around immediately placed implants in type 2 diabetic rats. Resveratrol improved glycemic control and body weight, while aPDT increased implant stability and bone mineralization.
Letícia Pitol‐Palin +8 more
wiley +1 more source
High intensity interval training attenuate insulin resistance in diabetic rats accompanied by improvements in liver metabolism and spexin signaling. [PDF]
Khoramipour K +7 more
europepmc +1 more source

