Results 241 to 250 of about 75,579 (341)

The impact of de novo lipogenesis on predicting survival and clinical therapy: an exploration based on a multigene prognostic model in hepatocellular carcinoma. [PDF]

open access: yesJ Transl Med
Zhou X   +14 more
europepmc   +1 more source

Epigenetic Mechanisms in Childhood Obesity

open access: yesAnnals of the New York Academy of Sciences, EarlyView.
Abstract Epigenetic mechanisms, including DNA methylation, histone modification, and activity of noncoding RNAs (nc RNAs), affect the regulation of gene expression. These mechanisms are regulated by numerous environmental factors and are critical at specific windows of biological development, when organs and systems plasticity is increased.
Guadalupe León‐Reyes   +3 more
wiley   +1 more source

Regulation of adipogenesis by nucleotides. [PDF]

open access: yesBiochem Soc Trans
Pinette JA   +3 more
europepmc   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso   +5 more
wiley   +1 more source

The designer cytokine IC7Fc attenuates atherosclerosis development by targeting hyperlipidemia in mice. [PDF]

open access: yesSci Adv
In Het Panhuis W   +29 more
europepmc   +1 more source

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin   +6 more
wiley   +1 more source

Role of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on immediate implant placement in type 2 diabetic rats

open access: yesPhotochemistry and Photobiology, EarlyView.
This study evaluated the combined effects of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on bone repair around immediately placed implants in type 2 diabetic rats. Resveratrol improved glycemic control and body weight, while aPDT increased implant stability and bone mineralization.
Letícia Pitol‐Palin   +8 more
wiley   +1 more source

High intensity interval training attenuate insulin resistance in diabetic rats accompanied by improvements in liver metabolism and spexin signaling. [PDF]

open access: yesSci Rep
Khoramipour K   +7 more
europepmc   +1 more source

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