Results 1 to 10 of about 46,883 (208)
PLoS Pathogens, 2016 To thrive in diverse environments, bacteria must shift their metabolic output in response to nutrient bioavailability. In many bacterial species, such changes in metabolic flux depend upon lipoic acid, a cofactor required for the activity of enzyme ...
Azul Zorzoli +2 more
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Role of lipoic acid (Thioctic acid) in improving vitality of different tissue culture cells [PDF]
Journal of Applied Veterinary Sciences, 2016 The present obtained experimental results proved that addition of lipoic acid (LA) with its sodium salt in ratio of 0.1ml mole (mM) in the growth media has improved their physiological activities of different cell lines including MDBK, VERO and BHK21 ...
Maha R. Abd El-Fadile, Hussine A.H.M.
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THE COMBINATION OF α-LIPOIC ACID INTAKE WITH ECCENTRIC EXERCISE MODULATES ERYTHROPOIETIN RELEASE
Biology of Sport, 2014 The generation of reactive nitrogen/oxygen species (RN/OS) represents an important mechanism in erythropoietin (EPO) expression and skeletal muscle adaptation to physical and metabolic stress.
B. Morawin +4 more
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Synergistic antihyperglycemic effect of alpha lipoic acid with antidiabetic agents in the normoglycemic and streptozotocin-induced type 2 diabetic rats [PDF]
Acta Poloniae Pharmaceutica, 2023 The current study's main goal was to assess the supplementation effect of alpha lipoic acid with antidiabetic medications (metformin and sitagliptin) on normal and streptozotocin-induced blood glucose levels in normal and streptozotocin-induced diabetic ...
Rawsan Ali Sabri +2 more
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Comparative Characteristics of Dosage Forms of α-Lipoic Acid [PDF]
E3S Web of Conferences, 2020 α-Lipoic acid is a fatty acid, which in its physiological effect is on a par with vitamins and minerals, is a vitamin-like substance (vitamin N). A review of clinical trials of the effectiveness of α-lipoic acid in evidence-based diseases is presented ...
Shkolnikova Marina +2 more
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R-enantiomer of α-lipoic acid. Opportunities and prospects for clinical use
Mìžnarodnij Endokrinologìčnij Žurnal, 2021 The paper presents an analysis of current literature data on the use of the R-enantiomer of α-lipoic acid as an antihypertensive treatment in patients with hypertension and metabolic syndrome.
N.A. Kravchun +2 more
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Frontiers in Bioengineering and Biotechnology, 2020 Lipoic acid is a valuable organosulfur compound used as an antioxidant for dietary supplementation, and potentially anti-diabetic and anti-cancer. Currently, lipoic acid is obtained mainly through chemical synthesis, which requires toxic reagents and ...
Binbin Chen +7 more
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Encapsulation of α-Lipoic Acid in Halloysite Nanotubes
Applied Sciences, 2023 A nanocomposite material based on halloysite and α-lipoic acid was studied. The kinetics of the degradation process of α-lipoic acid under the influence of ultraviolet radiation and thermal stress in its native state and in the composition of a ...
Andrii Melnyk +2 more
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Knockout studies reveal an important role of plasmodium lipoic acid protein ligase a1 for asexual blood stage parasite survival [PDF]
, 2009 Lipoic acid (LA) is a dithiol-containing cofactor that is essential for the function of a-keto acid dehydrogenase complexes. LA acts as a reversible acyl group acceptor and 'swinging arm' during acyl-coenzyme A formation.
A Witkowski +37 more
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Frontiers in Pharmacology, 2021 We evaluated the neuro-, immuno-, and male reproductive toxicity of zinc oxide nanoparticles (ZnO NPs) alone and in combination with lead acetate. We also studied the therapeutic role of α-lipoic acid postexposure.
Monika S. Deore +4 more
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