Lipolysis on Lipid Droplets: Mathematical Modelling and Numerical Discretisations [PDF]
Lipolysis is a life-essential metabolic process, which supplies fatty acids stored in lipid droplets to the body in order to match the demands of building new cells and providing cellular energy. In this paper, we present a first mathematical modelling approach for lipolysis, which takes into account that the involved enzymes act on the surface of ...
arxiv
Studies of Fat Lipolysis by Post-Heparin Human Plasma Lipoprotein Lipase and by Human Pancreatic Lipase [PDF]
Hyman Engelberg
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Food-grade micro-encapsulation systems that may induce satiety via delayed lipolysis: A review
The increasing prevalence of overweight and obesity requires new, effective prevention and treatment strategies. One approach to reduce energy intake is by developing novel foods with increased satiating properties, which may be accomplished by slowing ...
Meinou N. Corstens+5 more
semanticscholar +1 more source
Pioglitazone Enhances Cytosolic Lipolysis, β-oxidation and Autophagy to Ameliorate Hepatic Steatosis
Non-alcoholic fatty liver disease closely contributes to the development of obesity and insulin resistance. Even though pioglitazone has been reported to effectively lessen hepatic steatosis in human studies, its molecular mechanism remains unclear. This
P. Hsiao+5 more
semanticscholar +1 more source
Role of endogenous lipid droplets in lipolysis in rat adipocytes.
Sonication of rat fat cells caused an increase in lipolysis in the absence of lipolytic stimulants (basal lipolysis) and loss of epinephrine responsiveness.
H Okuda, C Morimoto, T Tsujita
doaj
In vivo mapping organellar metabolism by optical-boxcar enhanced fluorescence-detected mid-infrared photothermal microscopy [PDF]
Metabolism unfolds within specific organelles in eukaryotic cells. Lysosomes are highly metabolically active organelles, and their metabolic states dynamically influence signal transduction, cellular homeostasis, and organismal physiopathology. Despite the significance of lysosomal metabolism, a method for its in vivo measurement is currently lacking ...
arxiv
Obesity induces white adipose tissue (WAT) dysfunction characterized by unremitting inflammation and fibrosis, impaired adaptive thermogenesis and increased lipolysis.
Verónica García‐Alonso+9 more
semanticscholar +1 more source
Effects of sphingomyelin and cholesterol on lipoprotein lipase-mediated lipolysis in lipid emulsions
Lipoprotein lipase (LPL) hydrolyzes triacylglycerol (TG) of TG-rich lipoproteins. We investigated the effects of sphingomyelin (SM) and cholesterol (Chol) on the lipolysis of lipid emulsions by LPL using human apolipoprotein C-II (apoC-II) or plasma as ...
Itaru Arimoto+4 more
doaj
Fat storage and mobilization in adipose tissue play a central role in energy metabolism and are directly linked to the development of obesity. Upon starvation, fat is mobilized from adipose tissue by lipolysis, a process by which triglycerides are ...
Meiqin Huang+8 more
doaj
Hormonal regulation of lipolysis and phosphorylase activity in human fat cells [PDF]
Jay Moskowitz, John N. Fain
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