Results 71 to 80 of about 144,905 (388)
Nature Cell Biology, 2015 Chaperone-mediated autophagy (CMA) selectively degrades a subset of cytosolic proteins in lysosomes. A potent physiological activator of CMA is nutrient deprivation, a condition in which intracellular triglyceride stores or lipid droplets (LDs) also ...
Susmita Kaushik, A. Cuervo
semanticscholar +1 more source
Adipocyte lipolysis drives acute stress-induced insulin resistance
Scientific Reports, 2020 Stress hyperglycemia and insulin resistance are evolutionarily conserved metabolic adaptations to severe injury including major trauma, burns, or hemorrhagic shock (HS).
V. Raje +13 more
semanticscholar +1 more source
Journal of Dairy Science: Lipolysis is an ongoing issue for the French dairy industry that must be minimized. Milk lipolysis is defined as the hydrolysis of triglycerides, the major component of milk fat, resulting in the release of short-chain fatty acids responsible for ...
C. Hurtaud, L. Bernard, A. Rau, C. Cebo
doaj +1 more source
Shared genetic loci for body fat storage and adipocyte lipolysis in humans
Scientific Reports, 2022 Total body fat and central fat distribution are heritable traits and well-established predictors of adverse metabolic outcomes. Lipolysis is the process responsible for the hydrolysis of triacylglycerols stored in adipocytes.
Agné Kulyté +4 more
doaj +1 more source
Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis in the aged
Nature, 2017 Catecholamine-induced lipolysis, the first step in the generation of energy substrates by the hydrolysis of triglycerides, declines with age. The defect in the mobilization of free fatty acids in the elderly is accompanied by increased visceral adiposity,
Christina D. Camell +12 more
semanticscholar +1 more source
Mathematical modeling of laser lipolysis [PDF]
BioMedical Engineering OnLine, 2008 Liposuction continues to be one of the most popular procedures performed in cosmetic surgery. As the public's demand for body contouring continues, laser lipolysis has been proposed to improve results, minimize risk, optimize patient comfort, and reduce the recovery period.
Serge Mordon +3 more
openaire +4 more sources
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó +17 more
wiley +1 more source
Mljekarstvo, 2015 The aim of this study was to evaluate in detail the relationship between the basic milk components (fat and protein percentage) and the free fatty acids (FFA) content, as indicators of spontaneous and/or induced lipolysis. The additional aim of the study
Luděk Stádník +5 more
doaj +1 more source
Using blubber explants to investigate adipose function in grey seals:glycolytic, lipolytic and gene expression responses to glucose and hydrocortisone [PDF]
, 2017 Adipose tissue is fundamental to energy balance, which underpins fitness and survival. Knowledge of adipose regulation in animals that undergo rapid fat deposition and mobilisation aids understanding of their energetic responses to rapid environmental ...
Bennett, Kimberley A. +4 more
core +3 more sources
Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells
Advanced Functional Materials, EarlyView.Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri +4 more
wiley +1 more source