Results 111 to 120 of about 38,790 (251)

Biosurfactants: potential applications in medicine [PDF]

, 2006
The use and potential commercial application of biosurfactants in the medical field has increased during the past decade. Their antibacterial, antifungal and antiviral activities make them relevant molecules for applications in combating many diseases ...
Banat, Ibrahim M., Oliveira, Rosário, Rodrigues, L. R., Teixeira, J. A.   +3 more
core   +1 more source

Development of potent pan‐coronavirus fusion inhibitors with a new design strategy

MedComm
Development of potent and broad‐spectrum drugs against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) remains one of the top priorities, especially in the cases of the emergence of mutant viruses and inability of current vaccines to prevent
Yuanmei Zhu, Zhongcai Gao, Xiaoli Feng, Lin Cheng, Nian Liu, Chao Liu, Shaowei Han, Qiaojiang Yang, Qingcui Zou, Huihui Chong, Zheng Zhang, Minghua Li, Gengshen Song, Yuxian He   +13 more
doaj   +1 more source

Characterization of Antifungal Lipopeptide Biosurfactants Produced by Marine Bacterium Bacillus sp. CS30

Marine Drugs, 2019
This study was initiated to screen for marine bacterial agents to biocontrol Magnaporthe grisea, a serious fungal pathogen of cereal crops. A bacterial strain, isolated from the cold seep in deep sea, exhibited strong growth inhibition against M. grisea,
Shimei Wu, Ge Liu, Shengnan Zhou, Zhenxia Sha, Chaomin Sun   +4 more
doaj   +1 more source

Suppression of Sclerotinia sclerotiorum by the Induction of Systemic Resistance and Regulation of Antioxidant Pathways in Tomato Using Fengycin Produced by Bacillus amyloliquefaciens FZB42

Biomolecules, 2019
Lipopeptides from Bacillus species exhibit promising biological control activity against plant pathogens. This study aimed to explore the potential of purified fengycin to induce systemic resistance in tomato against Sclerotinia sclerotiorum.
Ayaz Farzand, Anam Moosa, Muhammad Zubair, Abdur Rashid Khan, Venance Colman Massawe, Hafiz Abdul Samad Tahir, Taha Majid Mahmood Sheikh, Muhammad Ayaz, Xuewen Gao   +8 more
doaj   +1 more source

IMPACT OF ENDOPHYTIC LIPOPEPTIDES USE AGAINST SOME PLANT PATHOGENIC MICROORGANISMS [PDF]

, 2020

openalex   +1 more source

Prospection for potential new non-ribosomal peptide gene clusters in Bacillus genus isolated from fermented foods and soil through genome mining

Frontiers in Microbiology
Experimental studies, though often very costly, lead to the discovery of known antimicrobial products. Yet, pathogenic microorganisms are proving increasingly resistant to pre-existing antimicrobial molecules, and this is a cause for worldwide concern ...
Blaise Waongo, Libère Ndayishimiye, François Tapsoba, Wend-Soo Abel Zongo, Jinquan Li, Aly Savadogo   +5 more
doaj   +1 more source

Seven New and Two Known Lipopeptides as well as Five Known Polyketides: The Activated Production of Silent Metabolites in a Marine-Derived Fungus by Chemical Mutagenesis Strategy Using Diethyl Sulphate

Marine Drugs, 2014
AD-2-1 is an antitumor fungal mutant obtained by diethyl sulfate mutagenesis of a marine-derived Penicillium purpurogenum G59. The G59 strain originally did not produce any metabolites with antitumor activities in MTT assays using K562 cells.
Chang-Jing Wu, Chang-Wei Li, Cheng-Bin Cui   +2 more
doaj   +1 more source

Antagonistic mechanism of Bacillus velezensis HX0039 as a biocontrol agent against Trichoderma virens-induced “Sanghuang” green mold

Applied and Environmental Microbiology
Green mold disease caused by Trichoderma spp. is one of the serious challenges in the production of “Sanghuang” mushroom (Sanghuangporus vaninii).
Ying Zhang, Wenheng Gao, Hui Zhang, Tao Sun, Huixiang Yang, Yan Liu, Xiaoyang Han, Dengke Yin, Weifang Xu   +8 more
doaj   +1 more source

Enhancing the solubility of SARS-CoV-2 inhibitors to increase future prospects for clinical development

Journal of Virology
SARS-CoV-2 poses an ongoing threat to human health as variants continue to emerge. Several effective vaccines are available, but a diminishing number of Americans receive the updated vaccines (only 22% received the 2023 update).
Ariel J. Kuhn, Victor K. Outlaw, Tara C. Marcink, Zhen Yu, Megan C. Mears, Maria N. Cajimat, Dale F. Kreitler, Payton R. Cleven, Jee Ching Mook, Dennis A. Bente, Matteo Porotto, Samuel H. Gellman, Anne Moscona   +12 more
doaj   +1 more source

Supramolecular Complexes of Ultrashort Cationic Lipopeptides with Cyclodextrins: Improved Selectivity and Therapeutic Potential

Aggregate
In the last decade, the rise of antibiotic resistance has heightened interest in antimicrobial peptides and lipopeptides as promising alternatives to conventional antibiotics because of their lower propensity to develop resistance.
Chiara Bellini, Unai Atxabal, Szilvia Bősze, Orsolya Dobay, Andrea Horváth, Imola Cs. Szigyártó, Tamás Beke‐Somfai, Jesús Jiménez‐Barbero, István Puskás, Kata Horváti   +9 more
doaj   +1 more source