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A gelatinized lipopeptide diet effectively modulates immune response, disease resistance and gut microbiome in Penaeus vannamei challenged with Vibrio parahaemolyticus.

Fish and Shellfish Immunology, 2021
Penaeus vannamei is one of the most economically vital shrimp globally, but infectious diseases have hampered its proper production and supply. As antibiotics pose a huge threat to the environment and humankind, it is essential to seek an alternative ...
R. Prathiviraj   +6 more
semanticscholar   +1 more source

Relationship between lipopeptide biosurfactant and primary metabolite production by Bacillus strains in solid-state and submerged fermentation.

Bioresource Technology, 2021
The relationship between lipopeptide and primary metabolite production by Bacillus spp. in solid-state fermentation (SSF) and submerged fermentation (SmF) was evaluated.
Luisa Marcela Valdés-Velasco   +5 more
semanticscholar   +1 more source

Revealing the effect of lipopeptide on improving the probiotics characteristics: Flavor and texture enhancer in the formulated yogurt.

Food Chemistry, 2021
Probiotics are beneficial viable microorganisms that protects from pathogens, enhance immunity and health. In this study, a biosurfactant from marine sponge associated bacteria MS48 was used to effectively enhance the survival of starter cultures and ...
A. Ravindran, G. Kiran, J. Selvin
semanticscholar   +1 more source

Self-Adjuvanting Lipopeptide Vaccines

Current Medicinal Chemistry, 2008
Despite the important role of adjuvants for vaccine development, relatively few adjuvants have been successfully incorporated into vaccines intended for human administration. This is in part due to the high toxicity associated with many experimental adjuvants. This lack of choice effectively hinders the ability to produce vaccines against many diseases,
Moyle, P.M., Toth, I.
openaire   +3 more sources

Lipopeptide Pepducins as Therapeutic Agents

2021
Pepducins are lipidated peptides that target the intracellular loops of G protein-coupled receptors (GPCRs) in order to modulate transmembrane signaling to internally located effectors. With a wide array of potential activities ranging from partial, biased, or full agonism to antagonism, pepducins represent a versatile class of compounds that can be ...
Emily, Michael   +2 more
openaire   +2 more sources

Lipopeptide adjuvants in combination treatment

International Immunopharmacology, 2003
Synthetic lipopeptides derived from the N-terminus of bacterial lipoprotein constitute potent immunoadjuvants for parenteral and mucosal immunization. When combined with tetanus toxoid (TT) or gliadin as antigens, the lipopeptide N-palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-(R)-cysteinyl-seryl-(lysyl)(3)-lysine (P(3)CSK(4)) markedly enhanced the ...
Bessler, Wolfgang G.   +3 more
openaire   +3 more sources

Lipopeptide preparation and analysis

2000
Lipophilic peptides and proteins present specific problems during preparation and analysis which require the use of modified methodology. This chapter discusses some of the methods that have been employed in the isolation and structural studies of the pulmonary surfactant-associated proteins B and C (SP-B and SP-C), other proteins with lipid-like ...
J, Johansson   +4 more
openaire   +2 more sources

Biocompatible Lipopeptide-Based Antibacterial Hydrogel

Biomacromolecules, 2019
A biocompatible hydrogel containing a hexapeptide as a key unit has been designed and fabricated. Our design construct comprises a β-sheet-rich short hexapeptide in the center with a hydrophobic long chain and hydrophilic triple lysine unit attached at the N- and C-terminals, respectively.
Anindyasundar Adak   +3 more
openaire   +2 more sources

Lipopeptide-based oral vaccine against hookworm infection.

Journal of Infectious Diseases, 2020
The human hookworm, Necator americanus, is a parasite that infects almost half a billion people worldwide. While treatment is available, vaccination is favorable to combat the spread of this parasite due to its wide distribution and continuous ...
Stacey Bartlett   +8 more
semanticscholar   +1 more source

Biosynthesis of isonitrile lipopeptides

Current Opinion in Chemical Biology
Isonitrile lipopeptides discovered from Actinobacteria have attracted wide attention due to their fascinating biosynthetic pathways and relevance to the virulence of many human pathogens including Mycobacterium tuberculosis. Specifically, the identification of the new class of isonitrile-forming enzymes that belong to non-heme iron (II) and α ...
Kaimin Jia   +3 more
openaire   +2 more sources

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