Results 51 to 60 of about 27,539 (254)

Solubilization and stabilization of isolated photosystem I complex with lipopeptide detergents. [PDF]

PLoS ONE, 2013
It is difficult to maintain a target membrane protein in a soluble and functional form in aqueous solution without biological membranes. Use of surfactants can improve solubility, but it remains challenging to identify adequate surfactants that can ...
Xiaoqiang Wang, Guihong Huang, Daoyong Yu, Baosheng Ge, Jiqian Wang, Fengxi Xu, Fang Huang, Hai Xu, Jian R Lu   +8 more
doaj   +1 more source

Understanding the Role of Self-Assembly and Interaction with Biological Membranes of Short Cationic Lipopeptides in the Effective Design of New Antibiotics

Antibiotics, 2022
This study investigates short cationic antimicrobial lipopeptides composed of 2–4 amino acid residues and C12-C18 fatty acids attached to the N-terminal part of the peptides. The findings were discussed in the context of the relationship among biological
Oktawian Stachurski, Damian Neubauer, Aleksandra Walewska, Emilia Iłowska, Marta Bauer, Sylwia Bartoszewska, Karol Sikora, Aleksandra Hać, Dariusz Wyrzykowski, Adam Prahl, Wojciech Kamysz, Emilia Sikorska   +11 more
doaj   +1 more source

Self-assembly of three bacterially-derived bioactive lipopeptides [PDF]

, 2013
The self-assembly in aqueous solution of three lipopeptides obtained from Bacillus subtilis has been investigated. The lipopeptides surfactin, plipastatin and mycosubtilin contain distinct cyclic peptide headgroups as well as differences in alkyl chain ...
Ashkan Dehsorkhi, Banat, Barth, Bonmatin, Bush, Béchet, Castelletto, Castelletto, Coutte, Cui, François Coutte, Gabrielle Chataigné, Grau, Hamley, Harnois, Ian W. Hamley, Isa, Ishigami, Jani Seitsonen, Janne Ruokolainen, Jauregi, Konarev, Krimm, Matson, Matson, Ongena, Ongena, Paramonov, Paula Jauregi, Pease, Philippe Jacques, Raaijmakers, Shen, Singh, Versluis, Webber, Woody, Zhao   +37 more
core   +2 more sources

Molecular characterization and antifungal activity of lipopeptides produced from Bacillus subtilis against plant fungal pathogen Alternaria alternata

BMC Microbiology, 2023
Over 380 host plant species have been known to develop leaf spots as a result of the fungus Alternaria alternata. It is an aspiring pathogen that affects a variety of hosts and causes rots, blights, and leaf spots on different plant sections.
B. N. Harish, S. N. Nagesha, B. N. Ramesh, S. Shyamalamma, M. S. Nagaraj, H. C. Girish, C. Pradeep, K. S. Shiva Kumar, K. S. Tharun Kumar, S. N. Pavan, V. Kavan Kumar   +10 more
doaj   +1 more source

Endophytic Bacillus altitudinis Q7 from Ginkgo biloba inhibits the growth of Alternaria alternata in vitro and its inhibition mode of action

Biotechnology & Biotechnological Equipment, 2021
The study was focussed on the inhibitory mechanism associated with the ability of an endophytic bacterium - Bacillus altitudinis Q7, obtained from Ginkgo biloba, to inhibit the growth of Alternaria alternata in vitro.
Mingqi Sun, Shuhong Ye, Zhichao Xu, Lu Wan, Yuguang Zhao   +4 more
doaj   +1 more source

Effects of Bacillus lipopeptides on the survival and behavior of the rosy apple aphid Dysaphis plantaginea

Ecotoxicology and Environmental Safety, 2021
Within the framework of biocontrol development, several natural lipopeptides produced by Bacillus subtilis show well-documented anti-microbial properties, especially in orchards.
Thomas Denoirjean, Géraldine Doury, Pedro Poli, François Coutte, Arnaud Ameline   +4 more
doaj   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Unraveling the senses of Phytophthora; leads to novel control strategies? [PDF]

, 2009
Oomycetes cause devastating diseases on plants and animals. They cause major yield losses in many crop plants and their control heavily depends on agrochemicals. This is certainly true for the potato late blight pathogen Phytophthora infestans.
Govers, F., Meijer, H.J.G., Raaijmakers, J.M., Tran, H., Wagemakers, L.   +4 more
core   +2 more sources

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source