Results 81 to 90 of about 27,539 (254)
Treatment of staphylococcal infections with cyclic lipopeptides [PDF]
Daptomycin is the first of a new class of antibiotics, the cyclic lipopeptides, for which a novel mechanism of action is hypothesised. Owing to its mode of action, daptomycin is rapidly bactericidal without being bacteriolytic, is active against static- and growing-phase bacteria, and has a low resistance rate in vitro.
openaire +3 more sources
Oomycete Phytophthora infestans [(Mont.) de Bary] is the cause of potato late blight, a plant disease which poses a serious threat to our global food security and is responsible for huge economic losses worldwide.
Youyou Wang +5 more
doaj +1 more source
The osmoadapted B. amyloliquefaciens VFS2 showed strong antifungal activities against Vicia faba‐pathogenic fungi and produced significant amounts of cLPs isoforms, indole‐3‐acetic acid, and siderophores under osmotic stress. These properties were associated with a Vicia faba Fusarium‐wilt disease biocontrol under saline and water‐deficient conditions.
Imen Haddoudi +5 more
wiley +1 more source
Nonribosomal peptides, key biocontrol components for Pseudomonas fluorescens In5, isolated from a Greenlandic suppressive soil. [PDF]
UnlabelledPotatoes are cultivated in southwest Greenland without the use of pesticides and with limited crop rotation. Despite the fact that plant-pathogenic fungi are present, no severe-disease outbreaks have yet been observed.
Dorrestein, Pieter C +6 more
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Daptomycin: A cyclic lipopeptide antimicrobial agent
The aims of this article were: to summarize the pharmacology, pharmacokinetics, and efficacy of daptomycin; to explore its safety profile; and to discuss its current and potential roles as an antimicrobial therapy.A literature search was conducted using the MEDLINE (1966-August 2004) and International Pharmaceutical Abstracts (1970-August 2004 ...
LilyAnn Jeu, Horatio B. Fung
openaire +3 more sources
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
Novel mutations in the toll like receptor genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection [PDF]
Toll like receptors play a central role in the recognition of pathogen associated molecular patterns (PAMPs). Mutations in TLR1, TLR2 and TLR4 genes may change the PAMP reorganization ability which causes altered responsiveness to the bacterial pathogens.
Ivan Mikula Jr. +6 more
core +1 more source
Background There is an urgent need to discover biocontrol agents to control bacterial wilt. This study reports on a new lipopeptide-producing biocontrol strain FJAT-46737 and explores its lipopeptidic compounds, and this study investigates the ...
Meichun Chen +7 more
doaj +1 more source
Scalable downstream method for the cyclic lipopetide jagaricin
Cyclic lipopeptides are substances with a high potential to act as antimicrobial agents. Jagaricin, produced by Janthinobacterium agaricidamnosum DSM 9628 and discovered in 2012, is a new member of this class with promising antifungal properties. However,
Jakob Stein +7 more
doaj +1 more source
This study investigates mutual interaction of skin microbes and surface lipids in AD using the advanced method of shotgun lipidomics with ultra‐broad coverage of lipids and 16S amplicon sequencing of tape strips taken from lesional and non‐lesional AD and healthy controls.
Madhumita Bhattacharyya +14 more
wiley +1 more source

