Results 51 to 60 of about 988,006 (285)

The analysis of lipophilic marine toxins : development of an alternative method [PDF]

, 2010
Lipophilic marine toxins are produced by certain algae species and can accumulate in filter feeding shellfish such as mussels, scallops and oysters. Consumption of contaminated shellfish can lead to severe intoxications such as diarrhea, abdominal cramps
Gerssen, A.
core  

Structural Basis of Guest-Host Interaction in the Gastrointestinal Delivery of Lipophilic Bioactive Compounds using Protein-based Vehicles

, 2023
Bioactive compounds, such as curcumin, lutein, coenzyme Q10, β-carotene, cholecalciferol, astaxanthin, and β-sitosterol, have antioxidant and anti-inflammatory properties that promote health, but their low solubility, fast metabolism, and degradation ...
Okagu, Ogadimma Desmond
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Rare Prenyllipids in Wild St. John’s Wort During Three Harvest Seasons

Molecules
St. John’s wort (Hypericum perforatum) is a medicinal plant known for its bioactive compounds, including tocopherols and tocotrienols, which possess antioxidant and anti-inflammatory properties.
Paweł Górnaś, Aleksander Siger
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Cryptotanshinone attenuates LPS-induced acute lung injury by regulating metabolic reprogramming of macrophage

Frontiers in Medicine, 2023
BackgroundAcute lung injury (ALI) is a life-threatening inflammatory disease without effective therapeutic regimen. Macrophage polarization plays a key role in the initiation and resolution of pulmonary inflammation.
Zesen Ye, Panxia Wang, Guodong Feng, Quan Wang, Cui Liu, Jing Lu, Jianwen Chen, Peiqing Liu   +7 more
doaj   +1 more source

Structural Characterisation of Bioactive Glasses [PDF]

, 2007
Melt-quenched glasses containing SiO2, CaO, Na2O and P2O5, and sol-gel derived glasses containing SiO2 and CaO are known to have bioactive properties. Foaming of binary sol-gel derived bioactive glasses containing SiO2 and CaO can be used to produce ...
Fitzgerald, Victoria
core  

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Pharmacokinetics-Driven Evaluation of the Antioxidant Activity of Curcuminoids and Their Major Reduced Metabolites—A Medicinal Chemistry Approach

Molecules, 2021
Curcuminoids are the main bioactive components of the well-known Asian spice and traditional medicine turmeric. Curcuminoids have poor chemical stability and bioavailability; in vivo they are rapidly metabolized to a set of bioreduced derivatives and/or ...
Gábor Girst, Sándor B. Ötvös, Ferenc Fülöp, György T. Balogh, Attila Hunyadi   +4 more
doaj   +1 more source

Characterizing the hierarchical structures of bioactive sol-gel silicate glass and hybrid scaffolds for bone regeneration [PDF]

, 2012
Bone is the second most widely transplanted tissue after blood. Synthetic alternatives are needed that can reduce the need for transplants and regenerate bone by acting as active temporary templates for bone growth.
Lee, P. D., Jones, Julian R., Jones, J. R., J. V. Hanna, Newport, Robert J., Hanna, J. V., Smith, M. E., Smith, Mark E., Smith, M.E., Martin, R.A., Yue, S., Hanna, John V., R. J. Newport, Martin, R. A., Lee, P.D., Jones, J.R., M. E. Smith, J. R. Jones, Newport, R. J., Martin, Richard A., R. A. Martin, P. D. Lee, Hanna, J.V., S. Yue   +23 more
core   +1 more source