Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu +9 more
wiley +1 more source
Development of a CHD risk prediction model using novel lipid markers based on lipidomics and VAP technology. [PDF]
Chen X +9 more
europepmc +1 more source
The effect of anti‐seizure medications on exposure to statins: A systematic review and meta‐analysis
Abstract Objectives Antiseizure medications (ASMs) can reduce the efficacy of statin treatment, partly due to reduction in statin concentrations. In this systematic review and network meta‐analysis (NMA), we compared the effects of ASMs and the prototypical enzyme inducer rifampin on statin exposure.
Sharon Valiyev Huino +5 more
wiley +1 more source
Atherogenic Index of Plasma in Relation to Angiographic Coronary Artery Disease Severity, Plasma Fatty Acid Composition, and Estimated Desaturase Activity: A Cross-Sectional Study. [PDF]
Batirel S +5 more
europepmc +1 more source
Abstract Objective Using a Dutch insurance claims registry, we examine whether people with epilepsy have an increased risk of major ischemic cardiovascular events or death compared to people without epilepsy. We also assess whether this risk differs between users of enzyme‐modulating and non‐enzyme‐modulating antiseizure medications (ASMs).
Paola Vassallo +4 more
wiley +1 more source
Abstract Background Treatment with the sodium‐glucose co‐transporter 2 (SGLT2) inhibitor canagliflozin in insulin dysregulated (ID) horses has shown promising results in randomised clinical trials. Larger field studies are needed to further evaluate treatment responses and potential adverse effects under real‐world conditions.
Moa Hällbom +3 more
wiley +1 more source
Hepatocyte-Specific <i>Nrf2</i> Deficiency Alters Cholesterol Metabolism, Leading to Mitigated Atherosclerosis in <i>ApoE</i>-Knockout Mice. [PDF]
Jiao J +21 more
europepmc +1 more source
Vaginal host–microbe signatures linked to placental outcomes in mares
Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule +7 more
wiley +1 more source
Lipid Metabolic Reprogramming in Periodontitis-Associated Alveolar Bone Remodeling: Mechanisms, Signaling Pathways, and Therapeutic Implications. [PDF]
Wang J +8 more
europepmc +1 more source

