Results 121 to 130 of about 93,526 (325)

Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Cognitive Decline by Restoring Senescent Microglial Function via NF‐κB‐SREBP1 Pathway Inhibition

open access: yesAging Cell, EarlyView.
Human umbilical cord‐derived mesenchymal stem cells (hUC‐MSCs) ameliorate age‐related cognitive decline by targeting senescent microglia. They attenuate microglial senescence, reduce LD accumulation, and inhibit the NF‐κB‐SREBP1 signaling pathway, ultimately mitigating neuroinflammation and neuronal damage.
Aihong Liang   +13 more
wiley   +1 more source

Glucagon and Plasma Lipoprotein Lipase

open access: yesExperimental Biology and Medicine, 1974
SummarySubcutaneous administration of 1.0 mg glucagon to 15 fasted normal people caused significant increase of plasma lipoprotein lipase-like activity in 1 hr. The activity is termed lipase-like since coconut oil emulsion rather than isolated chylomicrons was used as substrate.
Lucille Corbo, Raymond Caren
openaire   +3 more sources

Assessing the effect of statins in lowering the risk of stroke and preventing cerebral ischemia in patients with hypercholesterolemia [PDF]

open access: yes, 2017
Numerous analyses have explored the role of statins in reducing stroke incidence, reducing cerebral ischemia in hypercholesterolemic patients, and preventing ischemic stroke.
AlSulaiman, Wafa
core  

Integrating Dialysis in Ex Situ Machine Perfusion: A Systematic Review and Meta‐Analysis of Outcomes

open access: yesArtificial Organs, EarlyView.
Dialysis‐enhanced EVMP effectively maintains biochemical homeostasis, potentially mitigating metabolic stress and extending perfusion duration. Functional outcomes varied depending on the organ type, with the most pronounced benefits observed in cardiac perfusion.
Yomna E. Dean   +12 more
wiley   +1 more source

Mechanism of salt-mediated inhibition of lipoprotein lipase

open access: yesJournal of Lipid Research, 1976
The activity of lipoprotein lipase isolated from rat postheparin plasma has been determined with synthetic lipids, in the presence and absence of apoprotein of the natural substrate very low density lipoprotein, as a function of medium ion-pair ...
C J Fielding, P E Fielding
doaj   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

The lipoprotein lipase of mammary gland and the correlation of its activity to lactation

open access: yesJournal of Lipid Research, 1963
The concentration of lipoprotein lipase of guinea pig mammary gland increases markedly just prior to parturition, reaching a maximal level within 2 hr post-partum.
O.W. McBride, Edward D. Korn
doaj   +1 more source

Making Advanced Therapies Affordable and Accessible: Two Strategic Approaches

open access: yesDeveloping World Bioethics, EarlyView.
ABSTRACT This article explores two complementary strategies for addressing the affordability and access challenges facing advanced therapies. As high development costs and limited market access have led to the withdrawal of several therapies, the article examines how these barriers create ‘valleys of death’ that prevent innovation from reaching ...
Ubaka Ogbogu, Lauren Albrecht
wiley   +1 more source

The Effect of Melinjo Peel Extract in Activity of Lipoprotein Lipase Enzym of The Rats Fed a Hypercholesterolemia Diet

open access: yesJurnal Ilmiah Kedokteran Wijaya Kusuma, 2018
The intake of saturated fat and cholesterol that comes from food digested in the intestine resulting in free fatty acids, triglycerides, phospholipids, and cholesterol.
Athira Demitri
doaj  

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