Results 241 to 250 of about 28,679 (286)

ALCAT1 promotes diabetic cardiomyopathy by linking myocardial tetralinoleoyl cardiolipin deficiency to lipotoxicity. [PDF]

Mol Ther
Jia D, Shi Y.
europepmc   +1 more source

The lipid-podocyte axis: emerging clues in membranous nephropathy pathogenesis. [PDF]

Front Med (Lausanne)
Ma S, Chang M, Zhang D, Wang Y, Zhang S, Wang H, Liu Y.   +6 more
europepmc   +1 more source

Dysfunctional Lipid-Induced Secretion of Glucagon-Like Peptide-2(GLP-2), but Not of Incretins Glucagon-Like Peptide-1(GLP-1)/Glucose-Dependent Insulinotropic Polypeptide(GIP), Promotes Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Onset and Progression Through Gut Barrier Disruption and Endotoxemia. [PDF]

MedComm (2020)
Musso G, Pinach S, Mella A, De Michieli F, Calabrese A, Trifiro D, Petrangolini G, Cassader M, Mariano F, Gambino R.   +9 more
europepmc   +1 more source

Palmitate impairs autophagic degradation via oxidative stress/perilysosomal Ca2+ overload/mTORC1 activation pathway in pancreatic β cells. [PDF]

JCI Insight
Nguyen HT, Ly LD, Ngo TTT, Lee SK, Noriega Polo C, Lee S, Lee T, Cha SK, Yasasilka XR, Cho KW, Lee MS, Wiederkehr A, Wollheim CB, Park KS.   +13 more
europepmc   +1 more source

Ginsenosides for the Management of Metabolic Dysfunction-Associated Fatty Liver Disease: A Research Update. [PDF]

Nutrients
Zhang K, Qin Z, Guo Q, Lu J, Luo H, Zha L.   +5 more
europepmc   +1 more source

Fatty Acids and Their Roles in Cardiac Physiology and Pathology: Mechanistic and Interventional Studies. [PDF]

Nutrients
Mallick R, Bhowmik P, Chowdhury P, Duttaroy AK.   +3 more
europepmc   +1 more source

FATP2 at the crossroads of fatty acid transport, lipotoxicity, and complex disease. [PDF]

J Clin Invest
Black PN, DiRusso CC.
europepmc   +1 more source

Imbalance of mitochondria and abnormalities in lipid metabolism in Diabetic Tubulopathy. [PDF]

Ann Med
Sun C, Li Y, Tao Y, Wu Q, Liu B, Zhou Y.
europepmc   +1 more source

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Lipotoxicity in the heart

Current Hypertension Reports, 2005
Cardiomyopathy is associated with both rare genetic metabolic abnormalities and highly prevalent diseases characterized by elevated serum triglycerides and nonesterified fatty acids, such as obesity and type 2 diabetes. In these disorders, an imbalance between fatty acid uptake and utilization leads to the inappropriate accumulation of free fatty acids
Nica M, Borradaile, Jean E, Schaffer
openaire   +2 more sources