Results 111 to 120 of about 112,955 (338)

Tomato prosystemin gene in other Solanaceae [PDF]

, 2009
Systemin, an octadeca-peptide isolated from tomato, is a signalling molecule involved in local and systemic wound response. It regulates the activation of more than twenty defensive genes in tomato plants in response to herbivore attacks.
Araujo Burgos, Tania
core   +1 more source

Polyphenolic Activation of Basophils Explains Alcohol Hypersensitivity in AERD

The Laryngoscope, EarlyView.
The mechanism behind alcohol sensitivity in AERD has not been previously characterized. This study demonstrates the activation of basophils in patients with CRSwNP and AERD by polyphenolic compounds, but not ethanol. Since these compounds can be found in alcoholic beverages in similar frequencies by which they trigger symptoms, this research provides a
Spencer C. Payne, William Eschenbacher, Ryan Stepp, Larry Borish   +3 more
wiley   +1 more source

Sterol Derivatives Specifically Increase Anti-Inflammatory Oxylipin Formation in M2-like Macrophages by LXR-Mediated Induction of 15-LOX

Molecules
The understanding of the role of LXR in the regulation of macrophages during inflammation is emerging. Here, we show that LXR agonist T09 specifically increases 15-LOX abundance in primary human M2 macrophages.
Reiichi Ohno, Malwina Mainka, Rebecca Kirchhoff, Nicole M. Hartung, Nils Helge Schebb   +4 more
doaj   +1 more source

Changes in the microsomal proteome of tomato fruit during ripening [PDF]

, 2019
The variations in the membrane proteome of tomato fruit pericarp during ripening have been investigated by mass spectrometry-based label-free proteomics.
De Lorenzo, Giulia, Fabbri, Claudia, Licursi, Valerio, Mattei, Benedetta, Negri, Rodolfo, Pontiggia, Daniela, Spinelli, Francesco   +6 more
core   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

BML-111, the agonist of lipoxin A4, suppresses epithelial-mesenchymal transition and migration of MCF-7 cells via regulating the lipoxygenase pathway

, 2023
Fen Xu, Xiaoyan Zhou, Lan Lin, Jing Xu, Yu Feng, Yuanqiao He, Hua Hao   +6 more
openalex   +1 more source

Development and adoption of Kernza—A perennial grain crop for sustainable agriculture

PLANTS, PEOPLE, PLANET, EarlyView.
Annual cereal grains account for ~50% of human food calories, but cultivation of these crops has resulted in major environmental and social issues worldwide. For nearly three decades, researchers have been breeding intermediate wheatgrass—a perennial cool‐season grass—to serve as the world's first commercial‐scale perennial grain crop to improve ...
Jessica L. Gutknecht, James A. Anderson, George Annor, Prabin Bajgain, Timothy E. Crews, Colin Cureton, Lee DeHaan, Erin Meier, Tessa Peters, Valentín Picasso, Evelyn C. Reilly, Aaron Reser, Tara Ritter, Aubrey Streit Krug, Nicole Tautges, Jacob M. Jungers   +15 more
wiley   +1 more source

15‐Lipoxygenase‐1 expression suppresses the invasive properties of colorectal carcinoma cell lines HCT‐116 and HT‐29 [PDF]

, 2009
İsmail Çimen, Seda Tuncay Cagatay, Sreeparna Banerjee   +2 more
openalex   +1 more source

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

Clinical &Experimental Allergy, EarlyView.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna, Christina Morgenstern, Katharina Poglitsch, Tamara Arnoldner, Katharina Gangl, Tina J. Bartosik, Nicholas J. Campion, Aldine Tu, Victoria Stanek, Sven Schneider, Christine Bangert   +10 more
wiley   +1 more source

Purification and Partial Characterization of a Membrane-Associated Lipoxygenase in Tomato Fruit [PDF]

, 1992
Caroline Bowsher, Bonita J. M. Ferrie, Sibdas Ghosh, James F. Todd, John E. Thompson, Steven J. Rothstein   +5 more
openalex   +1 more source