Size of chloroplasts in Arabidopsis mesophyll cells affects jasmonate biosynthesis
The relationship between chloroplast structure and hormone biosynthesis capacity is poorly understood. This study shows that mutants harbouring giant chloroplasts produce more jasmonic acid upon mechanical stress than wild‐type plants, suggesting that organellar architecture is a previously unrecognized factor associated with plant hormone biosynthesis
R. Baral +6 more
wiley +1 more source
Structural and computational supported development of 2,5-disubstituted-1,3,4-oxadiazole analogues as active LOX, urease, and α-glucosidase inhibitors. [PDF]
Javid J +11 more
europepmc +1 more source
SUMMARY Plant‐parasitic nematodes deploy secreted effector proteins that reprogram host cellular processes to establish parasitism. Here, we characterized Mi1D08B, a putative dorsal‐gland effector from the root‐knot nematode Meloidogyne incognita and defined its role in subverting soybean jasmonate‐mediated immunity. Mi1D08B is conserved across several
Peitong Li +10 more
wiley +1 more source
Cross-Reactivity and Cross-Intolerance Among Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Clinical Patterns, COX-1-Mediated Mechanisms, and Implications for COX-2 Inhibitors and Paracetamol. [PDF]
Andryszkiewicz W +4 more
europepmc +1 more source
Reengineering an azaphilone biosynthesis pathway in Aspergillus nidulans to create lipoxygenase inhibitors. [PDF]
Somoza AD +4 more
europepmc +1 more source
Synthesis, characterization, and lipoxygenase inhibition of salicylaldehyde-derived schiff base metal complexes: enzymatic and in silico evaluation using quinoa lipoxygenase. [PDF]
Ereminsoy E +4 more
europepmc +1 more source
The role of ALOX15 in inflammation-related diseases. [PDF]
Tang R +5 more
europepmc +1 more source
Overexpression and knockdown of 5-lipoxygenase regulates the migration and invasion of colorectal cancer cells. [PDF]
Li X +7 more
europepmc +1 more source
Identification of a Potential Dual-Target Candidate Against RSV F Protein and 15-LOX from TCMSP: Integrating Virtual Screening, Molecular Dynamics, and Experimental Evaluation. [PDF]
Zhou X +7 more
europepmc +1 more source
Recent Advances in Dual COX/LOX Inhibitor Design (2020-2024): Establishing "The Rule of Four for Inflammation". [PDF]
Chatzipieris FP +4 more
europepmc +1 more source

