Results 171 to 180 of about 25,002 (268)

From Metabolites to Mechanisms: Scorzonera parviflora Aerial Parts and Roots Extracts Profiled by UPLC‐ESI‐MS/MS, In Vitro/In Silico Tests, and Network Analysis

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Scorzonera parviflora is considered a promising candidate for applications in the pharmaceutical, nutraceutical, and natural product industries. ABSTRACT In the present study, the extraction of Scorzonera parviflora aerial parts and roots was performed using four solvents, namely ethyl acetate (EA), ethanol, ethanol/water, and water. The total phenolic
Gokhan Zengin, Nilofar Nilofar, Gunes Ak, Eliana Fernandes, Luísa Custódio, Maria João Rodrigues, Shaza Aly, Omayma A. Eldahshan, Abdel Nasser Singab, Evren Yildiztugay, Milena Terzic, Meng‐Yao Li   +11 more
wiley   +1 more source

Using generalized quantitative structure–property relationship (QSPR) models to predict host cell protein retention in ion‐exchange chromatography

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 7, Page 1420-1428, July 2026.
Abstract BACKGROUND Selecting an optimal chromatography resin during biopharmaceutical downstream process development is a great challenge. This is especially the case for recombinant subunit vaccines, where product properties vary greatly and recovery often involves cell lysis, which yields a complex mixture of different host cell materials. Host cell
Tim Neijenhuis, Olivier Le Bussy, Geoffroy Geldhof, Marieke E Klijn, Marcel Ottens   +4 more
wiley   +1 more source

The potential of 12/15-lipoxygenase inhibitors in stroke therapy. [PDF]

Future Med Chem, 2014
van Leyen K, Holman TR, Maloney DJ.
europepmc   +1 more source

Sorafenib Restores Pentose Phosphate Pathway‐Related Redox Homeostasis via the c‐Raf/HSP90/G6PD Axis in Hepatic Ischemia‐Reperfusion Injury

MedComm, Volume 7, Issue 7, July 2026.
Proposed mechanism of middle‐dose sorafenib modulates redox homeostasis via c‐Raf/HSP90/G6PD axis to attenuate hepatic IRI. This study demonstrates that middle‐dose sorafenib mitigates hepatic IRI through the c‐Raf/HSP90/G6PD axis to enhance pentose phosphate pathway‐mediated antioxidant defense and redox homeostasis, thereby alleviating inflammatory ...
Fengqiang Gao, Libin Dong, Yawen Tan, Zhen Zhang, Shengjun Xu, Zijian Lou, Yichao Wu, Siyu Chen, Li Zhuang, Zhengxing Lian, Shusen Zheng, Nasha Qiu, Kai Wang, Xiao Xu   +13 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Fatty Liver Disease: From Pathogenesis to Treatment

MedComm, Volume 7, Issue 7, July 2026.
Extracellular vesicles play a crucial role in interorgan crosstalk of adipose–liver and gut–liver axes and hold potential as therapeutic targets and drug delivery systems for metabolic dysfunction‐associated fatty liver disease (MAFLD). Abbreviations: AT: adipose tissue; EVs: extracellular vesicles; HL: healthy liver; NAFL: nonalcoholic fatty liver ...
Zhifu Cui, Xiaxia Du, Felix Kwame Amevor, Yaoyao Xia, You Yang, Lingbin Liu   +5 more
wiley   +1 more source

Description of the rate‐limiting hydrogen tunneling mechanism for plant 9‐ and 13‐lipoxygenases

Protein Science, Volume 35, Issue 7, July 2026.
Abstract Soybean lipoxygenase (GmLOX1), a plant 13‐LOX, has long been considered a model protein for non‐trivial, quantum hydrogen tunneling in enzyme catalysis. Hydrogen tunneling mechanisms have also been confirmed for LOXs across mammalian, fungal, and bacterial kingdoms.
Alex Kockler, Katherine Ray, Jordan King, Eric Anderson, Joi Walker, Nathaniel Gilbert, Patrick Horn, Adam R. Offenbacher   +7 more
wiley   +1 more source

Barrett’s dysplasia – adenocarcinoma: role of the leukotriene pathway and treatment with radiofrequency ablation [PDF]

, 2012
Boger, Christopher Philip Coryndon
core  

Texture Engineering of Nondairy Yogurt Alternatives: Ingredient Selection, Processing Strategies, and the Role of In Situ Dextrans

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.
ABSTRACT A global shift from diets rich in animal‐based products toward plant‐based diets has been widely promoted as a key strategy for creating more sustainable food systems. However, the adoption of plant‐based alternatives depends on multiple factors, including consumer preferences, sensory quality, product affordability, and availability, in ...
Yan Xu, Ndegwa Henry Maina, Yaqin Wang
wiley   +1 more source

Deciphering Antidiabetic, Anti-Inflammatory, and Anti-Cholinergic Bioactivities of Withania somnifera (L) Dunal Root Extract: An In Vitro and In Silico Investigation. [PDF]

Chem Biodivers
Mulelu L, Manjia JN, Olofinsan KA, Xulu L, Matsabisa MG.   +4 more
europepmc   +1 more source

Coumarin-Amino Acid Hybrids Used as Possible Multifactorial Anti-Inflammatory Agents. [PDF]

Int J Mol Sci
Fotopoulos I, Hadjipavlou-Litina D.
europepmc   +1 more source