Results 171 to 180 of about 44,003 (300)
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
MedComm – Future Medicine, Volume 5, Issue 2, June 2026.Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
A Roadmap for Breeding Sweet Tomatoes
Modern Agriculture, Volume 4, Issue 1, June 2026.This graphical abstract outlines four breeding strategies for enhancing sugar content and sweetness in tomato fruits: (1) Identification of key genes and functional variant loci regulating fruit sugar accumulation through systematic germplasm collection, genome‐wide association studies (GWAS), map‐based cloning, and reverse genetics approaches.
Jie Chen, Hongjun Lyu, Jinzhe Zhang
wiley +1 more source
Lipoxygenase inhibitor peptides and their use
, 2006 The present invention is in the field of enzyme inhibition. In particular it relates to peptide inhibitors for lipoxygenases. The lipoxygenase peptide inhibitors of have the potential to be used as therapeutic drugs as well as food preservatives.
Schurink, M. +3 more
openaire +1 more source
Houston, we have a problem: Coagulation concerns during long‐term spaceflight
Experimental Physiology, EarlyView.
Lewis Fall, Damian M. Bailey
wiley +1 more source
Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics
MedComm – Oncology, Volume 5, Issue 2, June 2026.Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang +7 more
wiley +1 more source
ChemistryOpen, Volume 15, Issue 6, June 2026.Thiosemicarbazones (TSC) have demonstrated promise as new chemotherapeutic agents against melanoma in both in vitro and In vivo studies. TSC are powerful metal coordinating agents, coordinating transition metal ions such as zinc, copper and iron in multiple oxidation states. It is this metal coordination that imparts the anticancer activity.
Rohina Alim +2 more
wiley +1 more source
Protein Science, Volume 35, Issue 6, June 2026.Abstract The leucine‐rich repeat‐containing G protein‐coupled receptor 6 (LGR6) has a potential role in inflammation resolution and different cancer processes. In this study, we employed computational techniques, including molecular docking and molecular dynamics simulations of mammalian membrane‐embeded systems, to understand the activation mechanism ...
Álex Pérez‐Sánchez +3 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT Kaempferol has been shown to be beneficial in the treatment of Alzheimer's disease (AD) in animal models. However, the action mechanism remains unclear. AKR1B1 has been identified as a target of kaempferol, initially suggested by the Therapeutic Target Database, DrugBank, and PubChem, and subsequently confirmed through experimental validation.
Le Li +5 more
wiley +1 more source
Sustainable Food Proteins, Volume 4, Issue 2, June 2026.The review provides a comprehensive comparison in terms comparison of commercially established and emerging plant protein sources, focusing on their structural, rheological, and sensory attributes for developing sustainable plant‐based meat analogues (PBMAs).
Mian N. Riaz +3 more
wiley +1 more source
Anti-inflammatory activity of beta-sitosterol in a model of oxazolone-induced contact delayed type hypersensitivity. [PDF]
, 2006 Giner, RM, Prieto-Garcia, JM, Recio, MC
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