Results 201 to 210 of about 46,425 (297)

Paeonol Inhibits Cell Growth by Inducing Ferroptosis in Human Glioma Cells

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT Paeonol (PAE), a phenolic phytochemical derived from traditional Chinese medicinal plants, exhibits multifaceted pharmacological properties including demonstrated antitumor efficacy against hepatic, gastric, and breast carcinomas. However, its therapeutic potential in glioma remains unexplored.
Xin Li   +8 more
wiley   +1 more source

Is Ferroptosis the Mechanistic Bridge Connecting Iron Dysregulation to Muscle Wasting and Functional Decline in Aging?

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This work proposes ferroptosis as a mechanistic driver of age‐related muscle dysfunction, whereby iron dyshomeostasis and impaired antioxidant capacity promote lipid peroxidation, and eventually trigger ferroptosis, leading to muscle wasting, and ultimately contributing to weakness and functional decline with aging.
Rola S. Zeidan   +6 more
wiley   +1 more source

Integration of light quality signals regulates ABA abundance and stomatal movements during seedling establishment

open access: yesNew Phytologist, Volume 249, Issue 3, Page 1253-1267, February 2026.
Summary Obtaining sufficient light for photosynthesis and avoiding desiccation are two key challenges faced by seedlings during early establishment. Perception of light quality via specialised photoreceptors signals the availability of sunlight for photosynthesis.
Mathilda Gustavsson   +3 more
wiley   +1 more source

Environmental modulators of vascular physiology and inflammation

open access: yesExperimental Physiology, Volume 111, Issue 2, Page 321-334, 1 February 2026.
Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne   +3 more
wiley   +1 more source

Lifestyle implications of the paradox and management of oxidative stress in sperm

open access: yesThe Journal of Physiology, Volume 604, Issue 3, Page 1028-1044, 1 February 2026.
Abstract figure legend Lifestyle factors influencing male fertility. Schematic overview of lifestyle factors with beneficial (left) and detrimental (right) effects on male fertility. A balanced diet, regular moderate physical activity and stress management strategies support sperm function and redox homeostasis.
Giuseppe T. Patané   +6 more
wiley   +1 more source

5-Lipoxygenase inhibitors isolated from Gardeniae Fructus.

open access: yesChemical and Pharmaceutical Bulletin, 1988
M, Nishizawa   +4 more
openaire   +3 more sources

The Microbiome Modulates Corneal Wound Healing via the Induction of Cholesterol Sulfotransferase Pathway

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Antibiotic‐mediated disruption of commensal microbiota increases corneal cholesterol sulfate (CS) production through upregulation of SULT2B1, resulting in impaired corneal epithelial wound healing. Elevated CS suppresses neutrophil recruitment and epithelial cell migration via inhibition of the DOCK2–Rac pathway.
Mamoru Ogawa   +6 more
wiley   +1 more source

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