Liquid–Liquid Phase Separation in Cardiovascular Diseases
Cells, 2022 Liquid–liquid phase separation (LLPS) is a biochemical process in cells that can drive proteins, RNA, and other molecules to concentrate into droplets.
Yuanxi Mo +8 more
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Biomolecular Liquid–Liquid Phase Separation for Biotechnology
BioTech, 2023 The liquid–liquid phase separation (LLPS) of biomolecules induces condensed assemblies called liquid droplets or membrane-less organelles. In contrast to organelles with lipid membrane barriers, the liquid droplets induced by LLPS do not have distinct ...
Sumit Shil +3 more
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Open questions on liquid–liquid phase separation
Communications Chemistry, 2023 Liquid-liquid phase separation (LLPS) underlies the formation of intracellular membraneless compartments in biology and may have played a role in the formation of protocells that concentrate key chemicals during the origins of life.
Evan Spruijt
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Liquid–liquid phase separation within fibrillar networks
Nature Communications, 2023 Complex fibrillar networks mediate liquid–liquid phase separation of biomolecular condensates within the cell. Mechanical interactions between these condensates and the surrounding networks are increasingly implicated in the physiology of the condensates
Jason X. Liu +5 more
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Phase-separation phenomena in solutions of poly(2,6-dimethyl-1,4-phenylene oxide). I. Thermodynamic parameters of solutions in toluene [PDF]
, 1977 New experimental data have been collected on thermodynamic properties of solutions of poly(2,6-dimethyl-1,4-phenylene oxide) (PPO) in toluene. The Flory-Huggins interaction parameters g have been determined from light scattering measurements.
Koenhen, D.M., Smolders, C.A.
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Liquid–liquid phase separation in tumor biology
Signal Transduction and Targeted Therapy, 2022 Liquid–liquid phase separation (LLPS) is a novel principle for explaining the precise spatial and temporal regulation in living cells. LLPS compartmentalizes proteins and nucleic acids into micron-scale, liquid-like, membraneless bodies with specific ...
Xuhui Tong +6 more
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When liquid-liquid phase separation meets viral infections
Frontiers in Immunology, 2022 Eukaryotic cells have both membranous and membraneless organelles. While the formation mechanism of membranous organelles is well understood, the formation mechanism of membraneless organelles remains unknown.
Wenqiang Wei +10 more
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Phase separation in polymer solutions. I. Liquid-liquid phase separation of PPO poly (2, 6-dimethyl 1, 4-phenylene oxide) in binary mixtures with toluene and ternary mixtures with toluene and ethyl alcohol [PDF]
, 1972 In the system poly(2, 6-dimethy1-1, 4-phenylene oxide) (PPO)-toluene three phase separation lines can be detected: the melting point curve, the cloud point curve, and the spinodial.
Emmerik, P.T. van, Smolders, C.A.
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Self-assembly coupled to liquid-liquid phase separation.
PLoS Computational Biology, 2023 Liquid condensate droplets with distinct compositions of proteins and nucleic acids are widespread in biological cells. While it is known that such droplets, or compartments, can regulate irreversible protein aggregation, their effect on reversible self ...
Michael F Hagan, Farzaneh Mohajerani
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Countercurrent chromatography in analytical chemistry (IUPAC technical report) [PDF]
, 2009 © 2009 IUPACCountercurrent chromatography (CCC) is a generic term covering all forms of liquid-liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid
Abbey +112 more
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