Results 31 to 40 of about 6,322,636 (242)

Liquid-Liquid Phase Separation in Nucleation Process of Biomineralization

Frontiers in Chemistry, 2022
Biomineralization is a typical interdisciplinary subject attracting biologists, chemists, and geologists to figure out its potential mechanism. A mounting number of studies have revealed that the classical nucleation theory is not suitable for all ...
Da Qin, Zhen He, Peng Li, Shutian Zhang
doaj   +1 more source

Effects of molecular weight and temperature on liquid–liquid phase separation in particles containing organic species and inorganic salts [PDF]

Atmospheric Chemistry and Physics, 2015
Atmospheric particles containing organic species and inorganic salts may undergo liquid–liquid phase separation when the relative humidity varies between high and low values.
Y. You, A. K. Bertram
doaj   +1 more source

Mitigation of liquid-liquid phase separation of a monoclonal antibody by mutations of negative charges on the Fab surface.

PLoS ONE, 2020
Some monoclonal antibodies undergo liquid-liquid phase separation owing to self-attractive associations involving electrostatic and other soft interactions, thereby rendering monoclonal antibodies unsuitable as therapeutics.
Tatsuji Matsuoka, Ryuki Miyauchi, Nobumi Nagaoka, Jun Hasegawa   +3 more
doaj   +1 more source

Liquid–Liquid Phase Separation and Protective Protein Aggregates in Bacteria

Molecules, 2023
Liquid–liquid phase separation (LLPS) and the formation of membraneless organelles (MLOs) contribute to the spatiotemporal organization of various physiological processes in the cell.
Dorota Kuczyńska-Wiśnik, Karolina Stojowska-Swędrzyńska, Ewa Laskowska   +2 more
doaj   +1 more source

Liquid-liquid extraction with and without a chemical reaction [PDF]

, 2011
The extraction of mercaptans with alkaline solution is accompanied by a second- order instantaneous reaction. As explained in Section 2.2, in this case, the mass transfer coefficients can be calculated as for the physical extraction, since the mass ...
Claudia Irina Koncsag, Alina Barbulescu, Koncsag, Claudia I., Barbulescu, Alina, Claudia Irina   +4 more
core   +1 more source

Liquid-liquid crystalline phase separation of evolving amyloid fibrils

Physical Review Research, 2023
We study the conditions necessary for the onset of liquid-liquid crystalline phase separation (LLCPS) in a system of dynamically evolving amyloid fibrils whose kinetics is controlled by nucleation, growth and fragmentation.
Paride Azzari, Raffaele Mezzenga
doaj   +1 more source

Liquid–liquid phase separation in diseases

MedComm
Liquid–liquid phase separation (LLPS), an emerging biophysical phenomenon, can sequester molecules to implement physiological and pathological functions.
Xinyue Zhang, Lin Yuan, Wanlu Zhang, Yi Zhang, Qun Wu, Chunting Li, Min Wu, Yongye Huang   +7 more
doaj   +1 more source

LEF1 enhances β-catenin transactivation through IDR-dependent liquid–liquid phase separation

Life Science Alliance, 2023
This research elucidates the correlation between liquid–liquid phase separation (LLPS) of LEF1 with β-catenin and their transcriptional activation function, offering a novel therapeutic approach for the treatment of colorectal cancer through LLPS.
Bing Zhao, Zhuoxin Li, Shaoqing Yu, Tingting Li, Wen Wang, Ran Liu, Biyu Zhang, Xiya Fang, Yezhuang Shen, Qiuying Han, Xin Xu, Kai Wang, Weili Gong, Tao Li, Ailing Li, Tao Zhou, Weihua Li, Teng Li   +17 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Regulation of the Liquid–liquid Phase-Separated Droplets of Biomacromolecules by Butterfly-Shaped Gold Nanomaterials [PDF]

, 2022
Liquid–liquid phase-separated (LLPS) droplets play key roles in regulating protein behaviors, such as enzyme compart-mentalization, stress response, and disease pathogenesis, in living cells.
Kentaro, Shiraki, Megumi, Mori, Tatsuya, Murakami, Koji, Takata, Tomohiro, Nobeyama   +4 more
core   +2 more sources