Results 21 to 30 of about 6,017,039 (234)

Liquid - liquid flows in microchannels [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Dore, V, Tsaoulidis, D, Angeli, P, 3rd Micro and Nano Flows Conference (MNF2011)   +3 more
core   +6 more sources

Liquid–liquid phase separation in synaptopathies

Neuroprotection, 2023
Liquid–liquid phase separation has emerged as an important mechanism for regulating cell activity by promoting the formation of membrane‐less condensates.
Huihui Jiang, Haitao Wu
doaj   +1 more source

Open questions on liquid–liquid phase separation

Communications Chemistry, 2023
Liquid-liquid phase separation (LLPS) underlies the formation of intracellular membraneless compartments in biology and may have played a role in the formation of protocells that concentrate key chemicals during the origins of life.
Evan Spruijt
doaj   +1 more source

Liquid–liquid phase separation within fibrillar networks

Nature Communications, 2023
Complex fibrillar networks mediate liquid–liquid phase separation of biomolecular condensates within the cell. Mechanical interactions between these condensates and the surrounding networks are increasingly implicated in the physiology of the condensates
Jason X. Liu, Mikko P. Haataja, Andrej Košmrlj, Sujit S. Datta, Craig B. Arnold, Rodney D. Priestley   +5 more
doaj   +1 more source

Liquid–Liquid Phase Separation in Cardiovascular Diseases

Cells, 2022
Liquid–liquid phase separation (LLPS) is a biochemical process in cells that can drive proteins, RNA, and other molecules to concentrate into droplets.
Yuanxi Mo, Yuliang Feng, Wei Huang, Ning Tan, Xinyi Li, Minwen Jie, Tong Feng, Hao Jiang, Lei Jiang   +8 more
doaj   +1 more source

Biomolecular Liquid–Liquid Phase Separation for Biotechnology

BioTech, 2023
The liquid–liquid phase separation (LLPS) of biomolecules induces condensed assemblies called liquid droplets or membrane-less organelles. In contrast to organelles with lipid membrane barriers, the liquid droplets induced by LLPS do not have distinct ...
Sumit Shil, Mitsuki Tsuruta, Keiko Kawauchi, Daisuke Miyoshi   +3 more
doaj   +1 more source

Liquid–liquid phase separation in tumor biology

Signal Transduction and Targeted Therapy, 2022
Liquid–liquid phase separation (LLPS) is a novel principle for explaining the precise spatial and temporal regulation in living cells. LLPS compartmentalizes proteins and nucleic acids into micron-scale, liquid-like, membraneless bodies with specific ...
Xuhui Tong, Rong Tang, Jin Xu, Wei Wang, Yingjun Zhao, Xianjun Yu, Si Shi   +6 more
doaj   +1 more source

When liquid-liquid phase separation meets viral infections

Frontiers in Immunology, 2022
Eukaryotic cells have both membranous and membraneless organelles. While the formation mechanism of membranous organelles is well understood, the formation mechanism of membraneless organelles remains unknown.
Wenqiang Wei, Lu Bai, Lu Bai, Bing Yan, Weiquan Meng, Hongju Wang, Jingbo Zhai, Jingbo Zhai, Fusheng Si, Chunfu Zheng, Chunfu Zheng   +10 more
doaj   +1 more source

Does Liquid-Liquid Phase Separation Drive Peptide Folding? [PDF]

, 2020
Proline-arginine (PR) dipeptide repeats have been shown to undergo liquid-liquid phase separation and are an example of a growing number of intrinsically disordered proteins that can assemble into membraneless organelles.
Meredith R., Flanagan, Dean N., Edun, Arnaldo, Serrano   +2 more
core   +1 more source

Self-assembly coupled to liquid-liquid phase separation.

PLoS Computational Biology, 2023
Liquid condensate droplets with distinct compositions of proteins and nucleic acids are widespread in biological cells. While it is known that such droplets, or compartments, can regulate irreversible protein aggregation, their effect on reversible self ...
Michael F Hagan, Farzaneh Mohajerani
doaj   +1 more source