Results 251 to 260 of about 342,327 (294)

BAV-LLPS: a database of bacterial, archaea, and virus liquid-liquid phase separation proteins. [PDF]

Bioinformatics
Rodriguez CB, Tunque Cahui RR, Demitroff N, Hirsh L, Devos DP, Boccaccio G, Parisi G.   +6 more
europepmc   +1 more source

Understanding liquid-liquid phase separation through TDP-43: fundamental principles, subcellular compartmentalisation, and role of solid inclusion formation. [PDF]

Genome Biol
Bigi A, Chiti F.
europepmc   +1 more source

Author Correction: The effects of cosolutes and crowding on the kinetics of protein condensate formation based on liquid-liquid phase separation: a pressure-jump relaxation study. [PDF]

Sci Rep
Cinar H, Winter R.
europepmc   +1 more source

Impact of vibrational strong coupling on liquid-liquid phase separation in supramolecular polymers. [PDF]

Chem Sci
Joseph K, Fu H, van der Tol JJB, Steffen W, Ruan F, Fytas G, Meijer EW.   +6 more
europepmc   +1 more source

Correction to: Intrinsic stiffness and <i>Θ</i>-solvent regime in intrinsically disordered proteins: Implications for liquid-liquid phase separation. [PDF]

PNAS Nexus
europepmc   +1 more source

In vitro liquid-liquid phase separation induced by respiratory syncytial virus proteins and RNA

Basse V, Agarwal T, Sneideris T, Richard C, Troussier J, Vasseur J, Debart F, Eléouët J, de Csillery E, Knowles T, Galloux M.   +10 more
europepmc   +1 more source

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Liquid-Liquid Phase Separation in Biology

Annual Review of Cell and Developmental Biology, 2014
Cells organize many of their biochemical reactions in non-membrane compartments. Recent evidence has shown that many of these compartments are liquids that form by phase separation from the cytoplasm. Here we discuss the basic physical concepts necessary to understand the consequences of liquid-like states for biological functions.
Christoph A Weber, Anthony Hyman, Frank JÜLICHER   +2 more
exaly   +6 more sources

Liquid-liquid Phase Separation in Viral Function

Journal of Molecular Biology, 2023
An emerging set of results suggests that liquid-liquid phase separation (LLPS) is the basis for the formation of membrane-less compartments in cells. Evidence is now mounting that various types of virus-induced membrane-less compartments and organelles are also assembled via LLPS.
Xiaoyue, Zhang, Run, Zheng, Zhengshuo, Li, Jian, Ma   +3 more
openaire   +2 more sources

Tau liquid–liquid phase separation in neurodegenerative diseases

Trends in Cell Biology, 2022
Aggregation of the microtubule-associated protein tau plays a major role in Alzheimer's disease and several other neurodegenerative disorders. An exciting recent development is the finding that, akin to some other proteins associated with neurodegenerative disease, tau has a high propensity to condensate via the mechanism of liquid-liquid phase ...
Witold Surewicz, Solomiia Boyko
exaly   +3 more sources

Liquid–Liquid Phase Separation in Chromatin

Cold Spring Harbor Perspectives in Biology, 2021
In eukaryotic cells, protein and RNA factors involved in genome activities like transcription, RNA processing, DNA replication, and repair accumulate in self-organizing membraneless chromatin subcompartments. These structures contribute to efficiently conduct chromatin-mediated reactions and to establish specific cellular programs.
openaire   +2 more sources